背景:本研究旨在通过回顾原始研究来确定股骨近端肿瘤切除后髋关节置换的预后结果。
方法:两名研究人员独立搜索PubMed,Embase,科克伦图书馆,和WebofScience数据库从成立到2022年7月17日。然后,文献按照纳入标准进行筛选.基本信息,主要结果,并提取次要结局进行加权合并分析.使用纽卡斯尔-渥太华量表评估纳入文献的质量。
结果:纳入了包括2081例患者的24项回顾性队列研究。保肢率为98%。原发性肿瘤患者的1、2、3、4和5年生存率分别为80、72、65、64和55%,骨转移患者的1、2、3、4和5年生存率分别为44、25、17、14和11%。分别。
结论:随着化疗和放疗的进展,股骨近端肿瘤切除术后的关节重建改善了患者的功能和生活质量。
BACKGROUND: This study aimed to determine the prognostic outcome of hip joint replacement after resection of proximal femoral tumors by reviewing original studies.
METHODS: Two researchers independently searched PubMed, Embase, Cochrane Library, and Web of Science databases from inception to July 17, 2022. Then, the literature was screened by inclusion criteria. The basic information, primary outcomes, and secondary outcomes were extracted for weighted combined analysis. The quality of the included literature was evaluated using the Newcastle-Ottawa scale.
RESULTS: Twenty-four retrospective cohort studies comprising 2081 patients were included. The limb salvage rate was 98%. The survival rates at 1, 2, 3, 4, and 5 years were 80, 72, 65, 64, and 55% for patients with primary tumors and the rate at 1, 2, 3, 4, and 5 years were 44, 25, 17, 14, and 11% for patients with bone metastases, respectively.
CONCLUSIONS: As chemotherapy and radiotherapy treatment progressed, joint reconstruction after proximal femoral tumor resection improved patients\' function and quality of life.