performance measures

绩效指标
  • 文章类型: Journal Article
    背景:临床医生需要记录数据的质量指标数量正在增加。对于许多指标,人们担心它们的功效。本研究旨在确定在重症监护病房(ICU)中仅使用基于共识的核心质量指标集是否可以减少记录ICU专业人员的绩效数据和行政负担所花费的时间。如果这与工作中更多的快乐相关,而不会影响ICU护理的质量。
    方法:在2021年5月至2023年6月之间,指示荷兰七家医院的ICU临床医生仅记录一组核心质量指标的数据。花在文档上的时间,通过经过验证的问卷,在三个时间点收集了行政负担和工作乐趣。标准化死亡率(SMR)和ICU再入院率的纵向数据来自荷兰国家重症监护登记处。对ICU之间以及护士和医生之间的纵向效果和结果差异进行了统计测试。
    结果:共390(60%),291份(47%)和236份(40%)问卷在T0、T1和T2时返回。在T2时,每天花费在文档上的总中位时间减少了30分钟(p<0.01),受访者报告的不必要和不合理的管理任务减少了(p<0.01)。几乎三分之一的人仍然经历了不必要的行政任务。随着时间的推移,在工作中没有发现快乐的显著变化,SMR和ICU再入院。
    结论:实施一套核心质量指标可减少ICU临床医生在记录和行政负担上花费的时间,而不会对SMR或ICU再入院率产生负面影响。节省时间可以投资于患者护理和提高ICU工作的乐趣。
    BACKGROUND: The number of quality indicators for which clinicians need to record data is increasing. For many indicators, there are concerns about their efficacy. This study aimed to determine whether working with only a consensus-based core set of quality indicators in the intensive care unit (ICU) reduces the time spent on documenting performance data and administrative burden of ICU professionals, and if this is associated with more joy in work without impacting the quality of ICU care.
    METHODS: Between May 2021 and June 2023, ICU clinicians of seven hospitals in the Netherlands were instructed to only document data for a core set of quality indicators. Time spent on documentation, administrative burden and joy in work were collected at three time points with validated questionnaires. Longitudinal data on standardised mortality rates (SMR) and ICU readmission rates were gathered from the Dutch National Intensive Care registry. Longitudinal effects and differences in outcomes between ICUs and between nurses and physicians were statistically tested.
    RESULTS: A total of 390 (60%), 291 (47%) and 236 (40%) questionnaires returned at T0, T1 and T2. At T2, the overall median time spent on documentation per day was halved by 30 min (p<0.01) and respondents reported fewer unnecessary and unreasonable administrative tasks (p<0.01). Almost one-third still experienced unnecessary administrative tasks. No significant changes over time were found in joy in work, SMR and ICU readmission.
    CONCLUSIONS: Implementing a core set of quality indicators reduces the time ICU clinicians spend on documentation and administrative burden without negatively affecting SMR or ICU readmission rates. Time savings can be invested in patient care and improving joy in work in the ICU.
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  • 文章类型: Journal Article
    镁合金复合材料是汽车应用的重要材料,由于其高刚度等特征,优越的阻尼电阻,高强度,和轻量级。这里,研究的目标是通过与1x105Pa真空压铸工艺相关的流体搅拌冶金路线,建立0、1、3和5体积百分比(体积%)的纳米二氧化锆(ZrO2)颗粒(50nm)的AZ91合金纳米复合材料。结构形态的暴露,硬度,和复合材料的冲击韧性进行了分析,并确定了5vol%的纳米AZ91合金复合材料是均匀的颗粒分散,增强硬度(97.6HV),最佳韧性为21.2J/mm2。然而,由于硬质磨料颗粒具有较高的硬度,复合材料面加工困难,导致工具磨损。该实验通过使用碳化钨涂层立铣刀来预测镁合金纳米复合材料(AZ91/5vol%)立铣刀操作过程中的最佳铣削参数,以获得通过通用线性模型(GLM)ANOVA方法分析的低表面粗糙度和刀具磨损的最大金属去除率。端铣操作的输入条件各不相同,像进给速度(0.1-0.4mm/转),切削深度(0.05-0.2mm),和主轴转速(250-1000rpm)。在方差分析GLM方法中,L16设计实验是固定的,用于进一步的相互作用分析。由切削深度和进给速度预测的结果占主导地位,在决定刀具磨损中起着重要作用,表面粗糙度,和MRR。
    The magnesium alloy composite is a vital material for automotive applications due to its features like high stiffness, superior damping resistance, high strength, and lightweight. Here, the motto of research is to establish the AZ91 alloy nanocomposite with the exposures of 0, 1, 3, and 5 volume percentages (vol%) of nano zirconium dioxide (ZrO2) particles (50nm) through fluid stir metallurgy route associated with 1x105 Pa vacuum die cast process. Exposures on structural morphology, hardness, and impact toughness of composite are analyzed and