palliative care consultation

  • 文章类型: Journal Article
    背景:鉴于胶质母细胞瘤的典型轨迹,随着时间的推移,许多患者失去了决策能力,这可能导致不充分的预先护理计划(ACP)和临终护理(EOL)。我们旨在评估患者目前的ACP和EOL护理状态。
    方法:我们在2017年至2022年间对韩国三级医院的205名肿瘤学家进行了队列研究。我们收集了有关社会人口因素的信息,癌症治疗,姑息治疗咨询,ACP,关于维持生命治疗(LST)决定的法律文件,和EOL护理的侵略性。
    结果:中位随访时间18.3个月:159例患者死亡;中位总生存期:20.3个月。159名患者中,11个(6.9%)和63个(39.6%)有预先指令(AD)和LST计划,分别,而85(53.5%)两者都没有。在有LST计划的63人中,10人(15.9%)和53人(84.1%)通过自决和家庭决定完成了他们的表格,分别。死亡的159名患者中,102例(64.2%)接受了姑息治疗咨询(中位时间:从第一次咨询到死亡的44天),78例(49.1%)接受了积极的EOL治疗。那些接受姑息治疗咨询的人不太可能接受积极的EOL护理(83.3%vs32.4%,P<.001),更有可能在EOL使用超过3天的临终关怀(19.6%vs68.0%,P<.001)。
    结论:胶质母细胞瘤患者的自决权保护仍然很差,近90%的人没有自我完成AD或LST计划。由于姑息治疗咨询与不那么积极的EOL护理和更长时间使用临终关怀相关,医师应及时向患者介绍ACP对话和姑息治疗咨询.
    BACKGROUND: Given the typical trajectory of glioblastoma, many patients lose decision-making capacity over time, which can lead to inadequate advance care planning (ACP) and end-of-life (EOL) care. We aimed to evaluate patients\' current ACP and EOL care status.
    METHODS: We conducted a cohort study on 205 patients referred to oncologists at a Korean tertiary hospital between 2017 and 2022. We collected information on sociodemographic factors, cancer treatment, palliative care consultation, ACP, legal documents on life-sustaining treatment (LST) decisions, and aggressiveness of EOL care.
    RESULTS: With a median follow-up time of 18.3 months: 159 patients died; median overall survival: 20.3 months. Of the 159 patients, 11 (6.9%) and 63 (39.6%) had advance directive (AD) and LST plans, respectively, whereas 85 (53.5%) had neither. Among the 63 with LST plans, 10 (15.9%) and 53 (84.1%) completed their forms through self-determination and family determination, respectively. Of the 159 patients who died, 102 (64.2%) received palliative care consultation (median time: 44 days from the first consultation to death) and 78 (49.1%) received aggressive EOL care. Those receiving palliative care consultations were less likely to receive aggressive EOL care (83.3% vs 32.4%, P < .001), and more likely to use more than 3 days of hospice care at EOL (19.6% vs 68.0%, P < .001).
    CONCLUSIONS: The right to self-determination remains poorly protected among patients with glioblastoma, with nearly 90% not self-completing AD or LST plan. As palliative care consultation is associated with less aggressive EOL care and longer use of hospice care, physicians should promptly introduce patients to ACP conversations and palliative care consultations.
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  • 文章类型: Journal Article
    手术干预在重症老年患者中很常见,近三分之一的美国老年人在生命的最后一年面临手术。尽管在接受高风险外科手术的老年手术患者中,姑息治疗具有潜在的益处,该人群的姑息治疗未得到充分利用,对种族/民族的潜在差异以及虚弱如何影响这种差异知之甚少。这项研究的目的是检查种族/民族在姑息治疗咨询中的差异,并评估患者的虚弱是否减轻了这种联系。利用2005年至2019年医疗保健成本和利用项目的全国住院患者样本对住院手术发作进行的回顾性横断面研究,我们发现体弱的黑人患者接受姑息治疗咨询的次数最少,以黑人-亚洲/太平洋岛民体弱患者为代表的最大组间调整后差异为1.6个百分点,控制社会人口统计学,合并症,医院特色,程序类型,和年份。在非虚弱患者中,接受姑息治疗咨询的种族/种族差异未观察到。这些发现表明,为了改善接受高风险外科手术的虚弱老年患者的种族/族裔差异,姑息治疗咨询应作为临床护理指南中的标准护理.
