public health research

  • 文章类型: Journal Article
    目的:探讨2018年至2023年7月期间在相关医学研究未来基金(MRFF)倡议下资助的研究的数量和类型,这些研究涉及公共卫生和预防。
    方法:由六个MRFF倡议资助的项目,与公共卫生和公共卫生相关的目标被>25%的申请人提名为“研究领域”,根据一组公共卫生研究标准进行评估,并根据预防水平进行分类。
    结果:249个资助项目中有57%被归类为公共卫生研究。具有疗效的项目,侧重于三级(32%)和四级(4%)预防,与具有早期预防特征的项目一样常见,重点是原始(7%)和初级(28%)预防。在六项评估计划中,预防和公共卫生研究计划的公共卫生研究比例最低(48%),在预防性研究(30%)中,治疗性(39%)和非预防性(26%)研究占主导地位。
    结论:这项研究强调了与公共卫生相关的MRFF计划中不同水平的公共卫生研究,以及初级和原始预防的比例普遍较低。在与公共卫生相关的倡议中更加重视原始和一级预防研究可以促进澳大利亚的预防。
    结论:在与公共卫生相关的MRFF倡议和项目中,上游预防研究的优先次序似乎还有改进的余地。解决这一问题可能会增强MRFF对澳大利亚公共卫生的好处。
    OBJECTIVE: To explore the amount and type of research funded under relevant Medical Research Future Fund (MRFF) Initiatives that addressed public health and prevention from 2018 to July 2023.
    METHODS: Projects funded by six MRFF Initiatives, with objectives relevant to public health and public health nominated as \"field of research\" by >25% of applicants, were evaluated against a set of public health research criteria and were categorised based on levels of prevention.
    RESULTS: Fifty-seven per cent of 249 funded projects were categorised as public health research. Projects with curative features, focusing on tertiary (32%) and quaternary (4%) prevention, were as common as projects with earlier preventive features, focussed on primordial (7%) and primary (28%) prevention. The Preventive and Public Health Research Initiative had the lowest proportion of public health research (48%) of the six evaluated Initiatives and a dominance of curative (39%) and non-preventive (26%) research over preventive research (30%).
    CONCLUSIONS: This study highlighted variable levels of public health research across public-health-relevant MRFF Initiatives and generally low proportions of primary and primordial prevention. A greater emphasis on primordial and primary prevention research in public-health-relevant Initiatives could advance prevention in Australia.
    CONCLUSIONS: There appears to be scope for improvement in the prioritisation of upstream prevention research in public-health-relevant MRFF Initiatives and projects. Addressing this may enhance the benefit of MRFF to Australian public health.
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  • 文章类型: Journal Article
    临床和公共卫生研究业务的质量管理系统是必不可少的,因为它确保了研究结果的完整性和可靠性。通过在研究实施和操作中实施稳健的质量管理实践,研究团队可以坚持最高标准的研究行为,从而提高研究成果的可信度和可信度。本文阐述了质量管理体系在临床和公共卫生研究操作中的重要性和作用,以及其在最大限度地减少和消除协议偏差方面的功效,并强调了建立研究操作质量管理体系的关键步骤。
    A quality management system for clinical and public health research operations is indispensable because it ensures the integrity and reliability of research outcomes. By implementing a robust quality management practice in research implementation and operation, research teams can uphold the highest standard of research conduct, thereby enhancing the credibility and trustworthiness of research findings. This paper elucidates the significance and role of a quality management system in clinical and public health research operations and its efficacy in minimising and eliminating protocol deviations and highlights the key steps in setting up a quality management system for research operations.
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  • 文章类型: Journal Article
    目标:研究人员和政策制定者对地方和人口健康之间的关联感兴趣。本文的目的是探讨,总结和比较当代澳大利亚地理参考人口健康调查数据集的内容。
    方法:对澳大利亚境内最近(2015年或以后)包含参与者地理信息的人口健康调查进行了搜索。调查响应框架进行了分析,并根据人口统计,危险因素和疾病相关特征。使用交互式Sankey图进行的分析显示了澳大利亚人口健康调查之间内容重叠和差异的程度。
    结果:确定了13个澳大利亚地理参考人群健康调查数据集。跨调查捕获的信息不一致,受访者信息的空间粒度也不一致。最常见的健康和人口统计特征是症状,来自国际疾病和相关健康问题统计分类第11版的体征和临床发现,住房,收入,自我评估的健康和危险因素,包括饮酒,饮食,医疗,身体活动和体重相关问题。Sankey图被在线部署,供公共卫生研究人员使用。
    结论:由于在澳大利亚不同地区进行的调查中收集的信息不一致,因此确定澳大利亚的地点与健康之间的关系变得更加困难。
    结论:公共卫生研究调查场所和健康涉及各州内部和各州之间大量且不一致的信息拼凑而成。这可能会影响广泛的研究问题。此处开发的工具可帮助公共卫生研究人员确定适合其与地点和健康相关的研究查询的调查。
    OBJECTIVE: Associations between place and population health are of interest to researchers and policymakers. The objective of this paper is to explore, summarise and compare content across contemporary Australian geo-referenced population health survey data sets.
