pelvimetry

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  • 文章类型: Journal Article
    背景:Türkiye是在绵羊育种方面排名世界的国家。哈姆达尼杂交绵羊品种是适应我国艰苦条件的绵羊品种之一。此外,这句话可以被纠正为“特别是在蒂尔基耶的东南部,杂交育种是育种者的首选,以提高绵羊的产量特性。
    目的:在我们的研究中,目的是通过三维建模方法对中期和中期的Hamdani杂交绵羊胎儿进行盆栽分析。
    方法:为此,共有40个中期妊娠(10名女性,10名男性)和孕晚期(10名女性,使用10只雄性)胎儿。胎儿的骨盆用CT成像并创建3D模型。从模型中进行了16次骨盆测量。对获得的结果进行统计学评价。
    结果:研究发现,在妊娠中期,男性和女性胎儿在垂直直径(VD)和闭孔宽度(FOW)测量参数方面存在统计学上的显着差异。在妊娠晚期,髋臼(AC)性别间差异有统计学意义(p<0.01),坐骨内侧结节(MIT),和坐骨弓(IA)(p<0.05)参数。作为相关性分析的结果,确定骨盆长度(PL)测量参数在两个时期都与不同参数呈不同程度的正相关,而IA参数在妊娠的最后两个时期与其他参数没有显着相关性。
    结论:结论:获得的数据将有助于人类和动物胎儿的骨盆测量评估,解剖学教育,动物考古学和分类学研究。
    BACKGROUND: Türkiye is a country in the world ranking in terms of sheep breeding. Hamdani crossbred sheep breed is one of the sheep breeds that can adapt to the difficult conditions in our country. In addition, the sentence may be corrected as \'Especially in the southeastern part of the Türkiye, crossbreeding is preferred by breeders to increase the yield characteristics of sheep\'.
    OBJECTIVE: In our study, it was aimed to perform a pelvimetric analysis of Hamdani crossbred sheep fetuses in the second and third trimesters by three-dimensional modelling method.
    METHODS: For this purpose, a total of 40 second-trimester (10 females, 10 males) and third-trimester (10 females, 10 males) fetuses were used. The pelvises of the fetuses were imaged with CT and 3D models were created. Sixteen pelvimetric measurements were performed from the models. The results obtained were evaluated statistically.
    RESULTS: The study found statistically significant differences between male and female fetuses in terms of vertical diameter (VD) and foramen obturatum width (FOW) measurement parameters in the second trimester. In the third trimester, there were statistically significant differences between genders in acetabulum (AC) (p < 0.01), medial ischial tuberosities (MIT), and ischiatic arch (IA) (p < 0.05) parameters. As a result of the correlation analysis, it was determined that the pelvis length (PL) measurement parameter was positively correlated with different parameters in varying degrees in both periods, while the IA parameter did not show significant correlations with the other parameter in the last two periods of pregnancy.
    CONCLUSIONS: In conclusion, the data obtained will be useful in pelvimetric evaluations of human and animal fetuses, anatomy education, zooarchaeology and taxonomy studies.
