背景:本研究的目的是研究诊断为大肠癌卵巢转移(OM-CRC)的患者的临床表现,基于计算机断层扫描(CT)结果的病理特征和发展。
方法:研究是在1月份期间对OM-CRC入院进行的,2000年1月,2020年,同时对患者进行检查和影像学统计。
结果:一组21名女性参与者,中位年龄为54岁,年龄从48岁到68岁,被调查了。在单变量分析中,细胞减灭术(CRS)期间的同步转移和R2切除(肉眼可见的残留病灶)与OM-CRC预后呈负相关.多变量分析结果表明,CRS期间R2切除是总生存率(OS)和无进展生存率(PFS)的唯一独立预测因素。OM-CRC病例经常表现出明确的边界线(90.9%),主要为囊性卵巢肿块(90.9%),异质增强(72.3%),中度增强(63.6%),腹膜植入(81.8%)和无淋巴结肿大(90.9%)。
结论:深入了解OM-CRC的病理特征和发展非常重要,为了了解它的诊断,开发有用的治疗干预措施,并预测准确的预后。然而,OM-CRC是一种罕见的恶性卵巢肿瘤,良好的预后需要CRS没有肉眼可见的残留病变。作为我们研究的重要发现。
BACKGROUND: The aim of this study was to study patients diagnosed with ovary metastasis from colorectal carcinoma (OM-CRC) regarding their clinical manifestations, pathological characteristics and developments based on the results of computed tomography (CT).
METHODS: Research was conducted with OM-CRC admissions to our facility during the period of January, 2000 to January, 2020, with examinations of both patients and imaging statistics.
RESULTS: A group of 21 female participants with a median age of 54-year-old, ranging from 48 to 68 years old, were investigated. In the univariate analyses, synchronous metastasis and R2 resection (macroscopic residual lesions) during cytoreductive surgery (CRS) were shown to be negatively associated with the OM-CRC prognosis. Results of the multivariate analysis showed that R2 resection during CRS was the only independent predictor of the overall survival (OS) rate as well as the progression-free survival (PFS) rate. OM-CRC cases frequently exhibited a well-defined borderline (90.9%), predominantly cystic ovarian mass (90.9%), heterogeneous enhancement (72.3%), moderate enhancement (63.6%), peritoneal implantation (81.8%) and an absence of lymphadenopathy (90.9%).
CONCLUSIONS: It is important to develop a thorough comprehension of the pathological characteristics as well as developments of OM-CRC, in order to understand its diagnosis, develop useful therapeutic interventions, and predict accurate prognosis. Nevertheless, OM-CRC is an uncommon malignant ovarian tumor and a good prognosis requires a CRS without macroscopic residual lesions, as a significant finding of our study.