    Surgical interventions are common among seriously ill older patients, with nearly one-third of older Americans facing surgery in their last year of life. Despite the potential benefits of palliative care among older surgical patients undergoing high-risk surgical procedures, palliative care in this population is underutilized and little is known about potential disparities by race/ethnicity and how frailty my affect such disparities. The aim of this study was to examine disparities in palliative care consultations by race/ethnicity and assess whether patients\' frailty moderated this association. Drawing on a retrospective cross-sectional study of inpatient surgical episodes using the National Inpatient Sample of the Healthcare Cost and Utilization Project from 2005 to 2019, we found that frail Black patients received palliative care consultations least often, with the largest between-group adjusted difference represented by Black-Asian/Pacific Islander frail patients of 1.6 percentage points, controlling for sociodemographic, comorbidities, hospital characteristics, procedure type, and year. No racial/ethnic difference in the receipt of palliative care consultations was observed among nonfrail patients. These findings suggest that, in order to improve racial/ethnic disparities in frail older patients undergoing high-risk surgical procedures, palliative care consultations should be included as the standard of care in clinical care guidelines.
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  • 文章类型: Letter
    暂无摘要。
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  • 文章类型: Journal Article
    2019年冠状病毒病(COVID-19)大流行导致生命终结时复杂的身体和心理社会症状负担。在其他疾病状态下,专家姑息治疗投入的好处已经确立,然而,几乎没有证据表明,在死于COVID-19的患者中,这些服务的转诊模式。
    这项回顾性审计调查了2022年在南澳大利亚一家四级医院(皇家阿德莱德医院)死于COVID-19的患者的转诊模式,以及人口统计学特征或COVID-19特定因素是否对这些患者是否接受专科姑息治疗服务(PCS)产生影响。第二个目标是确定患者生命最后24小时的处方模式,以及这是否受到转诊的影响。
    数据是从电子病历中获得的,并根据各种预测因素,使用二元逻辑回归分析转诊至PCS与不转诊。
    患者人口统计学或COVID-19特异性因素与转诊PCS相比没有显着差异。死亡前24小时接受转诊的患者与口服吗啡等效日剂量(OMEDD)较高的患者之间有统计学意义。以及持续皮下输注的存在。尽管这种关系的原因尚不确定,它可能代表了姑息治疗医师在会诊期间的处方模式,或提示转诊的潜在更高的症状负担.与其他阿片类药物相比,接受氢吗啡酮的患者比例也更高,尽管OMEDD与其他已发表的文献一致。
    UNASSIGNED: The coronavirus disease 2019 (COVID-19) pandemic resulted in complex physical and psychosocial symptom burden at end of life. The benefit of specialist palliative care input in other disease states has been established, however, there is little evidence on referral patterns to these services in patients dying from COVID-19.
    UNASSIGNED: This retrospective audit investigated the referral patterns for patients who died from COVID-19 at a quaternary hospital in South Australia (the Royal Adelaide Hospital) over a six-month period in 2022, and whether demographic features or COVID-19 specific factors had an impact on whether these patients received specialist palliative care services (PCS). The second aim was to identify prescription patterns for patients in the last 24 hours of life, and whether this was impacted by referral.
    UNASSIGNED: Data were obtained from electronic medical records and analyzed using binary logistic regressions for referral to PCS versus no referral based on various predictors.
    UNASSIGNED: There was no significant difference comparing patient demographics or COVID-19 specific factors with referral to PCS. There was statistical significance between patients who received referral to PCS and those who had a higher oral morphine equivalent daily dose (OMEDD) in the 24 hours before death, as well as the presence of a continuous subcutaneous infusion. Although the cause of this relationship is undetermined, it may represent the prescription patterns of the palliative care physicians during consultation or potentially higher symptom burden prompting referral. There was also a higher proportion of patients who received hydromorphone compared with other opioids, though the OMEDD was consistent with other published literature.
