population-based survey

基于人口的调查
  • 文章类型: Journal Article
    背景:全球超过4亿育龄妇女使用处方避孕。监测避孕药具的使用是一个主要的公共卫生问题,通常依赖于基于人群的调查。然而,这些调查平均每6年进行一次,不允许对避孕药具的使用进行密切随访。此外,他们的样本量通常太有限,无法研究特定的人群亚组,如低收入人群。卫生行政数据可能是研究避孕药具使用的创新且成本较低的来源。
    目的:我们旨在探索卫生管理数据在研究处方避孕药具使用方面的潜力,并将这些数据与基于调查数据的观察结果进行比较。
    方法:我们选择了所有15-49岁的女性,由法国健康保险覆盖并居住在法国,在卫生行政数据库中,占常住人口的98%(n=14,788,124),在上一次法国人口代表性调查中,健康晴雨表调查,2016年进行(n=4285)。在卫生行政数据中,记录了避孕药具的使用情况,并提供了有关产品的详细信息,而在调查中,这是由妇女自己宣布的。在这两个来源中,对所有处方避孕药具和避孕药具类型的全球避孕药具使用率进行了估计:口服避孕药,宫内节育器(IUD),和植入物。按年龄分析了患病率。
    结果:卫生行政数据中的低收入妇女多于基于人口的调查(1,576,066/14,770,256,11%vs188/4285,7%,分别;P<.001)。在卫生行政数据中,在基于人群的调查中,有47.6%(7034,710/14,770,256;95%CI47.6%-47.7%)的15-49岁女性使用了处方避孕药,而50.5%(2297/4285;95%CI49.1%-52.0%)。考虑到卫生行政数据与调查数据中避孕药具类型的患病率,口服避孕药分别为26.9%(95%CI26.9%-26.9%)和27.7%(95%CI26.4%-29.0%),宫内节育器的17.7%(95%CI17.7%-17.8%)与19.6%(95%CI18.5%-20.8%),和3%(95%CI3.0%-3.0%)与3.2%(95%CI2.7%-3.7%)的植入物。在这两个来源中,这3种避孕药具的总体流行趋势相同.植入物在各个年龄段都很少使用,口服避孕药在年轻女性中使用率很高,而年轻女性的宫内节育器使用率较低。
    结论:与调查数据相比,卫生行政数据显示口服避孕药的总体趋势相同,宫内节育器,和植入物。卫生行政数据的主要优势之一是关于避孕药具使用的高质量信息和大量的观察,允许研究人口的亚组。因此,卫生行政数据似乎是以人口为基础的方法监测避孕的有希望的新来源。它们可以为研究开辟新的视角,并成为指导生殖健康和性健康公共政策的宝贵新资产。
    BACKGROUND: Prescribed contraception is used worldwide by over 400 million women of reproductive age. Monitoring contraceptive use is a major public health issue that usually relies on population-based surveys. However, these surveys are conducted on average every 6 years and do not allow close follow-up of contraceptive use. Moreover, their sample size is often too limited for the study of specific population subgroups such as people with low income. Health administrative data could be an innovative and less costly source to study contraceptive use.
    OBJECTIVE: We aimed to explore the potential of health administrative data to study prescribed contraceptive use and compare these data with observations based on survey data.
    METHODS: We selected all women aged 15-49 years, covered by French health insurance and living in France, in the health administrative database, which covers 98% of the resident population (n=14,788,124), and in the last French population-based representative survey, the Health Barometer Survey, conducted in 2016 (n=4285). In health administrative data, contraceptive use was recorded with detailed information on the product delivered, whereas in the survey, it was self-declared by the women. In both sources, the prevalence of contraceptive use was estimated globally for all prescribed contraceptives and by type of contraceptive: oral contraceptives, intrauterine devices (IUDs), and implants. Prevalences were analyzed by age.
    RESULTS: There were more low-income women in health administrative data than in the population-based survey (1,576,066/14,770,256, 11% vs 188/4285, 7%, respectively; P<.001). In health administrative data, 47.6% (7034,710/14,770,256; 95% CI 47.6%-47.7%) of women aged 15-49 years used a prescribed contraceptive versus 50.5% (2297/4285; 95% CI 49.1%-52.0%) in the population-based survey. Considering prevalences by the type of contraceptive in health administrative data versus survey data, they were 26.9% (95% CI 26.9%-26.9%) versus 27.7% (95% CI 26.4%-29.0%) for oral contraceptives, 17.7% (95% CI 17.7%-17.8%) versus 19.6% (95% CI 18.5%-20.8%) for IUDs, and 3% (95% CI 3.0%-3.0%) versus 3.2% (95% CI 2.7%-3.7%) for implants. In both sources, the same overall tendency in prevalence was observed for these 3 contraceptives. Implants remained little used at all ages, oral contraceptives were highly used among young women, whereas IUD use was low among young women.
