目的:评估对Samoyed幼犬(6-14周龄)进行的房角镜检查是否是成年(>11月龄)的可靠预测结果。
方法:进行了回顾性医疗记录搜索,以确定曾接受房角镜检查的Samoyed犬为小狗(6-14周龄)。作为成年人(>11个月大)进行第二次前瞻性房角镜检查,并比较结果。根据两个特征评估房角镜检查:不受果胶韧带异常(PLA)和ICA宽度影响的虹膜角膜角(ICA)百分比,PLA结果分类为未受影响(≥$$\\ge$$75%开放),中度影响(50%-74%开放),和严重影响(<50%开放)和宽度分类为宽,中度,狭窄,封闭的团体。创建了一个多变量模型,考虑了PLA、角宽度,性别,小狗的年龄,中性状态,和考试之间的时间。
结果:77只Samoyed犬(154只眼)的眼睛符合纳入标准。在评估PLA时,90%的狗与小狗和成年狗具有相同的分类。评估ICA宽度时,53.2%的狗具有与小狗和成年狗相同的宽度分类。有强有力的证据表明,小狗和成年结果之间的差异随着检查之间的时间而增加(p=0.03)。
结论:幼犬不受PLA影响,具有宽ICA角,作为成年人,可能会保留这些特征。选择具有理想性腺性状的幼犬可能有助于育种者选择可能保留这些性状的狗作为成年繁殖。这可以减少该品种中青光眼的发病率。应该在双眼中进行小狗检查。在繁殖之前对成年人进行检查仍然是谨慎的。
OBJECTIVE: To assess whether gonioscopy performed on Samoyed puppies (6-14 weeks of age) is a reliable predictor of their gonioscopy results as adults (>11 months of age).
METHODS: A retrospective medical record search was performed to identify Samoyed dogs that had undergone gonioscopy as a puppy (6-14 weeks of age). A second prospective gonioscopy examination was performed as an adult (>11 months of age) and the results were compared. Gonioscopy was assessed on two characteristics: percent of iridocorneal angle (ICA) unaffected by pectinate ligament abnormalities (PLA) and ICA width, with PLA results categorized into unaffected ( ≥ 75% open), moderately affected (50%-74% open), and severely affected (<50% open) and the width categorized into wide, moderate, narrow, and closed groups. A multivariate model was created that considered factors such as PLA, angle width, sex, puppy age, neuter status, and time between examinations.
RESULTS: The eyes of 77 Samoyed dogs (154 eyes) met inclusion criteria. When assessing PLA, 90% of dogs had the same categorization as a puppy and as an adult. When assessing ICA width, 53.2% of dogs had the same width classification as a puppy and as an adult. There is strong evidence that variation between puppy and adult results increases with time between examination (p = .03).
CONCLUSIONS: Puppies unaffected by PLA and with a wide ICA angle, are likely to retain these features as adults. Selection of puppies with desirable gonioscopic traits may help breeders to choose dogs likely to retain these traits as adults for breeding. This may reduce the incidence of glaucoma in the breed. Puppy examinations should be performed in both eyes. Examination of adults prior to breeding remains prudent.