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  • 文章类型: Journal Article
    背景:终末期肝病患者症状负担高,医疗保健利用率高,这可以通过姑息治疗咨询来改善。目标:我们试图确定在终末期肝病住院患者中实施标准化姑息治疗咨询标准是否会增加姑息治疗利用率并改善患者预后。方法:我们对终末期肝病住院患者进行了回顾性队列研究。18岁以下的患者接受了先前的肝移植,或接受肝移植不包括在内。符合以下两个或多个标准的终末期肝病患者包括:(i)ChildPughC肝硬化,(ii)在6个月内2次或2次以上肝脏相关住院,(iii)目前酒精使用与酒精性肝硬化,和(iv)不适合移植工作。我们比较了标准实施前后的咨询情况,我们比较了接受过姑息治疗和未接受过姑息治疗的患者的结局.结果:随着实施,咨询增加(2/25(8%)对11/33(33%),p=.020)。姑息治疗与医疗保健代表文件的完成率更高相关(66.7%vs35.7%,P=.20)和医生对治疗形式范围的命令(16.7%vs0%,P=0.13)。姑息治疗的患者临终关怀出院率较高(30.8%vs0,P=0.002)。结论:对终末期肝病患者实施规范化姑息治疗咨询标准可提高姑息治疗的利用率。姑息治疗所看到的患者在临终关怀服务中的出院率增加,并且高级指令的完成率有提高的趋势。
    Context: Patients with end-stage liver disease have high symptom burden and high healthcare utilization, which may be improved by palliative care consultation. Objectives: We sought to determine if implementing standardized palliative care consultation criteria in hospitalized patients with end-stage liver disease would increase palliative care utilization and improve patient outcomes. Methods: We conducted a retrospective cohort study of hospitalized patients with end-stage liver disease. Patients under the age of 18, received a previous liver transplant, or admitted for liver transplantation were not included. Patients with end-stage liver disease meeting two or more of the following criteria were included: (i)Child Pugh C cirrhosis, (ii)2 or more liver related hospitalizations within 6 months, (iii) current alcohol use with alcoholic cirrhosis, and (iv) unsuitable for transplantation work up. We compared consults before and after implementation of the criteria, and we compared outcomes in patients who did and did not see palliative care. Results: With implementation, consults increased (2/25 (8%) vs 11/33 (33%), p = .020). Palliative care was associated with higher completion of health care representative documentation (66.7% vs 35.7%, P = .20) and physician orders for scope of treatment forms (16.7% vs 0%, P = 0.13). Patients seen by palliative care had a higher rate of discharges with hospice (30.8% vs 0, P = .002). Conclusions: Implementation of standardized palliative care consultation criteria for patients with end-stage liver disease increased palliative care utilization. Patients seen by palliative care had increased discharges with hospice services and a trend towards higher completion rates of advanced directives.
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  • 文章类型: Journal Article
    背景:姑息治疗旨在改善晚期疾病(AI)患者的预后。倡导使其成为AI住院患者主流护理的一部分。
    目的:确定医院医学与专业姑息治疗之间的合作是否会增加对需要姑息治疗的AI患者的识别。次要结果:减少30天的再入院,住院时间(LOS)和疼痛评分,增加反映目标和先进护理计划的文件。
    方法:对入住住院医师-住院医师运行单位的AI患者进行回顾性图表回顾,分为护理模式,\"A\"和\"B,“并分析了两个十个月的时间,\"1\"和\"2。\"为\"A提供了姑息需求的触发器。\"在双周取整期间,需求被评估和通才与专家级别的姑息治疗概念用于咨询.
    方法:纽约都会区第四纪教学中心。
    方法:对3395例AI患者进行分析,1707来自“1”,1688来自“2”。\"
    结果:比较护理模式和时间框架,姑息治疗咨询在“A”中增加(P值=.0013,P值=.0005)。调查\"1\"至\"2中的\"A\"时,\"CMI较高。在“1”和“2”之间比较“B”,发现年龄较大,LACE较低。当调整混杂因素(LACE和CMI)时,我们的模型没有显示出差异。关于亚急性康复的出院处置数据具有重要意义,但对死亡率没有影响。次要结局的护理模式和时间段之间没有差异。
    结论:我们的研究表明了对姑息治疗服务纳入医院医学的需求,并强调了未来研究的重点领域。
    BACKGROUND: Palliative care seeks to improve outcomes for patients with advanced illness (AI). Advocacy exists for making it part of mainstream care for hospitalized patients with AI.