    CONCLUSIONS: Compared with survey data, health administrative data exhibited the same overall tendencies for oral contraceptives, IUDs, and implants. One of the main strengths of health administrative data is the high quality of information on contraceptive use and the large number of observations, allowing studies of subgroups of population. Health administrative data therefore appear as a promising new source to monitor contraception in a population-based approach. They could open new perspectives for research and be a valuable new asset to guide public policies on reproductive and sexual health.
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  • 文章类型: Preprint
    鸡是动物蛋白质的重要来源,营养,许多低收入和中等收入国家(LMICs)的收入。它们也是导致儿童疾病负担的肠病原体的主要储存库。食物系统存在将肠病原体从家禽传播给人类的风险,但是缺乏有关购买模式的人口数据,所有权,以及在LMICs中食用活鸡及其产品,以更好地表征这种风险。
    要评估鸡肉购买情况,所有权,和消费实践,我们在马普托使用结构化问卷进行了一项基于人群的调查,2021年莫桑比克。使用多阶段整群抽样来获得我们研究区域中具有代表性的家庭样本。为了最小化抽样偏差并确保代表性样本,我们使用地区级人口数据和估计的加权人口水平值应用调查加权.
    马普托570户户主完成了我们的调查。这些家庭中约有一半在调查日期的前一周购买了肉鸡肉(占家庭的加权百分比:44.8%)和鸡蛋(46.5%),而本地鸡肉不太受欢迎(1,950,1.1%)。鸡肉产品最常见的来源是街角商店(即,街道上的小型便利店),其次是湿市场。15.6%的家庭饲养活鸡,在进行家访时,大多数家庭的地板或地面都观察到了鸡粪。
    我们的研究结果表明,在这种情况下,家禽是动物蛋白质的主要来源。随着未来几十年中低收入国家家禽养殖的预期增长,确保城市地区鸡肉产品主要来源(街角商店和湿货市场)的食品安全对于减轻健康风险至关重要。
    UNASSIGNED: Chickens are an important source of animal protein, nutrition, and income in many low- and middle-income countries (LMICs). They are also a major reservoir of enteropathogens that contribute to the burden of illnesses among children. Food systems present a risk for transmission of enteropathogens from poultry to humans, but there is a lack of population-level data on the pattern of purchase, ownership, and consumption of live chickens and their products in LMICs to better characterize that risk.
    UNASSIGNED: To assess chicken purchase, ownership, and consumption practices, we conducted a population-based survey using a structured questionnaire in Maputo, Mozambique in 2021. Multi-stage cluster sampling was used to obtain a representative sample of households in our study area. To minimize sampling bias and ensure a representative sample, we applied survey weighting using district-level population data and estimated weighted population-level values.
    UNASSIGNED: Heads of 570 households in Maputo completed our survey. Approximately half of these households purchased broiler chicken meat (weighted percentage of households: 44.8%) and eggs (46.5%) in the previous week of the survey date, while indigenous chicken meat was less popular (1,950, 1.1%). The most common source of chicken products was corner stores (i.e., small convenience shops on streets), followed by wet markets. Live chickens were raised by 15.6% of households, and chicken feces were observed on the floor or ground at the majority of these households during house visits.
    UNASSIGNED: Our findings suggest that poultry provides a major source of animal protein in this setting. With the predicted growth of poultry farming in LMICs in the coming decades, ensuring food safety at the primary sources of chicken products (corner stores and wet markets) in urban areas will be critical to mitigate health risks.
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  • 文章类型: Journal Article
    背景:数字健康技术提供了改善老年人日常生活的潜力,有效地保持健康,并允许老化到位。尽管越来越多的好处和优势的证据,在老年人中采用数字干预措施的准备程度仍未得到充分探索。
    目的:本研究旨在探讨社会人口学与health-,以及日常生活中与生活方式相关的因素和技术使用以及社区居住的老年人准备采用远程医疗,带短信应用程序的智能手机,可穿戴设备,和机器人。
    方法:这是一个横截面,基于人口的调查研究,对居住在南蒂罗尔的75岁或以上的成年人进行分层概率抽样(博尔扎诺/博赞自治省,意大利)。邀请了3600名居住在家中的社区老年人的随机样本,以完成一份问卷,其中包括单个项目(老年人准备使用卫生技术)和量表(PRISMA-7;维护自治服务整合研究计划)。进行描述性和逻辑回归分析以分析数据。
    结果:总计,1695名社区居住的老年人完成了调查(回应率为47%)。就潜在的数字健康技术采用而言,可穿戴设备受到33.7%的青睐(n=571),远程医疗增长30.1%(n=510),智能手机和短信应用增长24.5%(n=416),和辅助机器人的13.7%(n=232)。社会人口统计-,与健康和生活方式相关的因素,以及在日常生活中使用技术,在解释采用数字健康技术的准备方面发挥了重要作用。对于远程医疗,年龄≥85岁(比值比[OR]0.74,95%CI0.56-0.96),财务紧张(OR0.68,95%CI0.49-0.95),每周少于2小时的体力活动(OR0.75,95%CI0.58-0.98)与不准备相关,而讲意大利语的参与者(OR1.54,95%CI1.16-2.05)和经常使用计算机的参与者(OR1.74,95%CI1.16-2.60),智能手机(OR1.69,95%CI1.22-2.35),互联网(OR2.26,95%CI1.47-3.49)报告已准备好采用。
    结论:社区居住的老年人对采用数字健康技术表现出不同的准备,受年龄影响,母语,生活状况,财政资源,身体活动,以及目前使用的技术。研究结果强调,需要有针对性的干预措施和教育计划,以促进社区居住的老年人采用数字健康技术。
    BACKGROUND: Digital health technologies offer the potential to improve the daily lives of older adults, maintain their health efficiently, and allow aging in place. Despite increasing evidence of benefits and advantages, readiness for adopting digital interventions among older people remains underexplored.
