背景:尽管长期暴露于空气污染物与精神障碍有关,现有的研究仍然有限和不一致。我们调查了暴露于颗粒物(PM)和抑郁症状之间的关系,以及睡眠持续时间和身体活动的潜在作用。
方法:使用312,390名10-25岁学生的常见疾病和危险因素监测数据(2019年至2022年),逻辑回归,采用广义线性模型(GLM)和有限三次样条(RCS)研究长期暴露于PM与抑郁症状之间的关系。
结果:发现PM1之间存在显着关联(OR=1.21,95%CI:1.12-1.32),PM2.5(OR=1.24,95%CI:1.19-1.38),和PM10(OR=1.87,95%CI:1.69-2.07),抑郁症状的风险增加。睡眠时间和身体活动缓解了这些关联。睡眠充足组的PM1,PM2.5和PM10对抑郁症状的比值比(ORs)较低(1.02vs.1.49,1.20vs.1.80,2.15vs.2.23),高水平MVPA组较低(1.13vs.1.48,1.14vs.1.58,1.85vs.2.38),在户外活动水平较高的组中较低(1.19vs.1.55,1.23vs.1.63,1.83vs.2.72).
结论:由于横截面设计,关于因果关系的结论仍然是推测性的。
结论:充足的睡眠时间和户外活动可以缓解发展中国家成年人长期暴露于PM引起的心理健康下降。这一贡献增强了我们对将空气污染与心理健康联系起来的机制的理解。
BACKGROUND: Although long-term exposures to air pollutants have been linked to mental disorders, existing studies remain limited and inconsistent. We investigated the relationship between exposure to particulate matter (PM) and depressive symptoms, as well as the potential role of sleep duration and physical activity.
METHODS: Using the surveillance data (2019 to 2022) of common diseases and risk factors among 312,390 students aged 10-25 years, logistic regression, generalized liner model (GLM) and restricted cubic spline (RCS) were employed to investigate the relationship between long-term exposure to PM and depressive symptoms.
RESULTS: Significant associations were found between PM1 (OR = 1.21, 95 % CI: 1.12-1.32), PM2.5 (OR = 1.24, 95 % CI: 1.19-1.38), and PM10 (OR = 1.87, 95 % CI: 1.69-2.07) and increased risks of depressive symptoms. Sleep duration and physical activity relieved these associations. The odds ratios (ORs) of PM1, PM2.5, and PM10 on depressive symptoms were lower in group with sufficient sleep (1.02 vs. 1.49, 1.20 vs. 1.80, 2.15 vs. 2.23), lower in group with high level MVPA (1.13 vs. 1.48, 1.14 vs. 1.58, 1.85 vs. 2.38), and lower in group with high level outdoor activity (1.19 vs. 1.55, 1.23 vs. 1.63, 1.83 vs. 2.72).
CONCLUSIONS: Conclusions about causality remain speculative because of the cross-sectional design.
CONCLUSIONS: Sufficient sleep duration and outdoor activity may mitigate the decline in mental health among adults in developing countries caused by long-term exposure to PM. This contribution enhanced our understanding of the mechanisms linking air pollution to mental health.