    METHODS: A search for recent (2015 or later) population health surveys from within Australia containing geographic information from participants was conducted. Survey response frames were analysed and categorised based on demographic, risk factor and disease-related characteristics. Analysis using interactive Sankey diagrams shows the extent of content overlap and differences between population health surveys in Australia.
    RESULTS: Thirteen Australian geo-referenced population health survey data sets were identified. Information captured across surveys was inconsistent as was the spatial granularity of respondent information. Health and demographic features most frequently captured were symptoms, signs and clinical findings from the International Statistical Classification of Diseases and Related Health Problems version 11, employment, housing, income, self-rated health and risk factors, including alcohol consumption, diet, medical treatments, physical activity and weight-related questions. Sankey diagrams were deployed online for use by public health researchers.
    CONCLUSIONS: Identifying the relationship between place and health in Australia is made more difficult by inconsistencies in information collected across surveys deployed in different regions in Australia.
    CONCLUSIONS: Public health research investigating place and health involves a vast and inconsistent patchwork of information within and across states, which may impact broad-scale research questions. The tools developed here assist public health researchers to identify surveys suitable for their research queries related to place and health.
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  • 文章类型: Journal Article
    背景:近年来,自由经济在全球范围内快速增长,菲律宾也不例外。自由职业者在医疗保健和研究领域变得越来越普遍。早期职业研究人员进行大部分科学研究,并可以通过为该领域带来新的视角和多样性,在促进公共卫生方面发挥关键作用。现有文献主要集中在机构学术环境中早期职业研究人员的经验。这项研究旨在了解菲律宾卫生政策和系统领域的自由早期职业研究人员的经验。
    方法:这项定性研究通过虚拟访谈和焦点小组讨论收集了2022年3月18日至22日的数据。主题和代码是根据开发的主题指南创建的。新的主题和代码在出现时产生。两名研究人员使用先验代码和紧急代码对数据进行编码。通过讨论解决任何编码冲突,直到达成互码协议。2名研究人员考虑了其背景和主题之间的关系,从数据中得出了解释和结论。
    结果:15名现任和前任自由职业者参与了这项研究。大多数是女性,35岁以下,并以本科学位作为最高的教育成就。研究结果突出了早期职业研究人员在以下方面面临的见解和挑战:(1)工作安排,(2)任务,(3)高级研究人员的期望,(4)卫生政策和制度领域的发展,(5)与同行的关系,(6)继续作为自由卫生政策和系统研究员工作的动机。
    结论:这项研究揭示了自由职业早期研究人员面临的挑战,强调在快速变化的劳动力需求和复杂的健康困境中需要加强支持和认可。建议包括结构化指导,专业发展,创新的资助模式,以及建立支持性网络。倡导确保自由职业者融入经济和决策的政策至关重要。未来的研究应该进一步调查他们的经验,包括他们的角色,过渡,以及融资趋势的影响,促进其发展并融入公共卫生研究和政策。
    BACKGROUND: The freelance economy has seen rapid growth worldwide in recent years and the Philippines is not an exception. Freelance workers are becoming increasingly common in healthcare and research. Early career researchers carry out most of scientific research and can play a critical role in advancing public health by bringing new perspectives and diversity to the field. Existing literature has mostly focused on the experiences of early career researchers in an institutional academic setting. This study aimed to understand the experiences of freelance early career researchers in the health policy and systems space in the Philippines.
    METHODS: This qualitative study collected data from 18 to 22 March 2022 through virtual interview and focus group discussions. Themes and codes were created based on the topic guide developed. New themes and codes were generated as they emerged. Two researchers coded the data using both a priori and emergent codes. Any coding conflicts were resolved through discussions until intercoder agreement was reached. Interpretation and conclusions from the data were developed by 2 researchers with consideration for its context and relationship between themes.