    OBJECTIVE: To determine if a partnership between hospital-medicine and specialized palliative care would increase identification of AI patients with palliative care needs requiring palliative consultation. Secondary outcomes: Decreasing 30-day readmission, length of stay (LOS) and pain scores, increasing documentation reflecting goals and advanced care planning.
    METHODS: Retrospective chart review of patients with AI admitted to a hospitalist-resident run unit divided into Care Models, \"A\" and \"B,\" and analyzed over two ten-month periods, \"1\" and \"2.\" Triggers for palliative needs were provided for \"A.\" During biweekly rounding, needs were assessed and generalist vs. specialist level palliative care concepts were used for consultation.
    METHODS: Quaternary-level teaching center in the New York Metropolitan area.
    METHODS: 3,395 AI patients were analyzed, 1,707 from \"1,\" and 1,688 from \"2.\"
    RESULTS: Comparing care models and time frames, palliative care consultation increased in \"A\" (P-value = .0013, P-value = .0005). When investigating \"A\" in \"1\" to \"2,\" CMI was higher. Comparing \"B\" between \"1\" and \"2,\" found older age and lower LACE. When adjusting for confounders (LACE and CMI), our models did not show a difference. Data on discharge disposition was significant for subacute rehab but not for mortality. There were no differences between care models and time-periods for secondary outcomes.
    CONCLUSIONS: Our study demonstrated the demand for palliative care services integrated into hospital medicine and highlighted areas of focus for future studies.
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  • 文章类型: Journal Article
    随着我们日益老龄化的住院人口的复杂性,我们对住院医师实施了跨专业的老年和姑息治疗干预.本研究旨在衡量干预措施对住院时间(LOS)的影响,重新接纳30天,以及住院服务利用的每日强度。
    在拥有1000张床位的美国四级学术医学中心使用非随机对照干预措施,我们研究了13,941名接受普通医学医院服务的患者(其中5644人年龄>=65岁);1483人在干预小组中(576人年龄>=65岁),5413个并发控制,和7045个历史控件。在11个医院团队中的2个中,一个老年病学家,姑息治疗医生和社会工作者每周两次参加多学科出院检查,建议住院老年或姑息治疗咨询(GPCC),急性护理或家庭护理,与出院后门诊咨询相比。我们测量了以下干预组和对照组患者随时间的改善差异:(1)根据病例组合指数调整的LOS,(2)30天再入院,和(3)医院服务利用强度(每位患者每天提供的平均服务)。
    干预组1483名患者的调整后LOS(住院天数)减少了0.36天(p=0.039),在576例老年患者中,每次入院的LOS平均减少0.55天(p=0.022)。再入院率没有变化(-1.17%,所有患者p=0.48;1.91%,老年患者的p=0.46)。然而,每日相对价值单位(RVU)利用率在整体和较老的亚组都略有增加,干预团队平均每患者日0.35个RVU(p=0.041)和0.74个RVU(p<0.001),分别。
    与医院服务机构合作的老年和姑息治疗咨询的跨专业干预可能会降低LOS,特别是对于老年病人,而不会增加再入院。该模型可能对医院护理具有更广泛的意义,应进一步研究。
    With increasing complexity of our aging inpatient population, we implemented an interprofessional geriatric and palliative care intervention on a hospitalist service. This study aimed to measure the intervention\'s impact on length of stay (LOS), 30-day readmission, and the daily intensity of inpatient services utilization.