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  • 文章类型: Journal Article
    很少有研究检查骨盆大小与剖宫产(TOLAC)后分娩试验成败之间的关系。在这里,我们旨在确定从X射线照相术获得的骨盆大小和形态数据是否有助于首次成功的TOLAC。这项回顾性单中心观察研究招募了2010年至2021年接受TOLAC的孕妇。X射线骨盆测量数据的结果,包括产科共轭(OC),骨盆入口的横向直径(TD),骨盆入口前后径(APD),骨盆入口的形状,和其他产科临床数据,在成功组和失败组之间进行了比较。在排除35例先前成功的TOLAC患者后,成功组的75例患者,失败组21例患者符合条件。由于分娩试验失败(p=0.042)和新生儿体重较重(p=0.014),失败组先前的剖宫产率较高。OC,TD,两组的X线骨盆测量和APD没有显着差异,骨盆入口的形状也没有影响TOLAC的成功率。广义线性模型确定了劳动试验失败的历史,作为TOLAC失败的重要预测因子(赔率比,0.26;95%置信区间0.071-0.923;p=0.037),而没有发现骨盆参数。盆腔大小和形态学发现对TOLAC的结果没有明显影响。在所有尝试TOLAC的女性中普遍应用X射线骨盆测定法可能没有明显的临床意义。
    Few studies have examined the relationship between pelvic size and the success or failure of trial of labor after cesarean delivery (TOLAC). Here we aimed to determine whether pelvic size and morphological data obtained from radiography contribute to the first successful TOLAC. This retrospective single-center observational study enrolled pregnant women who underwent TOLAC between 2010 and 2021. The results of X-ray pelvimetry data, including obstetric conjugate (OC), transverse diameter of the pelvic inlet (TD), anteroposterior diameter of the pelvic inlet (APD), shape of the pelvic inlet, and other obstetrical clinical data, were compared between the success and failure groups. Seventy-five patients in successful group after excluding 35 patients with previous successful TOLAC, and 21 patients in failure group were eligible. The failure group had a higher rate of previous cesarean sections due to failed labor trials (p = 0.042) and heavier newborns (p = 0.014). OC, TD, and APD on X-ray pelvimetry did not differ significantly between the two groups nor did the shape of the pelvic inlet affect the success rate for TOLAC. The generalized linear model identified a history of failed trials of labor as a significant predictor of failed TOLAC (odds ratio, 0.26; 95% confidence interval 0.071-0.923; p = 0.037), whereas no pelvimetric parameters were found. Pelvic size and morphological findings have no discernible impact on the outcomes of TOLAC. The universal application of X-ray pelvimetry in all women attempting TOLAC may not have significant clinical relevance.
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  • 文章类型: Journal Article
    目的:本研究的目的是调查使用原始放射摄影Martius图像和应用高通滤波的相同图像(“边缘图像”)的骨盆测量结果是否一致。
    方法:本研究共纳入了30只原虫。三名产科医生独立测量了原始图像和边缘图像中骨盆入口的前后直径和横向直径,记录四个端点的x和y坐标。对坐标数据进行Wilcoxon符号秩和检验,以评估原始图像和边缘图像之间的差异。
    结果:在对所有坐标数据的分析中,骶骨隆起点(SPP)的x坐标和y坐标均存在统计学上的显着差异。在SPP的y坐标中,在30对图像中的9对中发现了统计学上的显着差异,与原始图像相比,在所有9个图像中,由于SPP的尾部位置更多,因此边缘图像的前后直径较短。
    结论:在使用Martius图像的骨盆测量中,原始X射线照片及其边缘图像上的SPP坐标不一致。我们的结果表明,改善的图像对比度将使产科医生更好地评估骨盆狭窄和头骨盆比例不均,甚至减少射线照相剂量,从而降低孕妇及其胎儿的风险。
    OBJECTIVE: The aim of this study is to investigate whether the results of pelvimetry using original radiographic Martius images and the same images with high-pass filtering applied (\"edge images\") would be consistent.
    METHODS: A total of 30 primagravidas were included in this study. Three obstetricians independently measured the anteroposterior and transverse diameters of the pelvic inlet in the original and the edge images, recording the x- and y-coordinates of the four endpoints. A Wilcoxon signed rank sum test was performed on the coordinate data to evaluate differences between the original and edge images.
    RESULTS: In the analysis of all coordinate data, statistically significant differences were found in both x- and y-coordinates of the sacral promontory point (SPP). In the y-coordinate of the SPP, a statistically significant difference was found in 9 of 30 pairs of images, and in all 9 the anteroposterior diameter was shorter in the edge images compared to the original images due to the more caudal placement of the SPP.
    CONCLUSIONS: The coordinates of the SPP on original radiographs and their edge images were not consistent in pelvimetry using Martius images. Our results suggest that improved image contrast will allow obstetricians to better assess pelvic narrowing and cephalopelvic disproportion and even reduce radiographic dose, thereby reducing risks for pregnant women and their fetuses.
