Wang,Bowen,孟佳彭,,江丽恒,,费芳,,王娟,,李燕,,赵瑞晨,,还有王玉良,.罕见的高海拔红细胞增多症合并自发性脾破裂。高AltMedBiol。00:00-00,2024.-高海拔红细胞增多症,一种以红细胞红细胞质量增加为特征的疾病,长时间暴露在高海拔地区后可能会发生。虽然一些研究已经探索了与高海拔红细胞增多症相关的并发症,目前尚无关于高海拔红细胞增多症引起的自发性脾破裂的文献。这里,我们报道了一例在高海拔地区居住6年的36岁男性急性腹痛和血流动力学不稳定的病例,没有任何创伤史.计算机断层扫描成像显示腹部有大量液体积聚,在随后的剖腹手术中发现脾包膜撕裂。随后的评估证实,长期高海拔暴露继发的红细胞增多症是潜在的病因。该病例提醒人们,高海拔红细胞增多症可能导致严重的并发症,如自发性脾破裂。临床医生应意识到这种潜在的并发症,并在该人群中出现腹痛和血流动力学不稳定的患者的鉴别诊断中考虑它。
Wang, Bowen, Mengjia Peng,, Liheng Jiang,, Fei Fang,, Juan Wang,, Yan Li,, Ruichen Zhao,, and Yuliang Wang,. A Rare Case of High-Altitude
Polycythemia Complicated by Spontaneous Splenic Rupture. High Alt Med Biol. 00:00-00, 2024.-High-altitude
polycythemia, a condition characterized by an increase in red blood cellRBC mass, can occur after prolonged exposure to high altitudes. While several studies have explored the complications associated with high-altitude
polycythemia, there is currently no literature available on spontaneous spleen rupture caused by high-altitude
polycythemia. Here, we reported a case of acute abdominal pain and hemodynamic instability in a 36-year-old male who had been residing at high altitude for 6 years, without any recent history of trauma. Computed tomography imaging revealed significant fluid accumulation in the abdomen, and a tear of the splenic capsule was identified during the following laparotomy. Subsequent evaluations confirmed the presence of
polycythemia secondary to prolonged high-altitude exposure as the underlying etiology. This case served as an important reminder that high-altitude polycythemia could lead to serious complications, such as spontaneous spleen rupture. Clinicians should be aware of this potential complication and consider it in the differential diagnosis of patients presenting with abdominal pain and hemodynamic instability in this population.