identified as the nano AZ91 alloy composite enclosed with 5vol% is homogenous particle dispersion, enhanced hardness (97.6HV), and optimum toughness of 21.2J/mm2. However, composite faces machining difficulties due to the hard abrasive particles with higher hardness, resulting in tool wear. This experiment predicts the optimum mill parameters during the end mill operation of magnesium alloy nanocomposite (AZ91/5vol%) by using a tungsten carbide coated end mill cutter to attain the maximum metal removal rate with low surface roughness and tool wear analyzed via the general linear model (GLM) ANOVA approach. The input conditions for end milling operation vary, like feed rate (0.1 -0.4mm/rev), depth of cut (0.05 -0.2mm), and spindle speed (250-1000rpm). During the ANOVA GLM approach, the L16 design experiment is fixed for further interaction analysis. The results predicted by the depth to cut and feed rate were dominant and played a major role in deciding the tool wear, surface roughness, and MRR.
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  • 文章类型: Journal Article
    本文件描述了适用于公开报告或按绩效付费计划的心力衰竭绩效指标,旨在作为“2020年ACC/AHA成人心力衰竭临床表现和质量指标:美国心脏病学会/美国心脏协会绩效指标工作组的报告”的重点更新。“新的绩效指标取自“2022AHA/ACC/HFSA心力衰竭管理指南:美国心脏病学会/美国心脏协会临床实践指南联合委员会的报告”,并从最强的建议(1级或3级)中选择。相比之下,质量衡量标准可能没有那么多的证据基础,通常包含的指标可能对临床医生和卫生保健组织的质量改进有用,但尚不适合公开报告或绩效付费计划.新的绩效指标包括射血分数保留的心力衰竭患者的最佳血压控制,钠-葡萄糖协同转运蛋白-2抑制剂用于射血分数降低的心力衰竭患者,以及在住院患者中使用指南指导的药物治疗。新的质量措施包括在轻度降低和保留射血分数的心力衰竭患者中使用钠-葡萄糖协同转运蛋白-2抑制剂,慢性继发性重度二尖瓣反流干预前指南指导药物治疗的优化,对射血分数改善的心力衰竭患者继续进行指南指导的药物治疗,确定心血管疾病的已知风险和健康的社会决定因素,以患者为中心的关于心肌病患者避孕和怀孕风险的咨询,以及在解释骨闪烁显像扫描评估甲状腺素运载蛋白心脏淀粉样变性时,需要进行单克隆蛋白筛选以排除轻链淀粉样变性。
    This document describes performance measures for heart failure that are appropriate for public reporting or pay-for-performance programs and is meant to serve as a focused update of the \"2020 ACC/AHA Clinical Performance and Quality Measures for Adults With Heart Failure: A Report of the American College of Cardiology/American Heart Association Task Force on Performance Measures.\" The new performance measures are taken from the \"2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines\" and are selected from the strongest recommendations (Class 1 or Class 3). In contrast, quality measures may not have as much evidence base and generally comprise metrics that might be useful for clinicians and health care organizations for quality improvement but are not yet appropriate for public reporting or pay-for-performance programs. New performance measures include optimal blood pressure control in patients with heart failure with preserved ejection fraction, the use of sodium-glucose cotransporter-2 inhibitors for patients with heart failure with reduced ejection fraction, and the use of guideline-directed medical therapy in hospitalized patients. New quality measures include the use of sodium-glucose cotransporter-2 inhibitors in patients with heart failure with mildly reduced and preserved ejection fraction, the optimization of guideline-directed medical therapy prior to intervention for chronic secondary severe mitral regurgitation, continuation of guideline-directed medical therapy for patients with heart failure with improved ejection fraction, identifying both known risks for cardiovascular disease and social determinants of health, patient-centered counseling regarding contraception and pregnancy risks for individuals with cardiomyopathy, and the need for a monoclonal protein screen to exclude light chain amyloidosis when interpreting a bone scintigraphy scan assessing for transthyretin cardiac amyloidosis.
