DavidMauzerall于1929年7月22日出生在一个小工人阶级家庭,内陆纺织小镇桑福德,缅因州.那些卑微的出身灌输了毕生的节俭和创新精神。1954年在芝加哥大学与FrankWestheimer一起获得物理有机化学博士学位后,那年夏天,他作为博士后加入了洛克菲勒医学研究所(现在的大学),上升到教授的级别,并在他的职业生涯中一直呆在那里。他60多年的工作包括卟啉生物合成,不同结构中的光诱导电子转移反应(溶液,双层脂质膜,反应中心,色谱,和完整的叶子),光合作用的光饱和曲线,光反应的统计处理,和“所有的卟啉。他的研究最终达到了他诗意地称之为“听树叶”的研究,通过使用脉冲光声光谱来探测光合作用的过程和热力学。他的研究小组一直很小;的确,共185篇出版物,39个是单独创作的。简而言之,DavidMauzerall融合了物理有机化学不同学科的深厚知识,光化学,光谱学和生物物理学与巧妙的实验方法,精辟的数学分析,原始的个人诚信,以及对科学的不屈不挠的热爱,以加深我们对光合作用的理解。他创造性地思考——而且总是独立的。他的工作有助于将光合作用和生命起源的领域系统化,并使它们更加定量。本文重点介绍了许多重要的科学发现,并包括了他的家庭成员的评论,朋友,和合作者(GaryBrudvig,GregEdens,PaulFalkowski,AlzattaFogg,G.Govindjee,南希·格林鲍姆,MarilynGunner,哈维·侯,Denise和MicheleMauzerall,托马斯·摩尔,和WilliamParson)作为庆祝他95岁生日的一部分。
David Mauzerall was born on July 22, 1929 to a working-class family in the small, inland textile town of Sanford, Maine. Those humble origins instilled a lifelong frugality and an innovative spirit. After earning his PhD degree in 1954 in physical organic chemistry with Frank Westheimer at the University of Chicago, he joined The Rockefeller Institute for Medical Research (now University) as a postdoctoral fellow that summer, rose to the rank of professor, and remained there for the rest of his career. His work over more than 60 years encompassed porphyrin biosynthesis, photoinduced electron-transfer reactions in diverse architectures (solutions, bilayer lipid membranes, reaction centers, chromatophores, and intact leaves), the light-saturation curve of photosynthesis, statistical treatments of photoreactions, and \"all-things porphyrins.\" His research culminated in studies he poetically referred to as \"listening to leaves\" through the use of pulsed photoacoustic spectroscopy to probe the course and thermodynamics of photosynthesis in its native state. His research group was always small; indeed, of 185 total publications, 39 were singly authored. In brief, David Mauzerall has blended a deep knowledge of distinct disciplines of physical organic chemistry, photochemistry, spectroscopy and biophysics with ingenious experimental methods, incisive mathematical analysis, pristine personal integrity, and unyielding love of science to deepen our understanding of photosynthesis in its broadest context. He thought creatively - and always independently. His work helped systematize the fields of photosynthesis and the origin of life and made them more quantitative. The present article highlights a number of salient scientific discoveries and includes comments from members of his family, friends, and collaborators (Gary Brudvig, Greg Edens, Paul Falkowski, Alzatta Fogg, G. Govindjee, Nancy Greenbaum, Marilyn Gunner, Harvey Hou, Denise and Michele Mauzerall, Thomas Moore, and William Parson) as part of a celebration of his 95th birthday.