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  • 文章类型: Journal Article
    人类青少年和成人骨骼在骨盆中表现出性二态性。然而,产前发育过程中人类骨盆的性二态性程度尚不清楚.这里,我们对72例人类胎儿进行了高分辨率磁共振成像辅助骨盆测量(男性[M]:女性[F],34:38;21个部位),冠部-臀部长度(CRL)为50-225mm(原发性骨化开始)。我们使用多元回归分析以CRL为协变量来检验性二态性。雌性表现出明显较小的骨盆入口前后直径(最小二乘平均值,[F]8.4mmvs.[M]8.8毫米,P=0.036),较大的耻骨下角([F]68.1°vs.[M]64.0°,P=0.034),与男性相比,相对于较大骨盆的横向直径,坐骨棘之间的距离更大。此外,骶骨测量表明显著的性别-CRL相互作用。我们的研究表明,在原发性骨化开始时,人类胎儿骨盆的性二态性已经很明显。
    Human adolescent and adult skeletons exhibit sexual dimorphism in the pelvis. However, the degree of sexual dimorphism of the human pelvis during prenatal development remains unclear. Here, we performed high-resolution magnetic resonance imaging-assisted pelvimetry on 72 human fetuses (males [M]: females [F], 34:38; 21 sites) with crown-rump lengths (CRL) of 50-225 mm (the onset of primary ossification). We used multiple regression analysis to examine sexual dimorphism with CRL as a covariate. Females exhibit significantly smaller pelvic inlet anteroposterior diameters (least squares mean, [F] 8.4 mm vs. [M] 8.8 mm, P = 0.036), larger subpubic angle ([F] 68.1° vs. [M] 64.0°, P = 0.034), and larger distance between the ischial spines relative to the transverse diameters of the greater pelvis than males. Furthermore, the sacral measurements indicate significant sex-CRL interactions. Our study suggests that sexual dimorphism of the human fetal pelvis is already apparent at the onset of primary ossification.
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  • 文章类型: Journal Article
    背景:腹腔镜直肠癌根治术是一项受多种因素影响的复杂手术。然而,现有文献缺乏骨盆区域和软组织的标准化参数,这阻碍了一致结论的建立。
    目的:通过基于计算机断层扫描(CT)的三维(3D)重建,全面评估16个骨盆和7个软组织参数,为解决腹腔镜直肠癌根治术的挑战提供了有力的理论依据。
    方法:我们分析了218例接受腹腔镜直肠癌根治术的患者的数据,并利用CT数据进行3D骨盆重建。使用先进的3D建模软件仔细标记和测量特定的解剖点。分析骨盆和软组织参数,我们采用了包括配对样本t检验在内的统计方法,Wilcoxon秩和检验,和相关分析。
    结果:调查强调了14个骨盆骨参数和3个软组织参数的显著性别差异。男性在骨盆深度和整体曲率方面表现出较大的测量值,骨盆宽度测量较小,更大的直肠系膜脂肪面积,和较大的前后腹部直径。相比之下,女性表现出更宽的骨盆,较浅的深度,较小的整体曲率,皮下脂肪组织数量增加.然而,在某些参数(如骶骨弯曲高度)中没有观察到显著的性别差异,耻骨尾骨上直径,直肠面积,内脏脂肪面积,腰围,和横向腹部直径。
    结论:3DCT数据的重建可以实现准确的骨盆测量,揭示了骨盆和软组织参数的显着性别差异。这项研究设计为预测手术困难和为男性直肠癌患者制定个性化的手术计划提供了潜在的“骨盆困难”,最终改善手术结果。对这些参数的进一步研究和利用可能会导致腹腔镜直肠癌根治术中手术方法和患者护理的增强。
    BACKGROUND: Laparoscopic rectal cancer radical surgery is a complex procedure affected by various factors. However, the existing literature lacks standardized parameters for the pelvic region and soft tissues, which hampers the establishment of consistent conclusions.
    OBJECTIVE: To comprehensively assess 16 pelvic and 7 soft tissue parameters through computerized tomography (CT)-based three-dimensional (3D) reconstruction, providing a strong theoretical basis to address challenges in laparoscopic rectal cancer radical surgery.