    RESULTS: Fifteen current and former freelance researchers participated in the study. Most are female, under 35 years old, and with an undergraduate degree as the highest educational attainment. The findings highlight insights and challenges faced by early career researchers in aspects of: (1) work arrangement, (2) tasks, (3) expectations from senior researchers, (4) development in the health policy and systems field, (5) relationship with peers, and (6) motivations for continuing to work as a freelance health policy and systems researcher.
    CONCLUSIONS: This study reveals the challenges freelance early career researchers face, highlighting the need for enhanced support and recognition amidst rapidly evolving workforce demands and complex health dilemmas. Recommendations include structured mentorship, professional development, innovative funding models, and the establishment of a supportive network. Advocacy for policies ensuring freelancer inclusion in the economy and policy-making is crucial. Future research should investigate their experiences further, including their roles, transitions, and the impacts of funding trends, to foster their development and integration into public health research and policy.
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  • 文章类型: Journal Article
    暂无摘要。
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  • 文章类型: English Abstract
    The routine data of all statutorily insured persons according to the Data Transparency Regulation (DaTraV data) represent a promising data source for the recurrent and timely surveillance of non-communicable diseases (NCDs) in Germany. Thereby, it has become apparent that there is a high demand for reference evaluations that enable quick and regularly repeatable analyses on important NCDs. Against this background, ReFern-01 was initiated, a joint project of the Robert Koch Institute (RKI) and the Federal Institute for Drugs and Medical Devices (BfArM). In collaboration with experts from the field of secondary data analysis and healthcare research, reference evaluations for estimating prevalence, incidence, and mortality for important public health-relevant diseases were developed. First, 11 central NCDs were selected by means of an online survey, and initial case definitions were created in conjunction with a literature review. These were then discussed and agreed upon in a virtual workshop. The created reference evaluations (analysis scripts) allow a standardized estimation of the mentioned epidemiological figures, which are comparable over time and regionally. In addition to providing the results, the scripts will be available at the BfArM for further analysis. Provided that remote access to the analysis of the DaTraV data is available in the future, the results of the ReFern project can strengthen the surveillance of NCDs and support public health actors, for example, in the planning and implementation of health promotion and prevention measures at the federal, state, county, and local levels.
    UNASSIGNED: Die Routinedaten aller gesetzlich Krankenversicherten nach Datentransparenzverordnung (DaTraV-Daten) stellen eine vielversprechende Datenquelle für die wiederkehrende und zeitnahe Surveillance nicht-übertragbarer Erkrankungen (NCD) in Deutschland dar. Dabei hat sich gezeigt, dass ein hoher Bedarf für Referenzauswertungen besteht, die schnelle und regelmäßig wiederholbare Analysen zu wichtigen NCD ermöglichen. Vor diesem Hintergrund wurde „ReFern-01“ initiiert, ein gemeinsames Projekt vom Robert Koch-Institut (RKI) und dem Bundesinstitut für Arzneimittel und Medizinprodukte (BfArM). In Zusammenarbeit mit Expert:innen aus dem Bereich der Sekundärdatenanalyse und Versorgungsforschung wurden Referenzauswertungen zur Schätzung von Prävalenz, Inzidenz und Mortalität für wichtige Public-Health-relevante Erkrankungen erarbeitet. Zunächst wurden mittels einer Onlinebefragung 11 zentrale NCD ausgewählt und in Zusammenschau mit einer Literaturrecherche initiale Falldefinitionen erstellt. Diese wurden anschließend in einem virtuellen Workshop diskutiert und konsentiert. Die erstellten Referenzauswertungen (Analyseskripte) ermöglichen eine standardisierte Schätzung der genannten epidemiologischen Kennzahlen, die über die Zeit und regional vergleichbar sind. Neben der Bereitstellung der Ergebnisse werden die Skripte am BfArM für zukünftige Datennutzende zur Verfügung stehen. Mit dem Fernzugang zur Analyse der DaTraV-Daten, der derzeit am Forschungsdatenzentrum Gesundheit (FDZ Gesundheit) aufgebaut wird, können die Ergebnisse des Projekts ReFern die Surveillance von NCD stärken und Public-Health-Akteur:innen beispielsweise bei der Planung und Umsetzung von Maßnahmen der Gesundheitsförderung und Prävention auf Ebene von Bund, Ländern, Kreisen und Kommunen unterstützen.
