■有新的证据表明,妊娠损失(诱导或自然)与心血管疾病(CVD)的风险增加有关。这项前瞻性纵向研究调查了在首次活产后的前六个月中,先前妊娠损失对CVD风险的影响。
■对1,002,556名低收入妇女的医疗补助索赔进行了检查,以确定妊娠流产史。CVD,糖尿病,和第一次活产前的高脂血症。研究人群分为五组:A:在第一次活产之前没有妊娠损失或CVD病史的妇女;B:在第一次活产之前有妊娠损失且没有CVD的妇女。C:在第一次妊娠结束后并且在其第一次活产之前具有第一次CVD诊断的妇女。D:首次活产前患有CVD且无妊娠流产史的妇女。E:在第一次活产前同时患有CVD和妊娠损失的妇女。
■在控制了年龄之后,种族,居住国,糖尿病和高脂血症史,在第一次活产后的六个月内,CVD的风险为15%,214%,79%和129%更常见的是B组,C,D和E,分别,
妊娠丢失是首次活产后心血管疾病风险的独立危险因素,对于有和没有心血管疾病病史的女性。当CVD在妊娠流产后和第一次活产前首次诊断时,风险最高。
UNASSIGNED: There is emerging evidence suggesting that pregnancy loss (induced or natural) is associated with an increased risk of cardiovascular diseases (CVD). This prospective longitudinal study investigates the effect of prior pregnancy losses on CVD risk during the first six months following a first live birth.
UNASSIGNED: Medicaid claims of 1,002,556 low-income women were examined to identify history of pregnancy losses, CVD, diabetes, and hyperlipidemia prior to first live birth. The study population was categorized into five groups: A: women with no pregnancy loss or CVD history prior to first live birth; B: women with pregnancy loss and no CVD prior to first live birth. C: women with a first CVD diagnosis after a first pregnancy ending in a loss and before their first live birth. D: women with CVD prior to first live birth and no history of pregnancy loss. E: women with both CVD and pregnancy loss prior to their first live birth.
UNASSIGNED: After controlling for age, race, state of residence, and history of diabetes and hyperlipidemia, the risk of CVD in the six-month period following a first live birth were 15%, 214%, 79% and 129% more common for Groups B, C, D and E, respectively, compared to Group A.
UNASSIGNED: Pregnancy loss is an independent risk factor for CVD risk following a first live birth, both for women with and without a prior history of CVD. The risk is highest when CVD is first diagnosed after a pregnancy loss and prior to a first live birth.