    METHODS: We analyzed data from 218 patients who underwent radical laparoscopic surgery for rectal cancer, and utilized CT data for 3D pelvic reconstruction. Specific anatomical points were carefully marked and measured using advanced 3D modeling software. To analyze the pelvic and soft tissue parameters, we employed statistical methods including paired sample t-tests, Wilcoxon rank-sum tests, and correlation analysis.
    RESULTS: The investigation highlighted significant sex disparities in 14 pelvic bone parameters and 3 soft tissue parameters. Males demonstrated larger measurements in pelvic depth and overall curvature, smaller measurements in pelvic width, a larger mesorectal fat area, and a larger anterior-posterior abdominal diameter. By contrast, females exhibited wider pelvises, shallower depth, smaller overall curvature, and an increased amount of subcutaneous fat tissue. However, there were no significant sex differences observed in certain parameters such as sacral curvature height, superior pubococcygeal diameter, rectal area, visceral fat area, waist circumference, and transverse abdominal diameter.
    CONCLUSIONS: The reconstruction of 3D CT data enabled accurate pelvic measurements, revealing significant sex differences in both pelvic and soft tissue parameters. This study design offer potential in predicting surgical difficulties and creating personalized surgical plans for male rectal cancer patients with a potentially \"difficult pelvis\", ultimately improving surgical outcomes. Further research and utilization of these parameters could lead to enhanced surgical methods and patient care in laparoscopic rectal cancer radical surgery.
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  • 文章类型: Journal Article
    目的:本研究探讨了机器人辅助低位和超低低位前切除术的困难因素,专注于骨盆解剖的简单测量。
    方法:回顾性分析2018年10月至2023年4月期间接受机器人辅助低位和超低位直肠癌前切除术的61例患者的临床资料。盆腔期手术时间与临床病理资料的关系,尤其是在X射线和计算机断层扫描(CT)上测量的骨盆解剖参数,进行了评估。骨盆期的手术时间定义为从the角动员到直肠切除之间的时间。
    结果:在32和29例患者中进行了机器人辅助的低位和超低低位前切除术,分别。骨盆期的中位手术时间为126(范围,31-332)分钟。多元线性回归分析表明,从肛门边缘到下边缘的短距离,一个狭窄的区域,包括髂骨的线,骨盆前后和横向直径较短,盆腔直肠系膜的小角度与盆腔期手术时间延长有关。
    结论:使用腹部X线摄影和CT进行简单的骨盆解剖测量可以预测机器人辅助直肠癌手术的骨盆操作时间。
    OBJECTIVE: This study explored the difficulty factors in robot-assisted low and ultra-low anterior resection, focusing on simple measurements of the pelvic anatomy.
    METHODS: This was a retrospective analysis of the clinical data of 61 patients who underwent robot-assisted low and ultra-low anterior resection for rectal cancer between October 2018 and April 2023. The relationship between the operative time in the pelvic phase and clinicopathological data, especially pelvic anatomical parameters measured on X-ray and computed tomography (CT), was evaluated. The operative time in the pelvic phase was defined as the time between mobilization from the sacral promontory and rectal resection.
    RESULTS: Robot-assisted low and ultra-low anterior resections were performed in 32 and 29 patients, respectively. The median operative time in the pelvic phase was 126 (range, 31-332) min. A multiple linear regression analysis showed that a short distance from the anal verge to the lower edge of the cancer, a narrow area comprising the iliopectineal line, short anteroposterior and transverse pelvic diameters, and a small angle of the pelvic mesorectum were associated with a prolonged operative time in the pelvic phase.
    CONCLUSIONS: Simple pelvic anatomical measurements using abdominal radiography and CT may predict the pelvic manipulation time in robot-assisted surgery for rectal cancer.