    OBJECTIVE: This study aims to explore the relationships between sociodemographic-, health-, and lifestyle-related factors and technology use in everyday life and community-dwelling older adults\' readiness to adopt telemedicine, smartphones with texting apps, wearables, and robotics.
    METHODS: This was a cross-sectional, population-based survey study with a stratified probabilistic sample of adults aged 75 years or older living in South Tyrol (autonomous province of Bolzano/Bozen, Italy). A random sample of 3600 community-dwelling older adults living at home was invited to complete a questionnaire including single items (older adults\' readiness to use health technology) and scales (PRISMA-7; Program of Research on Integration of Services for the Maintenance of Autonomy). Descriptive and logistic regression analyses were performed to analyze the data.
    RESULTS: In total, 1695 community-dwelling older adults completed the survey (for a response rate of 47%). In terms of potential digital health technology adoption, wearable devices were favored by 33.7% (n=571), telemedicine by 30.1% (n=510), smartphones and texting apps by 24.5% (n=416), and assistant robots by 13.7% (n=232). Sociodemographic-, health- and lifestyle-related factors, as well as the use of technology in everyday life, played a significant role in explaining readiness to adopt digital health technologies. For telemedicine, age ≥85 years (odds ratio [OR] 0.74, 95% CI 0.56-0.96), financial constraints (OR 0.68, 95% CI 0.49-0.95), and less than 2 hours of physical activity per week (OR 0.75, 95% CI 0.58-0.98) were associated with nonreadiness, while Italian-speaking participants (OR 1.54, 95% CI 1.16-2.05) and those regularly using computers (OR 1.74, 95% CI 1.16-2.60), smartphones (OR 1.69, 95% CI 1.22-2.35), and the internet (OR 2.26, 95% CI 1.47-3.49) reported readiness for adoption.
    CONCLUSIONS: Community-dwelling older adults display varied readiness toward the adoption of digital health technologies, influenced by age, mother tongue, living situation, financial resources, physical activity, and current use of technology. The findings underscore the need for tailored interventions and educational programs to boost digital health technology adoption among community-dwelling older adults.
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  • 文章类型: Journal Article
    背景:我们以前已经表明头痛在沙特阿拉伯成年人中非常普遍。在这里,我们估计相关的症状负担和参与受损(使用时间受损,失去生产力和脱离社会活动),并使用这些估计来评估沙特阿拉伯与头痛相关的医疗保健需求。
    方法:一项随机横断面调查包括来自全国所有13个地区的2,316名成年人(18-65岁)。它使用了全球头痛运动的标准化方法,并进行了文化上的强制性修改:通过手机使用随机数字拨号而不是上门拜访。调查使用了HARDSHIP问卷,基于ICHD-3beta的诊断问题,关于症状负担的问题,在昨天报告头痛的人中,使用HALT指数查询参与受损的情况,以及关于昨天活动的问题(HY)。医疗保健“需要”是根据受益的可能性来定义的。我们统计了所有≥15天/月的头痛患者,偏头痛≥3天/月,或患有偏头痛或TTH并符合以下两个标准之一:a)发作状态(pTIS)的时间比例>3.3%,强度≥2(中度-重度);b)在3个月内从有偿工作和/或家务中损失的天数≥3天。
    结果:对于所有头痛,平均频率为4.3天/月,平均持续时间8.4h,平均强度2.3(中等)。平均pTIS为3.6%。平均工作损失天数为3.9,家务损失天数为6.6,社交/休闲活动损失天数为2.0。在报告HY的参与者中,37.3%的人可以做不到一半的预期活动,19.8%的人无能为力。在人口层面(即,对于每个成年人),2.5个工作日(可能转化为GDP损失),因头痛而失去了3.6个家庭日和1.3个社交/休闲日。根据HY数据,平均总参与受损(不区分工作,家庭和社交/休闲)为6.8%。共有830人(35.8%)满足了我们的一个或多个需求评估标准。
    结论:非常高的症状负担与参与受损的相应高负担相关。经济成本似乎是巨大的。超过三分之一的成年人被发现需要与头痛相关的医疗保健,因为他们可能会受益,要求高效的护理组织。
    BACKGROUND: We have previously shown headache to be highly prevalent among adults in Saudi Arabia. Here we estimate associated symptom burden and impaired participation (impaired use of time, lost productivity and disengagement from social activity), and use these estimates to assess headache-related health-care needs in Saudi Arabia.
