UNASSIGNED:理想的麻醉解决方案应提供良好的麻醉和运动不能,注射时疼痛最小。
UNASSIGNED:这项研究的目的是确定在球周麻醉期间局部麻醉混合物中碳酸氢钠相对于透明质酸酶对疼痛感知和功效的影响。
未经批准:预期,随机化,双盲研究.
UNASSIGNED:一名独立观察者将两次注射标记为A(透明质酸酶1500IU,溶于30mL利多卡因)和B(7.5%碳酸氢钠1mL,溶于30mL利多卡因)。第1组注射注射剂A,第2组注射注射剂B。视觉模拟量表(VAS)用于确定疼痛强度。记录麻醉开始和程度以及运动不能。
UNASSIGNED:使用Windows的MicrosoftExcelSPSS版本26(ChicagoInc)的计算机软件。定性数据和定量数据报告为比例和平均值±(标准偏差),分别。比例的卡方检验用于定性变量的比较,未配对的Student'st检验用于检验定量变量之间的显著性。P<0.05被认为具有统计学意义。所有P都是双尾的。
未经证实:在123名患者中,23人被排除在研究之外。将百名患者分为第1组和第2组。第1组的平均年龄为64.92±10.77岁,而第2组为62.86±11.17岁。两组的平均心率和平均收缩压均无统计学意义。与第1组(平均疼痛评分为7.16±1.09)相比,第2组经历了非常少的疼痛(平均疼痛评分VAS=5.12±1.17),并且发现两组之间的差异具有统计学意义。两组在麻醉开始方面存在显著差异(P=0.001)。在碳酸氢钠组中,发病更快。第1组(4.76±2.06分钟)的运动障碍发作较好。第1组的运动不能分级较好。
UNASSIGNED:碳酸氢钠可以减轻球周麻醉中注射时的疼痛,还可以更快地开始麻醉。
UNASSIGNED: An ideal anesthetic solution should provide good anesthesia and akinesia with minimal pain on injection.
UNASSIGNED: The aim of this study is to determine the effect on pain perception and efficacy of sodium bicarbonate over hyaluronidase in the local anesthetic mixture during peribulbar anesthesia.
UNASSIGNED: A prospective, randomized, double-blind study.
UNASSIGNED: An independent observer labeled two injections as A (hyaluronidase 1500 IU in 30 mL of lignocaine) and B (7.5% sodium bicarbonate 1 mL in 30 mL of lignocaine). Group 1 was injected with injection A while Group 2 was injected with injection B. The visual analog scale (VAS) was used to determine the intensity of pain. Onset and degree of anesthesia and akinesia were recorded.
UNASSIGNED: Computer software Microsoft Excel SPSS version 26 (Chicago Inc) for windows was used. The qualitative data and quantitative data were reported as proportions and mean ± (standard deviation), respectively. Chi-square test for proportions was used for the comparison of qualitative variables and unpaired Student\'s t-test was used to test the significance between quantitative variables. P < 0.05 was considered statistically significant. All P were two-tailed.
UNASSIGNED: Out of 123 patients, 23 were excluded from the study. Hundred patients were divided into Group 1 and Group 2. The mean age in Group 1 was 64.92 ± 10.77 years while in Group 2 was 62.86 ± 11.17 years. The mean heart rate and mean systolic blood pressure in both groups were statistically insignificant. Group 2 experienced very less pain (mean pain score VAS = 5.12 ± 1.17) as compared to Group 1 (mean pain score was 7.16 ± 1.09) and the difference between both the groups was found to be statistically significant. There was a significant difference in the onset of anesthesia in both groups (P = 0.001). In the sodium bicarbonate group, the onset was faster. The onset of akinesia was better in Group 1 (4.76 ± 2.06 min). Grading of akinesia was better in Group 1.
UNASSIGNED: Sodium bicarbonate reduces pain on injection in peribulbar anesthesia and also results in a quicker onset of anesthesia.