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  • 文章类型: Journal Article
    本文件描述了适用于公开报告或按绩效付费计划的心力衰竭绩效指标,旨在作为“2020年ACC/AHA成人心力衰竭临床表现和质量指标:美国心脏病学会/美国心脏协会绩效指标工作组的报告”的重点更新。“新的绩效指标取自“2022AHA/ACC/HFSA心力衰竭管理指南:美国心脏病学会/美国心脏协会临床实践指南联合委员会的报告”,并从最强的建议(1级或3级)中选择。相比之下,质量衡量标准可能没有那么多的证据基础,通常包含的指标可能对临床医生和卫生保健组织的质量改进有用,但尚不适合公开报告或绩效付费计划.新的绩效指标包括射血分数保留的心力衰竭患者的最佳血压控制,钠-葡萄糖协同转运蛋白-2抑制剂用于射血分数降低的心力衰竭患者,以及在住院患者中使用指南指导的药物治疗。新的质量措施包括在轻度降低和保留射血分数的心力衰竭患者中使用钠-葡萄糖协同转运蛋白-2抑制剂,慢性继发性重度二尖瓣反流干预前指南指导药物治疗的优化,对射血分数改善的心力衰竭患者继续进行指南指导的药物治疗,确定心血管疾病的已知风险和健康的社会决定因素,以患者为中心的关于心肌病患者避孕和怀孕风险的咨询,以及在解释骨闪烁显像扫描评估甲状腺素运载蛋白心脏淀粉样变性时,需要进行单克隆蛋白筛选以排除轻链淀粉样变性。
    This document describes performance measures for heart failure that are appropriate for public reporting or pay-for-performance programs and is meant to serve as a focused update of the \"2020 ACC/AHA Clinical Performance and Quality Measures for Adults With Heart Failure: A Report of the American College of Cardiology/American Heart Association Task Force on Performance Measures.\" The new performance measures are taken from the \"2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines\" and are selected from the strongest recommendations (Class 1 or Class 3). In contrast, quality measures may not have as much evidence base and generally comprise metrics that might be useful for clinicians and health care organizations for quality improvement but are not yet appropriate for public reporting or pay-for-performance programs. New performance measures include optimal blood pressure control in patients with heart failure with preserved ejection fraction, the use of sodium-glucose cotransporter-2 inhibitors for patients with heart failure with reduced ejection fraction, and the use of guideline-directed medical therapy in hospitalized patients. New quality measures include the use of sodium-glucose cotransporter-2 inhibitors in patients with heart failure with mildly reduced and preserved ejection fraction, the optimization of guideline-directed medical therapy prior to intervention for chronic secondary severe mitral regurgitation, continuation of guideline-directed medical therapy for patients with heart failure with improved ejection fraction, identifying both known risks for cardiovascular disease and social determinants of health, patient-centered counseling regarding contraception and pregnancy risks for individuals with cardiomyopathy, and the need for a monoclonal protein screen to exclude light chain amyloidosis when interpreting a bone scintigraphy scan assessing for transthyretin cardiac amyloidosis.