    METHODS: A randomised cross-sectional survey included 2,316 adults (18-65 years) from all 13 regions of the country. It used the standardised methodology of the Global Campaign against Headache with a culturally mandated modification: engagement by cellphone using random digit-dialling rather than door-to-door visits. Enquiry used the HARDSHIP questionnaire, with diagnostic questions based on ICHD-3 beta, questions on symptom burden, enquiries into impaired participation using the HALT index and questions about activity yesterday in those reporting headache yesterday (HY). Health-care \"need\" was defined in terms of likelihood of benefit. We counted all those with headache on ≥ 15 days/month, with migraine on ≥ 3 days/month, or with migraine or TTH and meeting either of two criteria: a) proportion of time in ictal state (pTIS) > 3.3% and intensity ≥ 2 (moderate-severe); b) ≥ 3 lost days from paid work and/or household chores during 3 months.
    RESULTS: For all headache, mean frequency was 4.3 days/month, mean duration 8.4 h, mean intensity 2.3 (moderate). Mean pTIS was 3.6%. Mean lost days from work were 3.9, from household chores 6.6, from social/leisure activities 2.0. Of participants reporting HY, 37.3% could do less than half their expected activity, 19.8% could do nothing. At population-level (i.e., for every adult), 2.5 workdays (potentially translating into lost GDP), 3.6 household days and 1.3 social/leisure days were lost to headache. According to HY data, mean total impaired participation (not distinguishing between work, household and social/leisure) was 6.8%. A total of 830 individuals (35.8%) fulfilled one or more of our needs assessment criteria.
    CONCLUSIONS: A very high symptom burden is associated with a commensurately high burden of impaired participation. The economic cost appears to be enormous. Over a third of the adult population are revealed to require headache-related health care on the basis of being likely to benefit, demanding highly efficient organization of care.
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  • 文章类型: Journal Article
    不仅在患有神经发育障碍(NDS)的儿童中,而且在非NDS中,睡眠问题的患病率都很高。然而,很少有研究调查儿童睡眠问题的人群和特定年龄患病率。此外,调查影响儿童睡眠问题的人口统计学和生活方式相关因素的相关性的研究甚至更少.考虑到这些,本研究的目的是在基于人群的研究中,评估5岁日本儿童的睡眠问题患病率与选定的社会人口统计学和生活方式相关因素之间的相关性.
    研究儿童(SC)从Hirosaki市5岁儿童发育健康检查研究的两个队列中招募。第一组由281名(162名男性,从2014年到2015年招募了119名女性)儿童,第二个队列包括2055名(1068名男性,987名女性)儿童,从2018年到2019年。总共有2,336名SC参与者(1,230名男性和1,106名女性)。为了确定睡眠问题的患病率,使用了日本学龄前儿童睡眠问卷(JSQ-P)。睡眠问题的定义是总分≥86.确定影响睡眠的社会人口统计学和生活方式相关因素,10个因素(NDS诊断,出生月份,托儿所,收入,兄弟姐妹的数量,就寝时间,醒来的时间,睡眠时间,睡眠发作延迟,和屏幕时间)被选择。最后,为了确定睡眠问题的患病率与选定的人口统计学和生活方式相关因素之间的相关性,数据分析采用卡方检验。
    5岁儿童的睡眠问题患病率为18%(369/2,055)。Further,ASD患者的睡眠问题患病率较高(50.4%),ADHD(39.8%),收入<200万日元(30.5%),无兄弟姐妹(24.2%),>22:00的就寝时间(30.7%),>7:30的清醒时间(30.7%),睡眠时间<9小时(25.3%),>30分钟的睡眠开始延迟(35.3%),筛选时间≥2h(21.1%)。
    调查结果显示,5岁儿童的睡眠问题患病率为18%。Further,这些发现建立了睡眠问题和NDS之间的显著相关性,具体的社会人口,和生活方式相关的因素。在考虑已确定的导致参与者睡眠问题的可改变的生活方式相关因素时(即,睡觉/醒来时间和屏幕时间),建议使用睡眠计划来解决这些问题。
    UNASSIGNED: High prevalence of sleep problems in not only children with neurodevelopmental disorders (NDS) but also non NDS has been established. However, there are few studies that have looked into population-based and age-specific prevalence of sleep problems of children. Moreover, there are even fewer studies that have investigated the correlation of demographic and lifestyle-related factors affecting sleep problems in children. Considering these, the purpose of this study is to assess the correlation of the prevalence of sleep problems and selected socio-demographic and lifestyle-related factors in 5-year-old Japanese children in population-based study.
