■糖尿病足感染是糖尿病的重要并发症,对发病率有很大贡献,死亡率,全球医疗支出。准确的诊断依赖于综合临床评估的综合评估,影像学检查,和微生物分析。管理需要多学科的方法,包括手术干预,抗菌治疗,和先进的伤口护理策略。预防措施在减少发病率和严重程度方面至关重要,强调病人的教育,定期足部检查,早期干预。
■研究人员使用PUBMEDMESH关键词对文献进行了系统回顾。此外,该研究已在审查和传播中心的国际前瞻性系统审查登记册中注册,约克大学(CRD42021277788)。这篇综述提供了在糖尿病足感染中观察到的微生物谱和抗生素敏感性模式的全面概述。
■通过对数据库的搜索,最终确定了2021年至2023年共有2545名患者的13篇文章。总的来说,分离出的主要革兰氏阳性微生物是金黄色葡萄球菌,粪肠球菌,化脓性链球菌,无乳链球菌,和表皮葡萄球菌.而主要的革兰氏阴性包括大肠杆菌,肺炎克雷伯菌,奇异变形杆菌和铜绿假单胞菌。
■糖尿病足感染是一个复杂和多方面的临床实体,需要一种整体的诊断方法,管理,和预防。关于成果和指南建议有效性的高质量研究数据有限,对更新和完善现有DFI管理指南提出了挑战。
■https://www.crd.约克。AC.uk/prospro/display_record.php?ID=CRD42021277788,标识符CRD42021277788。
UNASSIGNED: Diabetic foot infection represents a significant complication of diabetes mellitus, contributing substantially to morbidity, mortality, and healthcare expenditure worldwide. Accurate diagnosis relies on a comprehensive assessment integrating clinical evaluation, imaging studies, and microbiological analysis. Management necessitates a multidisciplinary approach, encompassing surgical intervention, antimicrobial therapy, and advanced wound care strategies. Preventive measures are paramount in reducing the incidence and severity, emphasizing patient education, regular foot screenings, and early intervention.
UNASSIGNED: The researchers performed a systematic review of literature using PUBMED MESH keywords. Additionally, the study was registered in the International Prospective Register of Systematic Reviews at the Center for Reviews and Dissemination, University of York (CRD42021277788). This review provides a comprehensive overview of the microbial spectrum and antibiotic susceptibility patterns observed in diabetic foot infections.
UNASSIGNED: The search through the databases finally identified 13 articles with 2545 patients from 2021 to 2023. Overall, the predominant Gram-positive microbial species isolated were Staphylococcus aureus, Enterococcus fecalis, Streptococcus pyogenes, Streptococcus agalactiae, and Staphylococcus epidermidis. Whereas the predominant Gram-negative included Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis and Pseudomonas aeruginosa.
UNASSIGNED: Diabetic foot infections represent a complex and multifaceted clinical entity, necessitating a holistic approach to diagnosis, management, and prevention. Limited high-quality research data on outcomes and the effectiveness of guideline recommendations pose challenges in updating and refining existing DFI management guidelines.
UNASSIGNED: https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021277788, identifier CRD42021277788.