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  • 文章类型: Journal Article
    背景:完整的全直肠系膜切除术是治愈性直肠癌手术的金标准。确保质量在狭窄的骨盆中具有挑战性,肥胖会放大技术难题。骨盆测量是测量骨盆尺寸,但是它在评估直肠切除术前难度中的作用在很大程度上尚未被探索。
    目的:确定与根治性直肠切除术后不完全全直肠系膜切除术相关的盆腔结构因素,并建立全直肠系膜切除术质量的预测模型。
    方法:回顾性队列研究。
    方法:诊断为直肠腺癌的患者的四级转诊中心数据库(2009-2017)。
    方法:直肠腺癌的治疗性直肠切除术。
    方法:所有放射学测量值都是使用经过验证的图像处理软件工具从术前CT图像获得的。从组织学报告中获得全直肠系膜切除术的完整性。
    方法:放射骨盆测量和肥胖测量预测全直肠系膜切除质量的能力。
    结果:在符合纳入标准的410例病例中,362个完整的全直肠系膜切除(88%)。多变量回归确定了更深的骶骨曲线(每100mm2[OR:1.14,95%CI:1.06-1.23,p<0.001]),盆腔出口的横向距离(每10mm[OR:1.41,95%CI:1.08-1.84,p=0.012])与不完全的全直肠系膜切除术独立相关。骨盆入口面积增加(每10cm2);OR:0.85,[95%CI:0.75-0.97,p=0.02]与更高的完整直肠系膜切除术率相关。内脏肥胖比率和内脏肥胖比率无差异(比率>0.4与<0.4)之间的体重指数(<30vs.≥30)或性别已确定。使用变量:骶骨曲线深度,骨盆入口面积和骨盆出口横向距离。
    结论:回顾性分析未对手术方式的选择进行控制。
    结论:骨盆法可以预测直肠癌手术中的全直肠系膜切除质量,并且可以在术前提醒外科医生注意异常困难的情况。这种预测模型可能有助于治疗策略,并有助于比较传统和新技术的全直肠系膜切除术的结果。请参见视频摘要。
    BACKGROUND: A complete total mesorectal excision is the criterion standard in curative rectal cancer surgery. Ensuring quality is challenging in a narrow pelvis, and obesity amplifies technical difficulties. Pelvimetry is the measurement of pelvic dimensions, but its role in gauging preoperatively the difficulty of proctectomy is largely unexplored.
    OBJECTIVE: To determine pelvic structural factors associated with incomplete total mesorectal excision after curative proctectomy and build a predictive model for total mesorectal excision quality.
    METHODS: Retrospective cohort study.
    METHODS: A quaternary referral center database of patients diagnosed with rectal adenocarcinoma (2009-2017).
    METHODS: Curative-intent proctectomy for rectal adenocarcinoma.
    METHODS: All radiological measurements were obtained from preoperative CT images using validated imaging processing software tools. Completeness of total mesorectal excision was obtained from histology reports.
    METHODS: Ability of radiological pelvimetry and obesity measurements to predict total mesorectal excision quality.
    RESULTS: Of the 410 cases meeting inclusion criteria, 362 underwent a complete total mesorectal excision (88%). Multivariable regression identified a deeper sacral curve (per 100 mm 2 [OR: 1.14; 95% CI, 1.06-1.23; p < 0.001]) and a greater transverse distance of the pelvic outlet (per 10 mm [OR:1.41, 95% CI, 1.08-1.84; p = 0.012]) to be independently associated with incomplete total mesorectal excision. An increased area of the pelvic inlet (per 10 cm 2 [OR: 0.85; 95% CI, 0.75-0.97; p = 0.02) was associated with a higher rate of complete mesorectal excision. No difference in visceral obesity ratio and visceral obesity (ratio >0.4 vs <0.4) between BMI (<30 vs ≥30) and sex was identified. A model was built to predict mesorectal quality using the following variables: depth of sacral curve, area of pelvic inlet, and transverse distance of the pelvic outlet.
    CONCLUSIONS: Retrospective analysis is not controlled for the choice of surgical approach.
    CONCLUSIONS: Pelvimetry predicts total mesorectal excision quality in rectal cancer surgery and can alert surgeons preoperatively to cases of unusual difficulty. This predictive model may contribute to treatment strategy and aid in the comparison of outcomes between traditional and novel techniques of total mesorectal excision. See Video Abstract .
