phenolization

酚化
  • 文章类型: Randomized Controlled Trial
    为了测试酚化在无并发症的骶尾部藏毛疾病(SPD)中的有效性和安全性,在观察性研究中,在选定的患者中,酚化在无并发症的SPD中是可行和安全的。获得最大的好处是减少病假(LSL)和并发症。单中心随机对照临床试验。患者在西班牙塔拉戈纳大学附属医院招募。将患者随机分为两个治疗组。所有无并发症骶尾部疾病的患者,位于中线,只有1个瘘口。患者被随机分配到酚化组(PhG)或常规手术组(CsG)。两组均未入院治疗。主要终点是骶尾部疾病的复发。次要终点包括病假时间,并发症,和重新接纳。124名患者被纳入研究。两组均未观察到疾病复发。进行临床随访,平均493.8天(SD6.59)。PhG的LSL较短(平均19.63天,SD28.15)比CSG(43.95天,标准差38.60)。LSL降低为-24.31天(P.002)。选定的SPD中的酚化是选定患者的安全可行的程序。这种方法可能成为选择的骶尾部藏毛患者的护理标准。
    To test the efficacy and safety of phenolization in uncomplicated Sacrococcygeal pilonidal disease (SPD) the phenolization in uncomplicated SPD is feasible and secure in selected patients in observational studies. The greatest benefits are obtained to reduce the length of sick leave (LSL) and complications. Single-center randomised controlled clinical trial. Patients were recruited at University Hospital of Tarragona Joan XXIII of Spain. Patients were randomised into two treatment groups. All patients with uncomplicated sacrococcygeal disease, localised in the midline and with only 1 fistulous orifice. The patients were randomly assigned to the phenolization group (PhG) or conventional-surgery group (CsG). Both groups were managed without admission. The main endpoint was the recurrence of sacrococcygeal disease. Secondary endpoints included time of sick leave, complications, and readmission. 124 patients were included in the study. No disease recurrence was observed in either group. Clinical follow-up was carried out with a mean of 493.8 days (SD 6.59). The LSL was shorter in the PhG (mean 19.63 days, SD 28.15) than in the CSG (43.95 days, SD 38.60). The LSL reduction was -24.31 days (P .002). The phenolization in selected SPD is a safe and feasible procedure in selected patients. This approach could become the standard of care for patients with selected Sacrococcygeal pilonidal.
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  • 文章类型: Journal Article
    背景:一些研究建议将生发基质切除术与苯酚消融联合治疗甲癣。酚化后的基质切除术已被证明是减少单独酚化相关缺点的有效方法。虽然它增加了轻微术后出血的风险。本研究旨在评估明胶海绵在酚化后部分基质切除术中作为止血剂的有效性和安全性。方法:在74例幻觉(44例)中设计了平行组的比较临床试验,II,和III型甲癣。所有参与者被随机分为3组:A组(对照组),B组(常规明胶海绵),和C组(高孔隙率明胶海绵)。结果:与对照组相比,两个实验组患者在手术后前48h的定量平均失血量均显着降低。C组(p<0.001)记录到最低的平均失血量,其次是B组(p=0.005)。实验组中的任何患者均未出现不良反应。结论:止血明胶海绵被证明是有效且安全的设备,可用于控制节段性酚醛切除术后与基质切除术相关的少量术后出血。
    Background: Some studies have recommended combining germinal matrix excision with phenol ablation in the treatment of onychocryptosis. Matrixectomy after phenolization has been shown to be an effective modification to reduce the drawbacks associated with phenolization alone, although it increases the risk of minor postoperative bleeding. The present study aims to assess the effectiveness and safety of gelatin sponges as hemostatic agents in partial matrixectomy after phenolization. Methods: A comparative clinical trial in parallel groups was designed in 74 halluces (44 patients) with stage I, II, and III onychocryptosis. All participants were randomly assigned to 3 groups: Group A (control group), Group B (conventional gelatin sponge), and Group C (high porosity gelatin sponge). Results: The quantified mean blood loss in the first 48 h after surgery in patients in both experimental groups was significantly lower compared to the control group. The lowest mean blood loss was recorded in Group C (p < 0.001) and followed by Group B (p = 0.005). No adverse effects were recorded in any of the patients included in the experimental groups. Conclusions: Hemostatic gelatin sponges were demonstrated to be effective and safe devices for the control of minor postoperative bleeding associated with matrixectomy after segmental phenolization.