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  • 文章类型: Journal Article
    背景:多重药房经常被用作住宅老年人护理设施(RACF)中老年人的质量指标,并使用一系列定义进行测量。数据源选择对多药率的影响以及对监测和基准的影响尚不清楚。我们旨在通过在各种情况下使用处方和管理数据来确定多药率(≥9种并发药物),利用来自30个RACF的电子数据。
    方法:对新南威尔士州5662名居民进行的纵向队列研究,澳大利亚。从2019年1月至2022年9月,每两周计算一次处方和管理的多药率,提供156次评估。使用处方和管理数据,并结合不同的项目组合,分别计算了12种不同的多药率:药物和非药物产品,四种情况下的任何药物和常规药物:不,1周,2周和4周回顾期。采用广义估计方程模型来确定处方和管理的多重用药之间差异的预测因素。
    结果:居民的综合用药率从使用无回顾期的常规药物数据的33.9%到使用处方药和非药物产品的63.5%,为期4周的回顾期。在每个评估时间,处方和给药率之间的差异一直超过10.0%,4.5%,3.5%和3.0%,分别,没有,1周,2周和4周回顾期。与同行相比,糖尿病居民面临的多重用药差异的可能性是其两倍以上,而痴呆症居民在所有分析中始终显示出降低的可能性。
    结论:我们发现处方和给药的多药率之间存在显著差异。我们建议对国家质量指标计划中计算和解释多种药物的指南进行审查,以确保一致的测量和有意义的报告。
    BACKGROUND: Polypharmacy is frequently used as a quality indicator for older adults in Residential Aged Care Facilities (RACFs) and is measured using a range of definitions. The impact of data source choice on polypharmacy rates and the implications for monitoring and benchmarking remain unclear. We aimed to determine polypharmacy rates (≥9 concurrent medicines) by using prescribed and administered data under various scenarios, leveraging electronic data from 30 RACFs.
    METHODS: A longitudinal cohort study of 5662 residents in New South Wales, Australia. Both prescribed and administered polypharmacy rates were calculated biweekly from January 2019 to September 2022, providing 156 assessment times. 12 different polypharmacy rates were computed separately using prescribing and administration data and incorporating different combinations of items: medicines and non-medicinal products, any medicines and regular medicines across four scenarios: no, 1-week, 2-week and 4-week look-back periods. Generalised estimating equation models were employed to identify predictors of discrepancies between prescribed and administered polypharmacy.
    RESULTS: Polypharmacy rates among residents ranged from 33.9% using data on administered regular medicines with no look-back period to 63.5% using prescribed medicines and non-medicinal products with a 4-week look-back period. At each assessment time, the differences between prescribed and administered polypharmacy rates were consistently more than 10.0%, 4.5%, 3.5% and 3.0%, respectively, with no, 1-week, 2-week and 4-week look-back periods. Diabetic residents faced over two times the likelihood of polypharmacy discrepancies compared with counterparts, while dementia residents consistently showed reduced likelihood across all analyses.
    CONCLUSIONS: We found notable discrepancies between polypharmacy rates for prescribed and administered medicines. We recommend a review of the guidance for calculating and interpreting polypharmacy for national quality indicator programmes to ensure consistent measurement and meaningful reporting.
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  • 文章类型: Journal Article
    背景:工作场所暴力(WPV)是医疗保健领域的一项复杂的全球挑战,只有通过由复杂的干预措施组成的质量改进计划才能解决。然而,需要多个WPV特定的质量指标来有效监测WPV并证明干预措施的影响。本研究旨在确定一套能够有效监测医疗保健中WPV的质量指标。
    方法:本研究使用改进的Delphi过程,系统地就相关WPV质量指标达成专家共识,多伦多的多站点学术健康科学中心,加拿大。专家小组由来自大学健康网络(UHN)及其附属机构的30名利益相关者组成。通过快速审查确定的相关文献质量指标根据Donabedian模型进行分类,并连续两轮Delphi提交给专家。
    结果:我们的专家小组评估了通过快速审查过程确定的87个不同的质量指标。第一轮调查的平均回复率为83.1%,第二轮为96.7%。从最初的87项质量指标来看,我们的专家小组就包括7个结构在内的17个指标达成共识,6个过程指标和4个结果指标。创建了WPV仪表板,以提供有关每个指标的实时数据。
    结论:使用改进的德尔菲方法,确定了一组由专家意见验证的质量指标,以测量UHN特有的WPV。本研究中确定的指标被发现在UHN可操作,并将提供纵向质量监测。他们将为数据可视化和传播工具提供信息,这些工具将实时影响组织决策。
    BACKGROUND: Workplace violence (WPV) is a complex global challenge in healthcare that can only be addressed through a quality improvement initiative composed of a complex intervention. However, multiple WPV-specific quality indicators are required to effectively monitor WPV and demonstrate an intervention\'s impact. This study aims to determine a set of quality indicators capable of effectively monitoring WPV in healthcare.
