软组织钙化经常出现在影像学研究中,代表一个普遍但非特定的发现,从没有明确原因的局部反应到暗示潜在的全身状况。因为像这样的钙化可以由各种原因引起,准确的鉴别诊断至关重要.鉴别诊断需要对患者进行有条理的评估,包括临床表现,病史,放射学和病理学发现,和其他相关因素。通过检查病人的病史和创伤史,我们可以提炼血管钙化的潜在原因,新陈代谢,自身免疫,肿瘤,或创伤起源。此外,常规实验室评估,包括血清钙水平,磷,离子钙,维生素D代谢物,和甲状旁腺激素(PTH),有助于确定代谢病因。我们描述了一名15岁女性患者的罕见骨瘤角膜炎,该患者有假性甲状旁腺功能减退症(PHP)和奥尔布赖特遗传性骨营养不良(AHO)的病史。患者左脚外侧有疼痛性肿块。诊断是基于病史,实验室测试,和成像,导致切除活检和术后完全缓解疼痛。了解此类罕见事件和相关状况对于准确诊断和管理至关重要。
Soft tissue calcifications frequently appear on imaging studies, representing a prevalent but non-specific discovery, varying from a local reaction without clear cause to suggesting an underlying systemic condition. Because calcifications like these can arise from various causes, an accurate differential diagnosis is crucial. Differential diagnosis entails a methodical assessment of the patient, encompassing clinical presentation, medical history, radiological and pathological findings, and other pertinent factors. Through scrutiny of the patient\'s medical and trauma history, we can refine potential causes of calcification to vascular, metabolic, autoimmune, neoplastic, or traumatic origins. Furthermore, routine laboratory assessments, including serum levels of calcium, phosphorus, ionized calcium, vitamin D metabolites, and parathyroid hormone (PTH), aid in identifying metabolic etiologies. We describe a rare occurrence of osteoma cutis in a 15-year-old female patient with a history of
pseudohypoparathyroidism (PHP) and Albright\'s hereditary osteodystrophy (AHO). The patient presented with a painful mass on the lateral side of her left foot. The diagnosis was based on medical history, laboratory tests, and imaging, leading to an excisional biopsy and complete pain relief post-surgery. Understanding such rare occurrences and related conditions is crucial for accurate diagnosis and management.