    UNASSIGNED: ANTECEDENTES:Una escisión mesorrectal total y completa es el estándar de oro en la cirugía curativa del cáncer de recto. Garantizar la calidad es un desafío en una pelvis estrecha y la obesidad amplifica las dificultades técnicas. La pelvimetría es la medición de las dimensiones pélvicas, pero su papel para medir la dificultad preoperatoria de la proctectomía está en gran medida inexplorado.OBJETIVO:Determinar los factores estructurales pélvicos asociados con la escisión mesorrectal total incompleta después de una proctectomía curativa y construir un modelo predictivo para la calidad de la escisión mesorrectal total.DISEÑO:Estudio de cohorte retrospectivo.ÁMBITO:Base de datos de un centro de referencia cuaternario de pacientes diagnosticados con adenocarcinoma de recto (2009-2017).PACIENTES:Proctectomía con intención curativa para adenocarcinoma de recto.INTERVENCIONES:Todas las mediciones radiológicas se obtuvieron a partir de imágenes de TC preoperatorias utilizando herramientas de software de procesamiento de imágenes validadas. La integridad de la escisión mesorrectal total se obtuvo a partir de informes histológicos.PRINCIPALES MEDIDAS DE VALORACIÓN:Capacidad de la pelvimetría radiológica y las mediciones de obesidad para predecir la calidad total de la escisión mesorrectal.RESULTADOS:De los 410 casos que cumplieron los criterios de inclusión, 362 tuvieron una escisión mesorrectal total completa (88%). Una regresión multivariable identificó una curva sacra más profunda (por 100 mm2); OR:1,14,[IC95%:1,06-1,23,p<0,001], y mayor distancia transversal de salida pélvica (por 10mm); OR:1,41, [IC 95%:1,08-1,84,p=0,012] como asociación independiente con escisión mesorrectal total incompleta. Un área aumentada de entrada pélvica (por 10 cm2); OR:0,85, [IC95%:0,75-0,97,p=0,02] se asoció con una mayor tasa de escisión mesorrectal completa. No se identificaron diferencias en la proporción de obesidad visceral y la obesidad visceral (proporción>0,4 vs.<0,4) entre el índice de masa corporal (<30 vs.>=30) o el sexo. Se construyó un modelo para predecir la calidad mesorrectal utilizando variables: profundidad de la curva sacra, área de la entrada pélvica y distancia transversal de la salida pélvica.LIMITACIONES:Análisis retrospectivo no controlado por la elección del abordaje quirúrgico.CONCLUSIONES:La pelvimetría predice la calidad de la escisión mesorrectal total en la cirugía del cáncer de recto y puede alertar a los cirujanos preoperatoriamente sobre casos de dificultad inusual. Este modelo predictivo puede contribuir a la estrategia de tratamiento y ayudar en la comparación de resultados entre técnicas tradicionales y novedosas de escisión mesorrectal total. (Traducción- Dr. Ingrid Melo).
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  • 文章类型: Journal Article
    目的:比较骨盆测量中基于磁共振成像(MRI)的3D模型和基于计算机断层扫描(CT)的3D模型。
    方法:回顾性分析2009年12月至2020年10月行盆腔3DMRI和3DCT骨盆测量的141例妇科疾病患者。两种骨盆测量方法通过配对学生t检验进行比较,皮尔逊相关系数,Bland-Altman分析和组内相关系数(ICC)。
    结果:每种直径的方法之间的差异具有统计学意义,除骨盆入口后矢状直径(t:-0.71,P=0.5)和骨盆前后出口直径(t:0.02,P=0.98)外。3DMRI和3DCT骨盆测量具有很强的相关性(r:min0.7,max:0.96,P<0.01)。Bland-Altman结果表明,每个骨盆直径线的差异点大于95%,在95%的一致性范围内。对于使用两个读取器之间的MRI-3D(ICC:0.64-0.98)或CT-3D(ICC:0.72-0.98)的所有骨盆测量,ICC良好到非常好。
    结论:3DMRI和3DCT骨盆测量具有良好的一致性和可重复性,表明3DMRI对于骨盆测量是可靠的。
    OBJECTIVE: To compare 3D models based on magnetic resonance imaging (MRI) and 3D models based on computed tomography (CT) in pelvimetry.