    UNASSIGNED: Study children (SC) were recruited from two cohorts of the Hirosaki City 5-Year-Old Child Developmental Health Checkup Study. The first cohort consisted of 281 (162 males, 119 females) children recruited from 2014 to 2015, and the second cohort consisted of 2055 (1,068 males, 987 females) children from 2018 to 2019. In total there were 2,336 SC participants (1,230 males and 1,106 females). To determine the prevalence of sleep problems the Japanese Sleep Questionnaire for Preschoolers (JSQ-P) was utilized, and sleep problems are defined by a total score of ≥86. To determine socio-demographic and lifestyle-related factors affecting sleep, 10 factors (NDS diagnosis, birth month, childcare place, income, number of siblings, bedtime, waking time, sleeping hours, sleep onset delay, and screen time) were selected. Finally, to determine the correlation between prevalence of sleep problems and the selected demographic and lifestyle-related factors, data was analyzed using chi-square test.
    UNASSIGNED: The prevalence rate of sleep problems in 5-year-olds was 18% (369/2,055). Further, the prevalence of sleep problems was high in participants with ASD (50.4%), ADHD (39.8%), <2 million yen of income (30.5%), no siblings (24.2%), >22:00 of bedtime (30.7%), >7:30 of waking time (30.7%), <9 h of sleeping hours (25.3%), >30 min of sleep onset delay (35.3%), and ≥2 h of screen time (21.1%).
    UNASSIGNED: The findings report 18% prevalence rate of sleep problems in 5-year-old children. Further, the findings establish a significant correlation of sleep problems and NDS, specific socio-demographic, and lifestyle-related factors. In considering the identified modifiable lifestyle-related factors contributing to sleep problems among the participants (i.e., bed/waking times and screen times), sleep programs to address these concerns are suggested.
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  • 文章类型: Journal Article
    背景:高血压是全球最普遍的死亡危险因素。未控制的高血压与过高的发病率和死亡率有关,近一半的高血压患者病情没有得到控制。来自电子健康记录(EHR)系统的数据可能对社区高血压监测有用,填补了当地公共卫生部门的一个空白,“社区卫生评估和支持目前正在进行的公共卫生数据现代化计划。为了识别高血压患者,需要可计算的表型。这些表型利用可用的数据元素-例如生命体征测量和药物-来识别诊断为高血压的患者。然而,有多种方法可以创造一种表型,并且需要确定哪种方法最准确地反映现实世界的流行率,以支持数据现代化计划。
    目的:本研究旨在评估6种基于EHR的高血压患病率估计值与全国调查估计值的可比性。使用不同的可计算表型创建每个患病率估计值。首要目标是确定哪些表型与国家接受的估计最接近。
    方法:使用6种不同的基于EHR的可计算表型,我们计算了马里恩县的高血压患病率估计值,印第安纳州,2014年至2015年。我们从行为危险因素监测系统(BRFSS)中提取了同期的高血压发生率。我们使用双侧t检验(TOST)来检验基于BRFSS和EHR的患病率估计值之间的等效性。TOST是在总体水平上进行的,也是按年龄分层的,性别,和种族。
    结果:使用80%和90%CI,TOST分析得出2种可计算表型,证明与BRFSS估计值大致相等.在表型和人口统计学中注意到性能的差异。具有80%CI的TOST表明,与亚群内的BRFSS估计相比,表型的方差较小,特别是那些与种族类别有关的。总的来说,包括生命体征测量在内的表型差异较小。
    结论:这项研究表明,某些EHR得出的患病率估计值可以作为基于人群的调查估计值的粗略替代品。这些结果证明了批判性评估哪些数据元素包括在基于EHR的计算机表型中的重要性。使用全面的数据源,包含完整的临床数据以及代表人群的数据,对于得出对慢性病的稳健估计至关重要。随着公共卫生部门对数据现代化活动的关注,EHR可以更及时地提供帮助,当地有代表性的慢性病患病率估计。
    BACKGROUND: Hypertension is the most prevalent risk factor for mortality globally. Uncontrolled hypertension is associated with excess morbidity and mortality, and nearly one-half of individuals with hypertension do not have the condition under control. Data from electronic health record (EHR) systems may be useful for community hypertension surveillance, filling a gap in local public health departments\' community health assessments and supporting the public health data modernization initiatives currently underway. To identify patients with hypertension, computable phenotypes are required. These phenotypes leverage available data elements-such as vitals measurements and medications-to identify patients diagnosed with hypertension. However, there are multiple methodologies for creating a phenotype, and the identification of which method most accurately reflects real-world prevalence rates is needed to support data modernization initiatives.