    METHODS: This study used a modified Delphi process to systematically arrive at an expert consensus on relevant WPV quality indicators at a large, multisite academic health science centre in Toronto, Canada. The expert panel consisted of 30 stakeholders from the University Health Network (UHN) and its affiliates. Relevant literature-based quality indicators which had been identified through a rapid review were categorised according to the Donabedian model and presented to experts for two consecutive Delphi rounds.
    RESULTS: 87 distinct quality indicators identified through the rapid review process were assessed by our expert panel. The surveys received an average response rate of 83.1% in the first round and 96.7% in the second round. From the initial set of 87 quality indicators, our expert panel arrived at a consensus on 17 indicators including 7 structure, 6 process and 4 outcome indicators. A WPV dashboard was created to provide real-time data on each of these indicators.
    CONCLUSIONS: Using a modified Delphi methodology, a set of quality indicators validated by expert opinion was identified measuring WPV specific to UHN. The indicators identified in this study were found to be operationalisable at UHN and will provide longitudinal quality monitoring. They will inform data visualisation and dissemination tools which will impact organisational decision-making in real time.
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  • 文章类型: Journal Article
    背景:正在探索医院发病的菌血症和真菌血症(HOB)作为监测和质量指标。本研究的目的是确定美国住院患者HOB的来源和可预防性,并确定与感知的可预防性相关的因素。
    方法:我们对10家学术医院和3家社区医院的HOB事件进行了横断面研究。HOB定义为在医院第4天或之后具有一种或多种细菌或真菌生物体生长的血液培养物。HOB事件按共生和非共生生物分层。住院医师,传染病研究员或感染预防专家查看图表以确定HOB来源,在感染预防/医院流行病学培训的传染病医生使用结构化指南将可预防性评分从1到6(1=绝对可预防到6=绝对不可预防)。等级1-3被统称为“潜在可预防”和4-6“潜在不可预防”。
    结果:在非共生生物的1789个HOB事件中,胃肠道(包括中性粒细胞减少)(35%)和血管内(32%)是最常见的来源.总的来说,636/1789(36%)非共生和238/320(74%)共生HOB事件被认为是可以预防的。在非共生HOB事件之间的逻辑回归分析中,血管内导管相关感染事件,留置导尿管相关感染和手术部位感染被评为可预防的几率较高,而中性粒细胞减少的事件,免疫抑制,胃肠道来源,同一入院的多微生物培养和先前的阳性血培养被评为可预防的几率较低,与没有这些属性的事件进行比较。在636起可能可预防的非共生HOB事件中,47%是血管内起源,其次是胃肠道,呼吸道和尿源;大约40%的这些事件不会通过现有的医疗保健相关感染监测来捕获。
    结论:应使用与较高或较低可预防性相关的因素来指导纳入。与HOB相关的质量指标的排除和风险调整。
    BACKGROUND: Hospital-onset bacteraemia and fungaemia (HOB) is being explored as a surveillance and quality metric. The objectives of the current study were to determine sources and preventability of HOB in hospitalised patients in the USA and to identify factors associated with perceived preventability.
    METHODS: We conducted a cross-sectional study of HOB events at 10 academic and three community hospitals using structured chart review. HOB was defined as a blood culture on or after hospital day 4 with growth of one or more bacterial or fungal organisms. HOB events were stratified by commensal and non-commensal organisms. Medical resident physicians, infectious disease fellows or infection preventionists reviewed charts to determine HOB source, and infectious disease physicians with training in infection prevention/hospital epidemiology rated preventability from 1 to 6 (1=definitely preventable to 6=definitely not preventable) using a structured guide. Ratings of 1-3 were collectively considered \'potentially preventable\' and 4-6 \'potentially not preventable\'.
    RESULTS: Among 1789 HOB events with non-commensal organisms, gastrointestinal (including neutropenic translocation) (35%) and endovascular (32%) were the most common sources. Overall, 636/1789 (36%) non-commensal and 238/320 (74%) commensal HOB events were rated potentially preventable. In logistic regression analysis among non-commensal HOB events, events attributed to intravascular catheter-related infection, indwelling urinary catheter-related infection and surgical site infection had higher odds of being rated preventable while events with neutropenia, immunosuppression, gastrointestinal sources, polymicrobial cultures and previous positive blood culture in the same admission had lower odds of being rated preventable, compared with events without those attributes. Of 636 potentially preventable non-commensal HOB events, 47% were endovascular in origin, followed by gastrointestinal, respiratory and urinary sources; approximately 40% of those events would not be captured through existing healthcare-associated infection surveillance.