    METHODS: A retrospective analysis of 141 patients who underwent both pelvic 3D MRI and 3D CT pelvimetry for gynecological diseases from December 2009 to October 2020 was performed. The two pelvimetry methods were compared by paired Student\'s t test, Pearson\'s correlation coefficient, Bland-Altman analysis and intraclass correlation coefficient (ICC).
    RESULTS: The differences between methods for each diameter were statistically significant, except for those of the posterior sagittal diameter of the pelvic inlet (t:-0.71, P = 0.5) and the anteroposterior pelvic outlet diameter (t:0.02, P = 0.98). 3D MRI and 3D CT pelvimetry strongly correlated with each other (r: min 0.7, max: 0.96, P < 0.01). The Bland-Altman results indicate that the difference points of each pelvic diameter line greater than 95 % are within the 95 % limits of agreement. The ICC was good to very good for all pelvimetric measurements using either MRI-3D (ICC: 0.64-0.98) or CT-3D (ICC: 0.72-0.98) between the two readers.
    CONCLUSIONS: 3D MRI and 3D CT pelvimetry have good agreement and reproducibility, indicating that 3D MRI is reliable for pelvimetry.
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  • 文章类型: Journal Article
    腹腔镜全直肠系膜切除术(LaTME)是直肠癌的标准手术方法,和LaTME操作是一个具有挑战性的程序。这项研究旨在使用机器学习来开发和验证直肠癌患者LaTME手术难度的预测模型,并比较这些模型的性能。
    我们回顾性收集了2017年至2022年接受腹腔镜全直肠系膜切除术的直肠癌患者的术前临床和MRI骨盆参数。根据Escal报告的评分标准定义LaTME的难度。患者随机分为训练组(80%)和试验组(20%)。我们使用最小绝对收缩和选择算子(LASSO)和多变量逻辑回归方法选择了独立的影响特征。采用合成少数过采样技术(SMOTE)来缓解类不平衡问题。开发了六种机器学习模型:光梯度增强机(LGBM);分类增强(CatBoost);极端梯度增强(XGBoost),逻辑回归(LR);随机森林(RF);多层感知器(MLP)。受试者工作特征曲线下面积(AUROC),准确度,灵敏度,特异性和F1评分用于评估模型的性能.Shapley加法解释(SHAP)分析为最佳机器学习模型提供了解释。进一步的决策曲线分析(DCA)用于评价模型的临床表现。
    共纳入626例患者。LASSO回归分析显示肿瘤高度,预后营养指数(PNI),骨盆入口,骨盆出口,骶尾部距离,直肠系膜脂肪面积和角度5(骶骨角顶点与耻骨下缘之间的夹角)是机器学习模型的预测变量。此外,相关热图显示,这七个变量之间没有显著的相关性。在预测LaTME手术的难度时,XGBoost模型在六个机器学习模型中表现最好(AUROC=0.855)。根据决策曲线分析(DCA)结果,XGBoost模型也是优越的,特征重要性分析表明,肿瘤高度是7个因素中最重要的变量。
    这项研究开发了XGBoost模型来预测LaTME手术的难度。该模型可以帮助临床医生快速准确地预测手术难度,采用个体化的手术方法。
    UNASSIGNED: Laparoscopic total mesorectal excision (LaTME) is standard surgical methods for rectal cancer, and LaTME operation is a challenging procedure. This study is intended to use machine learning to develop and validate prediction models for surgical difficulty of LaTME in patients with rectal cancer and compare these models\' performance.