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  • 文章类型: Journal Article
    背景:大型基于人群的队列研究的知情同意程序应该是全面且易于使用的。当来自不同社会经济群体和多元文化种族背景的参与者参与其中时,这尤其具有挑战性。最近,越来越多的研究尝试在知情同意程序中使用多媒体。我们描述了数字知情同意应用程序的开发和测试,并详细说明这是否有助于全面和实用的程序,以获得公共卫生研究的知情同意。
    方法:在有年幼子女的父母样本中,我们采用混合方法研究了知情同意书应用的用户体验,并评估了该应用是否可用于充分告知人们并登记他们的同意书.通过半结构化访谈,我们调查了参与者对应用程序的体验和意见,特别关注内容的可理解性和应用程序的可用性。询问了信息保留问题,以评估参与者可以在多大程度上回忆所提供的研究信息的关键方面。
    结果:这项研究的30名参与者在4到15分钟之间使用了该应用程序以表示同意。总的来说,他们发现这款应用设计得很好,信息丰富且易于使用。要了解有关要求知情同意的研究的更多信息,大多数参与者选择观看动画电影,通常被发现以清晰的方式传达信息。鉴定过程遇到了混合反应,有些人觉得这是一种安全的同意方式,而对于其他人来说,这与他们匿名使用数据的观点相矛盾。信息保留问题表明,尽管所有参与者都记得研究的各个方面,不到一半的人满意地回答了所有四个问题。
    结论:我们的研究表明,精心设计的知情同意书应用程序可以成为通知符合条件的参与者并记录同意书的有效工具。尽管如此,一些问题仍然存在,包括对身份识别程序的信任障碍和一些参与者缺乏信息保留。在实施包含数字格式的同意程序时,投资于互补的面对面招聘方法可能是有益的。
    Informed consent procedures for large population-based cohort studies should be comprehensive and easy-to-use. This is particularly challenging when participants from different socio-economic groups and multicultural ethnic backgrounds are involved. Recently, more and more studies have tried to use multimedia in informed consent procedures. We describe the development and testing of a digital informed consent app and elaborate on whether this may contribute to a comprehensive and practical procedure to obtain informed consent for public health research.
    In a sample of parents with young children, we used a mixed method approach to study the user experience of an informed consent app and evaluate whether it can be used to adequately inform people and register their consent. Through semi-structured interviews we investigated participants\' experiences with and opinions about the app, with a special focus on comprehensibility of the content and the usability of the app. Information retention questions were asked to evaluate to what extent participants could recall key aspects of the provided study information.
    The 30 participants in this study used the app between 4 and 15 min to give their consent. Overall, they found the app well-designed, informative and easy to use. To learn more about the study for which informed consent is asked, most of the participants chose to watch the animated film, which was generally found to convey information in a clear manner. The identification process was met with mixed reactions, with some feeling it as a secure way to give consent, while for others it contradicted their view of using data anonymously. Information retention questions showed that while all participants remembered various aspects of the study, fewer than half answered all four questions satisfactorily.
    Our study shows that a well-designed informed consent app can be an effective tool to inform eligible participants and to record consents. Still, some issues remain, including trust barriers towards the identification procedure and lack of information retention in some participants. When implementing consent procedures that incorporate digital formats, it may be beneficial to also invest in a complementary face-to-face recruitment approach.
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  • 文章类型: Journal Article
    背景:复杂系统方法越来越多地用于健康促进和非传染性疾病预防研究,政策与实践。出现了关于采取复杂系统方法的最佳方法的问题,特别是关于人口体力活动(PA)。使用属性模型是理解复杂系统的一种方法。我们旨在研究当前PA研究中使用的复杂系统方法的类型,并确定哪些方法与属性模型所反映的整个系统方法一致。
    方法:进行了范围审查,并搜索了两个数据库。选择了25篇文章,数据分析基于以下内容:所使用的复杂系统研究方法,研究目的,如果使用参与式方法,以及关于系统属性的讨论证据。
    结果:使用了三组方法:系统作图,仿真建模和网络分析。系统映射方法似乎与PA推广的整个系统方法最好,因为它们主要旨在了解复杂的系统,检查变量之间的相互作用和反馈,并使用参与式方法。这些文章中的大多数都侧重于PA(而不是综合研究)。仿真建模方法主要集中在检查复杂问题和确定干预措施上。这些方法通常不侧重于PA或使用参与式方法。虽然网络分析文章侧重于检查复杂的系统和识别干预措施,他们没有专注于PA,也没有使用参与式方法。在文章中以某种方式讨论了所有属性。属性是根据调查结果明确报告的,或者是讨论和结论部分的一部分。系统映射方法似乎与整个系统方法很好地对齐,因为这些方法以某种方式解决了所有属性。我们没有用其他方法找到这个模式。
    结论:使用复杂系统方法的未来研究可能会受益于将属性模型与系统映射方法结合使用。仿真建模和网络分析方法被认为是互补的,当系统映射方法确定了进一步调查的优先级(例如,要实施哪些干预措施或系统中的紧密连接关系)时,可以使用。
    BACKGROUND: Complex systems approaches are increasingly used in health promotion and noncommunicable disease prevention research, policy and practice. Questions emerge as to the best ways to take a complex systems approach, specifically with respect to population physical activity (PA). Using an Attributes Model is one way to understand complex systems. We aimed to examine the types of complex systems methods used in current PA research and identify what methods align with a whole system approach as reflected by an Attributes Model.