    CONCLUSIONS: Factors identified as associated with higher or lower preventability should be used to guide inclusion, exclusion and risk adjustment for an HOB-related quality metric.
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  • 文章类型: Journal Article
    直接面向消费者的远程医疗(DTCT)已成为传统护理的替代方案。然而,与缺乏综合质量评价相关的潜在风险的不确定性可能会影响其长期发展。这项研究旨在评估中国DTCT平台在2021年7月至2022年1月期间使用未通知的标准化患者(USP)提供的护理质量。该研究使用医学质量研究所框架评估了医院和企业赞助平台上的咨询服务。它雇用了10个USP案例,包括糖尿病等疾病,哮喘,普通感冒,胃炎,心绞痛,腰痛,儿童腹泻,儿童皮炎,压力性尿失禁和产后抑郁症。采用描述性和回归分析来检查平台特征并比较不同平台类型的质量。结果显示,在107个不同的远程医疗平台上的170次USP访问中,企业赞助的平台在访问方面取得了100%的成功,而医院赞助的平台的成功率仅为47.5%(56/118)。分析强调了45%的总体正确诊断率低,并且在所有平台上对临床指南的依从性不足。值得注意的是,企业赞助的平台在可访问性方面表现出色,与医院赞助平台相比,响应时间和病例管理。这项研究突出了中国DTCT平台的质量次优,特别是医院赞助的平台。为了进一步加强DTCT服务,未来的研究应该比较DTCT和亲自护理,旨在确定与使用DTCT作为传统护理的替代或补充相关的差距和潜在风险。增强DTCT服务的未来发展潜力可能涉及探索医院资源与企业赞助平台的技术和市场能力的整合。
    Direct-to-onsumer telemedicine (DTCT) has become popular as an alternative to traditional care. However, uncertainties about the potential risks associated with the lack of comprehensive quality evaluation could influence its long-term development. This study aimed to assess the quality of care provided by DTCT platforms in China using unannounced standardised patients (USP) between July 2021 and January 2022. The study assessed consultation services on both hospital and enterprise-sponsored platforms using the Institute of Medicine quality framework. It employed 10 USP cases, covering conditions such as diabetes, asthma, common cold, gastritis, angina, low back pain, child diarrhoea, child dermatitis, stress urinary incontinence and postpartum depression. Descriptive and regression analyses were employed to examine platform characteristics and compare quality across platform types. The results showed that of 170 USP visits across 107 different telemedicine platforms, enterprise-sponsored platforms achieved a 100% success in access, while hospital-sponsored platforms had a success rate of only 47.5% (56/118). Analysis highlighted a low overall correct diagnosis rate of 45% and inadequate adherence to clinical guidelines across all platforms. Notably, enterprise-sponsored platforms outperformed in accessibility, response time and case management compared with hospital-sponsored platforms. This study highlights the suboptimal quality of DTCT platforms in China, particularly for hospital-sponsored platforms. To further enhance DTCT services, future studies should compare DTCT and in-person care, aiming to identify gaps and potential risks associated with using DTCT as alternatives or supplements to traditional care. The potential of future development in enhancing DTCT services may involve exploring the integration of hospital resources with the technology and market capabilities of enterprise-sponsored platforms.
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  • 文章类型: Journal Article
    背景:尽管缺乏改善预后的证据,但心脏麻醉医师仍在围手术期常规使用白蛋白。多中心围手术期结果组(MPOG)数据将我们的机构列为心脏手术期间术中白蛋白使用者最高的机构之一。因此,我们设计了一个质量改进项目(QIP),引入了一系列干预措施,以减少心脏外科手术患者术中白蛋白的使用.