    UNASSIGNED: We retrospectively collected the preoperative clinical and MRI pelvimetry parameter of rectal cancer patients who underwent laparoscopic total mesorectal resection from 2017 to 2022. The difficulty of LaTME was defined according to the scoring criteria reported by Escal. Patients were randomly divided into training group (80%) and test group (20%). We selected independent influencing features using the least absolute shrinkage and selection operator (LASSO) and multivariate logistic regression method. Adopt synthetic minority oversampling technique (SMOTE) to alleviate the class imbalance problem. Six machine learning model were developed: light gradient boosting machine (LGBM); categorical boosting (CatBoost); extreme gradient boost (XGBoost), logistic regression (LR); random forests (RF); multilayer perceptron (MLP). The area under receiver operating characteristic curve (AUROC), accuracy, sensitivity, specificity and F1 score were used to evaluate the performance of the model. The Shapley Additive Explanations (SHAP) analysis provided interpretation for the best machine learning model. Further decision curve analysis (DCA) was used to evaluate the clinical manifestations of the model.
    UNASSIGNED: A total of 626 patients were included. LASSO regression analysis shows that tumor height, prognostic nutrition index (PNI), pelvic inlet, pelvic outlet, sacrococcygeal distance, mesorectal fat area and angle 5 (the angle between the apex of the sacral angle and the lower edge of the pubic bone) are the predictor variables of the machine learning model. In addition, the correlation heatmap shows that there is no significant correlation between these seven variables. When predicting the difficulty of LaTME surgery, the XGBoost model performed best among the six machine learning models (AUROC=0.855). Based on the decision curve analysis (DCA) results, the XGBoost model is also superior, and feature importance analysis shows that tumor height is the most important variable among the seven factors.
    UNASSIGNED: This study developed an XGBoost model to predict the difficulty of LaTME surgery. This model can help clinicians quickly and accurately predict the difficulty of surgery and adopt individualized surgical methods.
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  • 文章类型: Journal Article
    (1)背景:盆腔形态对产科决策具有重要意义。这项研究旨在评估放射科医生在三维(3D)骨盆模型上手动标记解剖标志时获得的骨盆测量的准确性和可靠性。第二个目标是设计一种自动标记方法。(2)方法:3位操作者各分割10次计算机断层扫描。然后,三名放射科医生在骨盆模型上标记了12个解剖标志,这允许计算15项骨盆测量。此外,基于参考骨盆模型开发了一种自动标记方法,包括参考解剖标志,匹配各个骨盆模型。(3)结果:观察到放射科医生标记准确性中标志之间的异质性,一些地标很少被错误标记超过4毫米,而另一些则经常被错误标记10毫米或更多。向骨盆测量的传播是有限的;15项测量中只有一项报告中值误差超过5毫米或5°,所有措施都显示出中等至优秀的放射科医师间可靠性。自动方法优于手动标记。(4)结论:这项研究证实了基于3D骨盆模型的手动标记的骨盆测量措施的适用性。自动标签提供了有希望的观点,以减少对放射科医生的需求,标准化标签,并更详细地描述盆腔。
    (1) Background: The morphology of the pelvic cavity is important for decision-making in obstetrics. This study aimed to estimate the accuracy and reliability of pelvimetry measures obtained when radiologists manually label anatomical landmarks on three-dimensional (3D) pelvic models. A second objective was to design an automatic labeling method. (2) Methods: Three operators segmented 10 computed tomography scans each. Three radiologists then labeled 12 anatomical landmarks on the pelvic models, which allowed for the calculation of 15 pelvimetry measures. Additionally, an automatic labeling method was developed based on a reference pelvic model, including reference anatomical landmarks, matching the individual pelvic models. (3) Results: Heterogeneity among landmarks in radiologists\' labeling accuracy was observed, with some landmarks being rarely mislabeled by more than 4 mm and others being frequently mislabeled by 10 mm or more. The propagation to the pelvimetry measures was limited; only one out of the 15 measures reported a median error above 5 mm or 5°, and all measures showed moderate to excellent inter-radiologist reliability. The automatic method outperformed manual labeling. (4) Conclusions: This study confirmed the suitability of pelvimetry measures based on manual labeling of 3D pelvic models. Automatic labeling offers promising perspectives to decrease the demand on radiologists, standardize the labeling, and describe the pelvic cavity in more detail.
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