    METHODS: A scoping review was conducted and two databases were searched. Twenty-five articles were selected and data analysis was based upon the following: the complex systems research methods used, research aims, if participatory methods were used and evidence of discussion regarding attributes of systems.
    RESULTS: There were three groups of methods used: system mapping, simulation modelling and network analysis. System mapping methods appeared to align best with a whole system approach to PA promotion because they largely aimed to understand complex systems, examined interactions and feedback among variables, and used participatory methods. Most of these articles focused on PA (as opposed to integrated studies). Simulation modelling methods were largely focused on examining complex problems and identifying interventions. These methods did not generally focus on PA or use participatory methods. While network analysis articles focused on examining complex systems and identifying interventions, they did not focus on PA nor use participatory methods. All attributes were discussed in some way in the articles. Attributes were explicitly reported on in terms of findings or were part of discussion and conclusion sections. System mapping methods appear to be well aligned with a whole system approach because these methods addressed all attributes in some way. We did not find this pattern with other methods.
    CONCLUSIONS: Future research using complex systems methods may benefit from applying the Attributes Model in conjunction with system mapping methods. Simulation modelling and network analysis methods are seen as complementary and could be used when system mapping methods identify priorities for further investigation (e.g. what interventions to implement or how densely connected relationships are in systems).
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  • 文章类型: Journal Article
    新冠肺炎疫情进一步加深了全球社会经济和卫生不平等,特别是在经历社会脆弱性的人群中,比如国际移民。持续的封锁和社会距离增加了对难以接触的人群进行公共卫生研究的挑战。这项研究旨在探索在智利大流行期间招募“难以到达”国际移民进行定性公共卫生研究的策略,根据作者的经验。对侧重于智利国际移民的三个定性研究项目的征聘过程进行了回顾性定性评估。所有项目都在COVID-19大流行期间实施,要求补充和灵活的策略:(i)社交媒体;(ii)滚雪球抽样;(iii)社会工作者以及支持移民和移民主导的组织的推荐;(iv)疫苗接种中心和医疗中心;(v)基于社区的招聘。围绕七个新兴的定性类别对这些策略进行了定性评估:(i)封锁期间的可行性;(ii)招聘速度;(iii)地理覆盖范围;(iv)样本多样性;(v)成功面试的比例;(vi)道德考虑;(vii)成本。在大流行期间,让难以接触的国际移民参与公共卫生研究需要不断调整招聘策略。此外,依靠不仅基于互联网的战略,促进了互联网接入有限和数字识字率低的人群的参与。
    The COVID-19 pandemic has further deepened socioeconomic and health inequities worldwide, especially among populations experiencing social vulnerability, such as international migrants. Sustained lockdowns and social distancing have raised challenges to conducting public health research with hard-to-reach populations. This study aims at exploring strategies to recruit \"hard-to-reach\" international migrants for qualitative public health research during the pandemic in Chile, based on the authors\' experience. A retrospective qualitative evaluation process was carried out on the recruitment processes of three qualitative research projects focused on international migrants in Chile. All projects were implemented during the COVID-19 pandemic, demanding complementary and flexible strategies: (i) social media; (ii) snowball sampling; (iii) referrals from social workers and pro-migrant and migrant-led organizations; (iv) vaccination centers and healthcare centers; and (v) community-based recruitment. The strategies are qualitatively evaluated around seven emerging qualitative categories: (i) feasibility during lockdown periods; (ii) speed of recruitment; (iii) geographical coverage; (iv) sample diversity; (v) proportion of successful interviews; (vi) ethical considerations; and (vii) cost. Engaging hard-to-reach international migrants in public health research during the pandemic required constantly adapting recruitment strategies. Furthermore, relying on strategies that were not only Internet-based promoted the participation of populations with limited access to the Internet and low-digital literacy.