    Using a nonrandomized controlled intervention at a 1000-bed U.S. academic quaternary medical center, we studied 13,941 individuals admitted to a general medicine hospitalist service (of which 5644 were age > =65 years); 1483 were on intervention teams (576 age > =65 years), 5413 concurrent controls, and 7045 historical controls. On 2 of 11 hospitalist teams, a geriatrician, palliative care physician and social worker attended multidisciplinary discharge rounds twice weekly, to recommend inpatient geriatric or palliative care consult (GPCC), postacute nursing or home care, versus postdischarge outpatient consultation. We measured the difference in improvement over time between intervention and control team patients for the following: (1) LOS adjusted for case-mix index, (2) 30-day readmissions, and (3) intensity of hospital service utilization (mean services provided per patient per day).
    Adjusted LOS (in hospital days) was decreased by 0.36 days (p = 0.039) for the 1483 patients in the intervention teams, with greater LOS reduction of 0.55 days per admission (p = 0.022) on average among the subset of 576 older patient admissions. Readmissions were unchanged (-1.17%, p = 0.48 for all patients; 1.91%, p = 0.46 for older patients). However, the daily relative value unit (RVU) utilization was modestly increased for both the overall and older subgroup, 0.35 RVUs (p = 0.041) and 0.74 RVUs (p < 0.001) per patient-day on average across the intervention teams, respectively.
    An interprofessional intervention of geriatric and palliative care consultation in collaboration with a hospitalist service may reduce LOS, especially for geriatric patients, without an increase in readmissions. This model may have broader implications for hospital care and should be further studied.
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  • 文章类型: Journal Article
    左心室辅助装置(LVAD)是晚期心力衰竭(HF)管理的重要组成部分,作为移植或目的地治疗的桥梁。晚期HF患者预后不良,可能受益于姑息治疗咨询(PCC)。然而,关于接受LVAD植入的患者中PCC的趋势和预测因素的数据很少.
    本研究旨在评估发病率,趋势,使用2006年至2014年的美国全国住院患者样本(NIS)数据库,以及LVAD接受者中PCC的预测因素。
    我们在住院期间对LVAD受者进行了加权分析。我们比较了那些有PCC的人和没有的人。我们检查了姑息治疗利用的趋势,并计算了调整后的优势比(aOR),以确定人口统计学,社会,使用多变量逻辑回归分析和与PCC相关的医院特征。
    我们确定了20,675名接受LVAD植入的患者,其中4%有PCC。PCC年率从0.6%上升到7.2%(P<0.001)。DNR状态(aOR28.30),女性(AOR1.41),转移癌(AOR:3.53),Midwestlocation(aOR1.33),小型医院(aOR2.52)是PCC和院内并发症的阳性预测因子.不同的是,黑人(aOR0.43)和西班牙裔患者(aOR0.25)不太可能接受PCC。
    在LVAD入院中,院内PCC转诊有增加的趋势,而总体比率仍然很低。这些发现表明,需要在晚期HF患者中早期使用PCC的综合模型来提高其普遍利用率。
    UNASSIGNED: Left ventricular assist devices (LVADs) are an essential part of advanced heart failure (HF) management, either as a bridge to transplantation or destination therapy. Patients with advanced HF have a poor prognosis and may benefit from palliative care consultation (PCC). However, there is scarce data regarding the trends and predictors of PCC among patients undergoing LVAD implantation.
    UNASSIGNED: This study aims to assess the incidence, trends, and predictors of PCC in LVAD recipients using the United States Nationwide Inpatient Sample (NIS) database from 2006 until 2014.
    UNASSIGNED: We conducted a weighted analysis on LVAD recipients during their index hospitalization. We compared those who had PCC with those who did not. We examined the trend in palliative care utilization and calculated adjusted odds ratios (aOR) to identify demographic, social, and hospital characteristics associated with PCC using multivariable logistic regression analysis.
    UNASSIGNED: We identified 20,675 admissions who had LVAD implantation, and of them 4% had PCC. PCC yearly rate increased from 0.6% to 7.2% (P < 0.001). DNR status (aOR 28.30), female sex (aOR 1.41), metastatic cancer (aOR: 3.53), Midwest location (aOR 1.33), and small-sized hospitals (aOR 2.52) were positive predictors for PCC along with in-hospital complications. Differently, Black (aOR 0.43) and Hispanic patients (aOR 0.25) were less likely to receive PCC.