    方法:我们的机构MPOG数据用于分析FLUID-01-C测量,该测量提供了从2019年7月1日至2022年6月30日由麻醉师术中给予白蛋白的成人心脏手术病例数。QIP包括引入以下干预措施:(1)有关适当白蛋白使用和适应症的教育(2021年1月),(2)通过OR教学加强电子邮件通信(2021年3月),(3)从标准药房术中用药托盘中取出白蛋白(2021年4月),(4)讨论QIP并强调干预措施的大轮演示(2021年5月)和(5)季度提供商反馈(从2021年7月开始)。多变量分段回归模型用于评估白蛋白利用从干预前到干预后时间段的变化,以及每月的总成本。
    结果:在3年研究期间,5767例符合纳入标准的心脏手术病例中,16%的患者术中接受白蛋白。通过度量的病例总数(避免了白蛋白管理),随着我们的干预措施生效,逐渐增加。术中白蛋白利用率(β=-101.1,95%CI-145至-56.7)和白蛋白的月总费用(β=-7678,95%CI-10712至-4640)在开始干预后显示出显着下降。
    结论:在一个单一的学术心脏手术项目中,作为协调QIP的一部分,实施一系列简单且低成本的干预措施可有效减少术中白蛋白的使用,这转化为可观的成本节约。
    BACKGROUND: Albumin continues to be used routinely by cardiac anaesthesiologists perioperatively despite lack of evidence for improved outcomes. The Multicenter Perioperative Outcomes Group (MPOG) data ranked our institution as one of the highest intraoperative albumin users during cardiac surgery. Therefore, we designed a quality improvement project (QIP) to introduce a bundle of interventions to reduce intraoperative albumin use in cardiac surgical patients.
    METHODS: Our institutional MPOG data were used to analyse the FLUID-01-C measure that provides the number of adult cardiac surgery cases where albumin was administered intraoperatively by anaesthesiologists from 1 July 2019 to 30 June 2022. The QIP involved introduction of the following interventions: (1) education about appropriate albumin use and indications (January 2021), (2) email communications reinforced with OR teaching (March 2021), (3) removal of albumin from the standard pharmacy intraoperative medication trays (April 2021), (4) grand rounds presentation discussing the QIP and highlighting the interventions (May 2021) and (5) quarterly provider feedback (starting July 2021). Multivariable segmented regression models were used to assess the changes from preintervention to postintervention time period in albumin utilisation, and its total monthly cost.
    RESULTS: Among the 5767 cardiac surgery cases that met inclusion criteria over the 3-year study period, 16% of patients received albumin intraoperatively. The total number of cases that passed the metric (albumin administration was avoided), gradually increased as our interventions went into effect. Intraoperative albumin utilisation (beta=-101.1, 95% CI -145 to -56.7) and total monthly cost of albumin (beta=-7678, 95% CI -10712 to -4640) demonstrated significant decrease after starting the interventions.
    CONCLUSIONS: At a single academic cardiac surgery programme, implementation of a bundle of simple and low-cost interventions as part of a coordinated QIP were effective in significantly decreasing intraoperative use of albumin, which translated into considerable costs savings.
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  • 文章类型: Journal Article
    大宗商品等另类资产是否提高了投资组合的多样化?经验证据一般是积极的,但喜忧参半,几乎只关注美国的数据。使用1993-2019年期间的几个不同的商品指数,我们调查了加拿大投资者的案例,一个商品货币国家,股票已经受到商品贝塔系数的影响。我们对厌恶风险和厌恶失望的投资者都使用了跨越测试和几个样本外的绩效指标。总的来说,我们发现,虽然在金融化之前和期间,加拿大商品的多样化潜力有限,后金融化时期提供了新的机遇。证据表明,使用一些,但不是全部,商品指数。因此,选择相关商品指数作为多样化的工具很重要。最后,将国际组成部分与投资组合的行业多样化相结合可以显著提高其绩效。
    Do alternative assets such as commodities improve portfolio diversification? The empirical evidence is generally positive but mixed, and almost exclusively focuses on U.S. data. Using several distinct commodity indexes over the period 1993-2019, we investigate the case of an investor in Canada, a commodity-currency country where equities are already exposed to commodity beta. We use spanning tests and several out-of-sample performance measures for both risk-averse and disappointment-averse investors. Overall, we find that while the diversification potential of commodities was limited in Canada before and during financialization, the post-financialization period offers new opportunities. The evidence suggests that portfolio performance is significantly improved using some, but not all, commodity indexes. Thus, the choice of a relevant commodity index matters as a vehicle for diversification. Finally, compounding an international component to the sectorial diversification of the portfolio can significantly improve its performance.
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