    OBJECTIVE: This study sought to assess the comparability of 6 different EHR-based hypertension prevalence estimates with estimates from a national survey. Each of the prevalence estimates was created using a different computable phenotype. The overarching goal is to identify which phenotypes most closely align with nationally accepted estimations.
    METHODS: Using the 6 different EHR-based computable phenotypes, we calculated hypertension prevalence estimates for Marion County, Indiana, for the period from 2014 to 2015. We extracted hypertension rates from the Behavioral Risk Factor Surveillance System (BRFSS) for the same period. We used the two 1-sided t test (TOST) to test equivalence between BRFSS- and EHR-based prevalence estimates. The TOST was performed at the overall level as well as stratified by age, gender, and race.
    RESULTS: Using both 80% and 90% CIs, the TOST analysis resulted in 2 computable phenotypes demonstrating rough equivalence to BRFSS estimates. Variation in performance was noted across phenotypes as well as demographics. TOST with 80% CIs demonstrated that the phenotypes had less variance compared to BRFSS estimates within subpopulations, particularly those related to racial categories. Overall, less variance occurred on phenotypes that included vitals measurements.
    CONCLUSIONS: This study demonstrates that certain EHR-derived prevalence estimates may serve as rough substitutes for population-based survey estimates. These outcomes demonstrate the importance of critically assessing which data elements to include in EHR-based computer phenotypes. Using comprehensive data sources, containing complete clinical data as well as data representative of the population, are crucial to producing robust estimates of chronic disease. As public health departments look toward data modernization activities, the EHR may serve to assist in more timely, locally representative estimates for chronic disease prevalence.
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  • 文章类型: Journal Article
    性接触模式决定了性传播感染的传播,并且是该领域数学模型的核心输入参数。我们通过比较德国两项独立研究(HaBIDS和SBG)的数据,评估了特定国家/地区的性接触模式参数化对具有相似文化背景的高收入国家/地区的重要性。一个没有系统的性接触模式数据的国家,根据英国全国性态度和生活方式调查(Natsal)的数据,和美国全国家庭增长调查(NSFG),在高收入国家进行的两项最长的性接触研究。我们调查了报告的异性伴侣数量的分布差异,使用加权负二项回归对年龄和性别进行调整(以及按年龄分层)的同性伴侣和双性伴侣。在我们的分析中,英国和美国的参与者报告说,与德国的两项研究相比,终生异性性伴侣的数量要高得多。终生伴侣的差异是由于在英国和美国的年轻年龄组(<24岁)中有许多伴侣的个人比例较高。老年组的合作伙伴获取相似。各国同性伴侣的数量相似,虽然所报告的男女伴侣经历存在异质性,与异性性伴侣观察到的差异一致。这些模式可能导致不同年龄的性传播感染动态大不相同,并且对建模研究的结果有很大的影响。
    Sexual contact patterns determine the spread of sexually transmitted infections and are a central input parameter for mathematical models in this field. We evaluated the importance of country-specific sexual contact pattern parametrization for high-income countries with similar cultural backgrounds by comparing data from two independent studies (HaBIDS and SBG) in Germany, a country without systematic sexual contact pattern data, with data from the National Survey of Sexual Attitudes and Lifestyles (Natsal) in the UK, and the National Survey of Family Growth (NSFG) in the US, the two longest running sexual contact studies in high-income countries. We investigated differences in the distribution of the reported number of opposite-sex partners, same-sex partners and both-sex partners using weighted negative binomial regression adjusted for age and sex (as well as stratified by age). In our analyses, UK and US participants reported a substantially higher number of lifetime opposite-sex sexual partners compared to both German studies. The difference in lifetime partners was caused by a higher proportion of individuals with many partners in the young age group (<24 years) in the UK and the US. Partner acquisition in older age groups was similar. The number of same-sex partners was similar across countries, while there was heterogeneity in the reported experience with partners from both sexes, consistent with the differences observed for opposite-sex sexual partners. These patterns can lead to substantially different dynamics of sexually transmitted infections across ages, and have strong impact on the results of modeling studies.
