■这项研究的目的是调查南京成年人的体育锻炼与饮食习惯和心血管危险因素之间的关系。中国。
■2017年进行的横断面调查涉及南京市60.283名年龄≥18岁的个体,中国。采用多阶段分层整群抽样的抽样方法。调整后潜在混杂因素的多变量逻辑回归分析的主要结果是体育锻炼与饮食习惯和心血管风险变量之间的关系。相互作用导致的相对超额风险(RERI),归因于互动的可归属比例(AP),和协同指数(S)用于评估饮食习惯和身体活动之间的累加相互作用。
■调整潜在的混杂因素后,心血管危险因素与缺乏体力活动和不健康饮食的关联显著相关,低密度脂蛋白胆固醇(HLDL-c)(1.64,95%CI[1.47,1.84])和高血压(1.55,95%CI[1.46,1.64])的比值比(ORs)最高.在较高的低密度脂蛋白胆固醇(HLDL-c)的心血管危险因素中发现了缺乏运动和不健康饮食之间的附加相互作用(S,2.57;95%CI[1.27,5.21]),2型糖尿病(T2D)(S,1.96;95%CI[1.23,3.13]),血脂异常(S,1.69;95%CI[1.08,2.66])和高血压(S,1.46;95%CI[1.12,1.89])。他们的RERI为0.39(95%CI[0.18,0.60]),0.22(95%CI[0.09,0.35]),0.11(95%CI[0.03,0.19])和0.17(95%CI[0.06,0.28]),分别。或者是HLDL-c,T2D,高血压和血脂异常的参与者缺乏体力活动和不健康的饮食是24%,15%,11%和8.3%,分别。在肥胖中检测到乘法相互作用,高血压,T2D和HLDL-c。
■不健康的饮食和缺乏运动与心血管危险因素密切相关。这项研究还表明,不健康的饮食和缺乏体力活动相结合,对T2D产生累加效应,高血压,HLDL-c,和血脂异常,表明风险高于这些因素的总和,尤其是HLDL-c。旨在降低高血压等心脏代谢风险的预防策略,T2D,HLDL-c,和血脂异常是针对缺乏体力活动和不健康饮食所必需的。
UNASSIGNED: The aim of this study was to investigate the association between physical activities combined with dietary habits and cardiovascular risk factors in adults from Nanjing, China.
UNASSIGNED: The cross-sectional survey conducted in 2017 involved a sample of 60 283 individuals aged ≥18 years in Nanjing municipality, China. The sampling method used was multistage stratified cluster sampling. The primary outcomes from multivariate logistic regression analysis with adjusted potential confounders were the relationships between physical activities combined with dietary habits and cardiovascular risk variables. Relative excess risk due to interaction (RERI), attributable proportion due to interaction (AP), and synergy index (S) were used to assess an additive interaction between dietary habits and physical activities.
UNASSIGNED: After adjusting potential confounders, cardiovascular risk factors were significantly associated with the association of physical inactivity and unhealthy diet, with the highest odds ratios (ORs) for low density lipoprotein-cholesterol (HLDL-c) (1.64, 95% CI [1.47, 1.84]) and hypertension (1.55, 95% CI [1.46, 1.64]). Additive interactions between physical inactivity and unhealthy diet were found in on cardiovascular risk factors of higher low-density lipoprotein-cholesterol (HLDL-c) (S, 2.57; 95% CI [1.27, 5.21]), type 2 diabetes (T2D) (S, 1.96; 95% CI [1.23, 3.13]), dyslipidemia (S, 1.69; 95% CI [1.08, 2.66]) and hypertension (S, 1.46; 95% CI [1.12, 1.89]). Their RERI was 0.39 (95% CI [0.18, 0.60]), 0.22 (95% CI [0.09, 0.35]), 0.11 (95% CI [0.03, 0.19]) and 0.17 (95% CI [0.06, 0.28]), respectively. OR of being HLDL-c, T2D, hypertension and dyslipidemia in participants of physical inactivity and unhealthy diet was 24%, 15%, 11% and 8.3%, respectively. Multiplicative interaction was detected in obesity, hypertension, T2D and HLDL-c.
UNASSIGNED: An unhealthy diet and physical inactivity were strongly linked to cardiovascular risk factors. This study also showed that an unhealthy diet and physical inactivity combined to produce an additive effect on T2D, hypertension, HLDL-c, and dyslipidemia, suggesting a higher risk than the total of these factors, especially HLDL-c. Preventive strategies aimed at reducing cardiometabolic risks such as hypertension, T2D, HLDL-c, and dyslipidemia are necessary for targeting physical inactivity and unhealthy diet.