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  • 文章类型: Journal Article
    OBJECTIVE: To find the recurrence and outcomes of giant cell tumors treated with scooping curettage, burr down technique, phenolization, and bone cement.
    METHODS: We conducted a descriptive case series using a non-probability consecutive sampling technique at the Department of Orthopedics, Lahore General Hospital, Lahore, Pakistan, from May 2014 to June 2018. A total of 40 patients aged between 20 to 40 years with Compannacci grade I, II & III giant cell tumors (GCT) were included and patients unfit for the surgery, those with multiple, recurrent, malignant giant cell tumors, tumors involving the axial skeleton, and previously treated cases were excluded. We recorded the side, site of the tumor, post-operative distal neurovascular status, and recurrence of giant cell tumors. The patients were follow-up in the out-patient department (OPD) at the second week, fourth week, 12th week, 24th week, 48th week, 96th week, and 144th week after the surgery. Side, site of the tumor, and post-operative distal neurovascular status were assessed clinically, and recurrence of the tumors was observed clinically and radiologically.
    RESULTS: The mean age of all patients was 25.75±5.74 years. Males were 45% (18) and females were 55% (22). Most (12, 30%) tumors were present in the upper limb, and 22 (70%) were present in the lower limb. The majority (24, 60%) tumors were present around the knee joint. Companacci grade I was five (12.5%), grade II was 14 (35%), and grade III was 21 (52%). There were six (15%) pathological fractures. There was no case of distal neurovascular (DNV) injury, and three patients had a recurrence in two years of follow-up.
    CONCLUSIONS: Giant cell tumor treated with scooping curettage, burr down technique, phenolization and poly-methyl methacrylate showed 7.5% recurrence. The combined use of local adjuvants in the treatment of giant cell tumors is a safe and effective way to reduce the rate of local recurrence.
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  • 文章类型: Journal Article
    Onychogryphosis is a disorder of nail plate growth that is clinically characterized by an opaque, yellow-brown thickening of the nail plate with associated gross hyperkeratosis, elongation, and increased curvature. It is most common in older adults and patients with poor personal care. It is a relatively common and important condition because patients may suffer from pain, secondary complications, and cosmetic concerns. We present the case of a 67-year-old man with a 30-year history of severe thickening, abnormal growth, and yellow discoloration of his left great toenail, clinically consistent with onychogryphosis. This review highlights the etiology, diagnosis, and treatment options for onychogryphosis.
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  • 文章类型: Journal Article
    The ingrown toenail is a common, painful and inflammatory clinical presentation, especially, but not exclusively, in adolescent patients. Numerous conservative treatment methods are available. Usually, however, the surgical treatment is at the end of a chain of suffering. While classified as obsolete, the so-called Emmert plasty is still used for surgical treatment. As a gentle alternative, selective treatment of the lateral matrix horn by resection or phenol caustics is increasingly used. The latter methods offer numerous benefits with little postoperative pain and faster recovery to normal quality of life.
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  • 文章类型: Journal Article
    BACKGROUND: Ingrown toenails (IT) is a very common problem leading to significant associated morbidity. The articles related to phenolization for matrix removal in teenagers with IT are not enough in the foot surgery literature.
    OBJECTIVE: To compare the postoperative recovery periods, complication rate, and tolerability of partial matrix excision and segmental phenolization in teenagers with IT.
    METHODS: Thirty-nine patients (13-17 years) with 48 IT were randomly divided into two groups and were treated with partial matrix excision (Group I) and segmental phenolization (Group II). We assessed the recurrence rates, postoperative complications, duration of analgesic usage, and time to return to daily activities.
    RESULTS: There was no significant difference between the demographic and clinical data of the two groups. Three patients in Group I and two patients in Group II experienced moderate pain postoperatively. These patients used analgesics for 3 days. The rates of postoperative complications and recurrences between the two groups showed no statistically significant difference (P = 0.688). The time to return to normal daily activities was significantly shorter in Group II patients than in Group I patients (P < 0.05).
    CONCLUSIONS: Partial matrix excision is a very safe model of therapy in the surgical treatment of teenagers with IT. It has low recurrence rate and minimal postoperative morbidity. We concluded that segmental phenolization is also as safe as partial matrix excision in the treatment of IT and patients return to their daily activities in less time with this treatment modality.
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