小细胞肺癌(SCLC)很少转移到卵巢,鉴于其与原发性卵巢癌的临床特征和组织学特征重叠,难以诊断。由于SCLC和原发性卵巢癌的治疗方法不同,确定卵巢病变的原始部位很重要。该报告描述了转移性卵巢癌与原发性卵巢癌的鉴别诊断。一名46岁的中国女性,有SCLC病史,2018年8月经支气管镜肺活检证实,2018年12月出现腹胀。超声检查和整个腹部计算机断层扫描显示每个卵巢有一个肿块。给予卵巢肿瘤的临时诊断。进行了姑息性全腹部子宫切除术和双侧附件卵巢切除术;以及三个术后化疗疗程。该患者于2019年5月死于多器官衰竭。基于特征性组织学和免疫组织化学染色确定来自SCLC的转移性卵巢癌。
Small cell lung cancer (SCLC) rarely metastasizes to the ovary, and is difficult to diagnose given its overlapping clinical features and histological characteristics with primary ovarian cancer. Since therapies for SCLC and primary ovarian cancer differ, it is important to determine the original site of ovarian lesions. This report describes the differential diagnosis of metastatic from primary ovarian cancer. A 46-year-old Chinese woman with a history of SCLC, confirmed by transbronchial lung biopsy in August 2018, presented with abdominal distension in December 2018. Ultrasound examination and whole abdomen computed tomography showed one mass in each ovary. A provisional diagnosis of ovarian tumor was given. A palliative total abdominal hysterectomy and bilateral salpingo-oophorectomy was performed; and three postoperative courses of chemotherapies. The patient died from multiple organ failure in May 2019. Metastatic ovarian cancer from SCLC was determined based on characteristic histological and immunohistochemical staining.