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  • 文章类型: Systematic Review
    在公共卫生领域,许多研究正在使用公开的Twitter数据进行,但是这些数据被用来回答的研究问题的类型以及这些项目需要道德监督的程度尚不清楚。
    这篇综述从方法和研究问题的角度描述了使用Twitter数据进行公共卫生研究的现状,地理焦点,和道德方面的考虑,包括获得Twitter处理程序的知情同意。
    我们实施了系统审查,遵循PRISMA(系统审查和荟萃分析的首选报告项目)指南,在2006年1月至2019年10月31日期间发表的文章中,使用Twitter数据进行公共卫生研究的二次分析,它们是使用Socindex上的标准化搜索标准找到的,PsycINFO,和PubMed。在使用Twitter进行主要数据收集时,研究被排除在外。例如用于研究招募或作为传播干预的一部分。
    我们确定了367篇符合资格标准的文章。传染病(n=80,22%)和物质使用(n=66,18%)是这些研究中最常见的主题,和情绪挖掘(n=227,62%),监测(n=224,61%),主题探索(n=217,59%)是最常用的方法。大约三分之一的文章具有全球或全球地理重点;另外三分之一集中在美国。大多数(n=222,60%)的文章使用原生Twitter应用程序编程接口,和大量的剩余(n=102,28%)使用第三方应用程序编程接口。只有三分之一(n=119,32%)的研究寻求机构审查委员会的伦理批准,而其中17%(n=62)包括Twitter用户或推文的识别信息,其中36%(n=131)试图匿名标识符。大多数研究(n=272,79%)包括对编码的度量和可靠性的有效性的讨论(70%用于人类编码的互信度,70%用于计算机算法检查),但是对抽样框架的关注较少,以及样本代表的潜在人口。
    Twitter数据可能对公共卫生研究有用,考虑到它对公开信息的访问。然而,研究在考虑数据源时应该更加谨慎,加入方法,和抽样框架的外部有效性。Further,需要一个伦理框架来帮助指导这一领域的未来研究,特别是当个人,可识别的Twitter用户和推文被共享和讨论。
    PROSPEROCRD42020148170;https://www.crd.约克。AC.uk/prospro/display_record.php?RecordID=148170。
    Much research is being carried out using publicly available Twitter data in the field of public health, but the types of research questions that these data are being used to answer and the extent to which these projects require ethical oversight are not clear.
    This review describes the current state of public health research using Twitter data in terms of methods and research questions, geographic focus, and ethical considerations including obtaining informed consent from Twitter handlers.
    We implemented a systematic review, following PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines, of articles published between January 2006 and October 31, 2019, using Twitter data in secondary analyses for public health research, which were found using standardized search criteria on SocINDEX, PsycINFO, and PubMed. Studies were excluded when using Twitter for primary data collection, such as for study recruitment or as part of a dissemination intervention.
    We identified 367 articles that met eligibility criteria. Infectious disease (n=80, 22%) and substance use (n=66, 18%) were the most common topics for these studies, and sentiment mining (n=227, 62%), surveillance (n=224, 61%), and thematic exploration (n=217, 59%) were the most common methodologies employed. Approximately one-third of articles had a global or worldwide geographic focus; another one-third focused on the United States. The majority (n=222, 60%) of articles used a native Twitter application programming interface, and a significant amount of the remainder (n=102, 28%) used a third-party application programming interface. Only one-third (n=119, 32%) of studies sought ethical approval from an institutional review board, while 17% of them (n=62) included identifying information on Twitter users or tweets and 36% of them (n=131) attempted to anonymize identifiers. Most studies (n=272, 79%) included a discussion on the validity of the measures and reliability of coding (70% for interreliability of human coding and 70% for computer algorithm checks), but less attention was paid to the sampling frame, and what underlying population the sample represented.
    Twitter data may be useful in public health research, given its access to publicly available information. However, studies should exercise greater caution in considering the data sources, accession method, and external validity of the sampling frame. Further, an ethical framework is necessary to help guide future research in this area, especially when individual, identifiable Twitter users and tweets are shared and discussed.
    PROSPERO CRD42020148170; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=148170.
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