    UNASSIGNED: There was an increasing trend for in-hospital PCC referral in LVAD admissions while the overall rate remained low. These findings suggest that integrative models to involve PCC early in advanced HF patients are needed to increase its generalized utilization.
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  • 文章类型: Journal Article
    姑息治疗咨询已显示出在多种疾病中的益处,但在金黄色葡萄球菌菌血症患者中的效用仍不清楚,尽管其死亡率高。
    研究美国金黄色葡萄球菌菌血症患者姑息治疗咨询的频率和与姑息治疗咨询相关的因素。
    2014年使用全国住院患者样本数据库进行的基于人群的回顾性分析,由医疗保健研究和质量机构的医疗保健成本和利用项目编制。
    所有出院诊断为金黄色葡萄球菌菌血症的住院患者(ICD-9-CM代码;038.11和038.12)。
    姑息治疗咨询使用ICD-9-CM代码V66.7确定。比较有和没有姑息治疗咨询的患者的基线特征和结果。
    2014年共发现111,320例金黄色葡萄球菌菌血症入院。在8140例住院患者中观察到姑息治疗咨询(7.3%)。姑息治疗咨询与高龄有关,白人种族,合并症,更高的收入,教学/城市医院,中西部地区,耐甲氧西林金黄色葡萄球菌菌血症和超声心动图缺乏。姑息治疗咨询也与更短但更昂贵的住院有关。接受姑息治疗咨询的患者的粗死亡率为53%(4314/8140),未接受姑息治疗咨询的患者为8%(8357/10,3180)(p<0.001)。
    在处理金黄色葡萄球菌菌血症期间,姑息治疗咨询很少见,大量患者在没有姑息治疗咨询的情况下住院期间死亡。鉴于报告的其他医疗条件的好处,姑息治疗咨询可能在金黄色葡萄球菌菌血症中发挥作用。应该探索选择可能受益最大的患者。
    Palliative care consultation has shown benefits across a wide spectrum of diseases, but the utility in patients with Staphylococcus aureus bacteremia remains unclear despite its high mortality.
    To examine the frequency of palliative care consultation and factors associated with palliative care consult in Staphylococcus aureus bacteremia patients in the United States.
    A population-based retrospective analysis using the Nationwide Inpatient Sample database in 2014, compiled by the Healthcare Costs and Utilization Project of the Agency for Healthcare Research and Quality.
    All inpatients with a discharge diagnosis of Staphylococcus aureus bacteremia (ICD-9-CM codes; 038.11 and 038.12).
    Palliative care consultation was identified using ICD-9-CM code V66.7. Patients\' baseline characteristics and outcomes were compared between those with and without palliative care consult.
    A total of 111,320 Staphylococcus aureus bacteremia admissions were identified in 2014. Palliative care consult was observed in 8140 admissions (7.3%). Palliative care consultation was associated with advanced age, white race, comorbidities, higher income, teaching/urban hospitals, Midwest region, Methicillin-resistant Staphylococcus aureus bacteremia and the lack of echocardiogram. Palliative care consult was also associated with shorter but more expensive hospitalizations. Crude mortality was 53% (4314/8140) among admissions with palliative care consult and 8% (8357/10,3180) among those without palliative care consult (p < 0.001).
    Palliative care consultation was infrequent during the management of Staphylococcus aureus bacteremia, and a substantial number of patients died during their hospitalizations without palliative care consult. Given the reported benefit in other medical conditions, palliative care consultation may have a role in Staphylococcus aureus bacteremia. Selecting patients who may benefit the most should be explored.
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  • 文章类型: Journal Article
    Objective To explore the effects of palliative care consultation on medical professionals who have requested it in Peking Union Medical College Hospital. Methods Semi-structured interviews were conducted with 17 medical professionals who had requested palliative care consultation.Results Palliative care consultation had the following positive effects:building a bridge for doctor-patient communication,providing psychological support to reduce the sense of occupational exhaustion for medical professionals,providing technical support for medical professionals to help patients relieve symptoms,helping medical professionals in the multidisciplinary learning of palliative care,adding humanistic care and neglected ethical concerns.Conclusion Palliative care consultation improves the quality of care for dying patients,and the capacity of consultation needs to be enhanced urgently.
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