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  • 文章类型: Journal Article
    背景:已经报道了2型糖尿病风险的差异,包括性别/性别或社会经济地位。从交叉的角度来看,重要的是,不仅要单独考虑社会维度的作用,还有他们的十字路口。这可以更深入地了解不同人群的糖尿病风险和预防需求。
    方法:作为一种交叉知情方法,从横断面调查“疾病知识和信息需求-糖尿病(2017)”中,对德国无已知糖尿病的成年人进行了基于人群的样本,对个体异质性和区分准确性进行了多水平分析(MAIHDA)。糖尿病风险通过德国糖尿病风险评分(GDRS,范围0-122点),根据已确定的自我报告的危险因素估计未来5年内个体患2型糖尿病的风险.将个体嵌套在12个交叉阶层中,由性别/性别组合定义,教育水平,和移民的历史,我们计算了衡量指标,以量化在层次上解释糖尿病风险的个体差异的程度,以及这在多大程度上是由于社会决定因素的累加或乘法交叉效应。
    结果:根据2,253名参与者的数据,我们发现交叉层的判别精度很好(在简单交叉模型中,方差分配系数=14.00%)。模型预测的GDRS均值在29.97之间变化(对应于<2%的“低风险”)在具有高学历和移民史的女性中,和52.73(“仍然低风险”2-5%)在没有移民史的低教育水平的男性。阶层之间GDRS的差异主要由社会决定因素的加性效应(方差与交叉相互作用模型的比例变化=77.95%)来解释,男性和低教育水平与较高的GDRS相关。没有证据表明在各个阶层中具有倍增效应。
    结论:2型糖尿病风险在不同阶层之间存在差异,在某种程度上可以在阶层层面上解释。交叉效应的作用很小,需要进一步研究。研究结果表明,需要针对糖尿病风险增加的大群体采取具体的预防措施,例如男性和受教育程度低的人。
    BACKGROUND: Differences in type 2 diabetes risk have been reported for several sociodemographic determinants including sex/gender or socioeconomic status. From an intersectional perspective, it is important to not only consider the role of social dimensions individually, but also their intersections. This allows for a deeper understanding of diabetes risk and preventive needs among diverse population groups.
    METHODS: As an intersectionality-informed approach, multilevel analysis of individual heterogeneity and discriminatory accuracy (MAIHDA) was used in a population-based sample of adults without known diabetes in Germany from the cross-sectional survey \"Disease knowledge and information needs- Diabetes mellitus (2017)\". Diabetes risk was assessed by the German Diabetes Risk Score (GDRS, range 0-122 points), estimating the individual risk of developing type 2 diabetes within the next 5 years based on established self-reported risk factors. Nesting individuals in 12 intersectional strata defined by combining sex/gender, educational level, and history of migration, we calculated measures to quantify the extent to which individual differences in diabetes risk were explained at strata level, and how much this was due to additive or multiplicative intersectional effects of social determinants.
    RESULTS: Drawing on data of 2,253 participants, we found good discriminatory accuracy of intersectional strata (variance partition coefficient = 14.00% in the simple intersectional model). Model-predicted GDRS means varied between 29.97 (corresponding to a \"low risk\" of < 2%) in women with high educational level and a history of migration, and 52.73 (\"still low risk\" of 2-5%) in men with low educational level without a history of migration. Variance in GDRS between strata was mainly explained by additive effects of social determinants (proportional change in variance to intersectional interaction model = 77.95%) with being male and having low educational level being associated with higher GDRS. There was no evidence of multiplicative effects in individual strata.
    CONCLUSIONS: Type 2 diabetes risk differed between intersectional strata and can to some extent be explained at strata level. The role of intersectional effects was minor and needs to be further investigated. Findings suggest a need for specific preventive measures targeted at large groups with increased diabetes risk, such as men and persons with low educational level.
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  • 文章类型: Journal Article
    背景:在基于人群的调查中估计贫血的标准做法是使用即时护理设备测量一滴毛细血管血液中的血红蛋白(Hb)。新出现的证据表明,取决于血液来源,Hb浓度的差异大于预期。
    目的:与SysmexXN-450血液分析仪检测静脉血的参考方法相比,我们评估了使用不同的血源用HemoCue201+分析仪测量Hb的方法。
    方法:静脉Hb浓度,池化,在乌干达的受控(实验室)和调查(人口健康调查-8试点)环境中,收集了6-59个月的儿童和15-49岁的非孕妇的单滴毛细血管血。使用HemoCue201+分析仪测试从同一个体收集的毛细管和静脉血,并且还使用SysmexXN-450血液学分析仪测量静脉血。使用Lin的一致性相关系数来估计度量之间的一致性,Bland-Altman阴谋,和戴明回归。使用配对t检验和McNemar检验比较均值和患病率,分别。
    结果:使用HemoCue201分析仪测量的Hb与参考方法之间的一致性极限对于静脉最低(1.1至1.96g/dL),其次是汇集的毛细管(1.45至2.27g/dL),和单滴毛细血管血(2.23至3.41g/dL)。比较者之间的平均差异小于0.5g/dL。两种类型的毛细血管血液中的Hb浓度存在统计学上的显着差异。与参考方法相比,合并的毛细血管血液中的贫血患病率较低。
    结论:使用HemoCue201+分析仪通过毛细血管血测得的Hb的变异性高于静脉血,但其影响Hb和贫血估计值有效性的程度需要进一步探索。还需要未来的研究来评估在基于人群的调查中使用静脉血液与毛细血管血液的含义。
    背景:720-OAA-18C-00083;https://clinicaltrials.gov/ct2/show/NCT05059457。
    Standard practice for estimating anemia in population-based surveys is to use a point-of-care device to measure hemoglobin (Hb) in a single drop of capillary blood. Emerging evidence points to larger than expected differences in Hb concentration depending on the blood source.
