不孕症,影响全球众多夫妇的广泛医疗状况,尽管辅助生殖技术(ART)取得了进展,但仍然是一个挑战,经常被财政负担,物理,和情绪紧张。补充和替代方法,尤其是瑜伽,已经引起了人们的关注,有可能提高生育结果。研究揭示了瑜伽对导致不孕的因素的影响,包括降低氧化应激(OS)和氧化性DNA损伤(ODD)。操作系统,与诱变碱基形成有关,较高的丙二醛水平,异常甲基化,改变了基因表达,会损害精子基因组的完整性。瑜伽的功效在降低OS方面很明显,积极影响信号传输,基因表达,和生理系统。此外,瑜伽对解决细胞凋亡失调有积极的影响,导致精子发生等过程的改善,精子成熟,和运动性,同时也减少了DNA片段化。OS与全基因组低甲基化相关,端粒缩短,和线粒体功能障碍,导致基因组不稳定。瑜伽和冥想显著减少OS和ODD,确保适当的活性氧水平和保持生理系统。这篇综述探讨了瑜伽对不孕症的积极影响的潜在机制,包括增强血流,减少炎症,松弛反应,和调节下丘脑-垂体-肾上腺轴。此外,对文献的全面回顾显示,大量证据支持瑜伽对不孕因素的积极影响。这些包括氧化应激(OS),氧化性DNA损伤(ODD),表观遗传变化,荷尔蒙平衡,卵巢功能,月经不调,和减轻压力。总之,瑜伽成为不孕症的一种有前途的辅助疗法,证明有可能减轻影响生殖成功的关键因素。尽管初步证据表明瑜伽对不孕症的积极影响,进一步的临床研究必须确定具体的益处,相关的分子机制,最优协议,和不孕症治疗计划的长期影响。
Infertility, a widespread medical condition affecting numerous couples globally, persists as a challenge despite advances in assisted reproductive technologies (ARTs), often burdened by financial, physical, and emotional strains. Complementary and alternative approaches, notably yoga, have garnered attention for potentially enhancing fertility outcomes. Studies reveal yoga\'s influence on factors contributing to infertility, including reduced oxidative stress (OS) and oxidative DNA damage (ODD). OS, linked to mutagenic base formation, higher malondialdehyde levels, abnormal methylation, and altered gene expression, can impair sperm genome integrity. Yoga\'s efficacy is evident in lowering OS, positively affecting signal transmission, gene expression, and physiological systems. Furthermore, yoga has a positive impact on addressing the dysregulation of apoptosis, resulting in improved processes such as spermatogenesis, sperm maturation, and motility, while also reducing DNA fragmentation. OS correlates with genome-wide hypomethylation, telomere shortening, and mitochondrial dysfunction, contributing to genome instability. Yoga and meditation significantly reduce OS and ODD, ensuring proper reactive oxygen levels and preserving physiological systems. The review explores potential mechanisms underlying yoga\'s positive impact on infertility, including enhanced blood flow, reduced inflammation, relaxation response, and modulation of the hypothalamic-pituitary-adrenal axis. Furthermore, a comprehensive review of the literature reveals substantial evidence supporting the positive effects of yoga on infertility factors. These include oxidative stress (OS), oxidative DNA damage (ODD), epigenetic changes, hormonal balance, ovarian function, menstrual irregularities, and stress reduction. In summary, yoga emerges as a promising adjunctive therapy for infertility, demonstrating the potential to mitigate key factors influencing reproductive success. Although preliminary evidence indicates the positive effects of yoga on infertility, further clinical research is imperative to define specific benefits, molecular mechanisms associated, optimal protocols, and long-term effects in infertility treatment plans.