    We evaluated use of different blood sources to measure Hb with a HemoCue 201+ analyzer compared with the reference method of venous blood tested with a Sysmex XN-450 hematology analyzer.
    Hb concentration in venous, pooled capillary, and single-drop capillary blood were collected in controlled (laboratory) and survey (Demographic Health Survey-8 pilot) settings in Uganda among children 6-59 mo and nonpregnant women 15-49 y. Venous and capillary blood collected from the same individual was tested using a HemoCue 201+ analyzer and the venous blood was also measured with a Sysmex XN-450 hematology analyzer. Agreement between measures was estimated using Lin\'s concordance correlation coefficient, Bland-Altman plots, and Deming regression. Means and prevalences were compared using paired t-tests and McNemar\'s tests, respectively.
    The limits of agreement between Hb measured using a HemoCue 201+ analyzer and the reference method were lowest for venous (1.1-1.96 g/dL), followed by pooled capillary (1.45-2.27 g/dL), and single-drop capillary blood (2.23-3.41 g/dL). Mean differences were <0.5 g/dL across comparators. There were statistically significant differences in Hb concentration from both types of capillary blood. Anemia prevalence was lower in pooled capillary blood compared with the reference method.
    The variability of Hb measured by capillary blood using the HemoCue 201+ analyzer is higher than venous blood but the extent to which this impacts the validity of Hb and anemia estimates requires further exploration. Future research is also needed to evaluate the implications of using venous compared with capillary blood in population-based surveys. This trial was registered at clinicaltrials.gov (NCT05059457).
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  • 文章类型: Journal Article
    单侧前庭功能减退患者症状的存在和强度各不相同。为了更好地了解前庭代偿及其对康复治疗的意义,我们旨在确定哪种扫视和前庭眼反射参数最好地预测单侧前庭功能减退症状的存在。
    从23名有症状和10名目前无症状的单侧前庭功能减退参与者的亚群中分析了视频头部冲动测试数据,嵌入KORA(奥格斯堡地区合作健康研究)FF4研究,KORAS4人群健康调查的第二次随访(2,279名参与者).
    追赶扫视次数较多,隐蔽扫视的比例更高,在单侧前庭功能减退的参与者中,头部冲动发作后200ms处的较大视网膜误差与相关症状相关(分别为p=0.028,p=0.046和p=0.038).经过逐步选择,在最终的逻辑回归模型中保留了200毫秒的追赶扫视次数和视网膜误差,显著优于零模型(p=0.014)。年龄,性别,扫视幅度,扫视延迟,和VOR增加不能预测症状的存在。
    扫视代偿的准确性似乎对于单侧前庭功能减退症状的存在至关重要,强调特定的注视稳定练习在康复中的作用。早期扫视,主要由前庭系统触发,似乎补偿不够准确,导致相关的视网膜误差和需要更多和更准确的追赶扫视,可能是由视觉系统触发的。
    UNASSIGNED: The presence and intensity of symptoms vary in patients with unilateral vestibular hypofunction. We aimed to determine which saccadic and vestibulo-ocular reflex parameters best predict the presence of symptoms in unilateral vestibular hypofunction in order to better understand vestibular compensation and its implications for rehabilitation therapy.
    UNASSIGNED: Video head impulse test data were analyzed from a subpopulation of 23 symptomatic and 10 currently symptom-free participants with unilateral vestibular hypofunction, embedded in the KORA (Cooperative Health Research in the Region of Augsburg) FF4 study, the second follow-up of the KORA S4 population-based health survey (2,279 participants).
    UNASSIGNED: A higher number of catch-up saccades, a higher percentage of covert saccades, and a larger retinal error at 200 ms after the onset of the head impulse were associated with relevant symptoms in participants with unilateral vestibular hypofunction (p = 0.028, p = 0.046, and p = 0.038, respectively). After stepwise selection, the number of catch-up saccades and retinal error at 200 ms remained in the final logistic regression model, which was significantly better than a null model (p = 0.014). Age, gender, saccade amplitude, saccade latency, and VOR gain were not predictive of the presence of symptoms.
    UNASSIGNED: The accuracy of saccadic compensation seems to be crucial for the presence of symptoms in unilateral vestibular hypofunction, highlighting the role of specific gaze stabilization exercises in rehabilitation. Early saccades, mainly triggered by the vestibular system, do not seem to compensate accurately enough, resulting in a relevant retinal error and the need for more as well as more accurate catch-up saccades, probably triggered by the visual system.
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