orthopaedic research

骨科研究
  • 文章类型: Case Reports
    Segond骨折是一种特殊类型的撕脱性骨折,涉及胫骨平台附近的胫骨近端外侧。Segond骨折表明膝关节韧带损伤。在这个案例报告中,一名29岁的男性分娩司机在低速失去对摩托车的控制后出现急性右膝疼痛。检查发现明显的积液和内侧和外侧关节线压痛。膝盖的前后X光片显示Segond骨折。随后的MRI证实全厚度前交叉韧带(ACL)破裂和内侧副韧带(MCL)撕裂。尽管有手术重建的选择,患者选择保守治疗。在八周的随访中,他表现出令人满意的进步。此病例强调了Segond骨折在没有MRI检查的情况下识别膝关节韧带损伤的诊断意义。它还强调了在某些情况下实行非经营性管理的可行性。
    A Segond fracture is a specific type of avulsion fracture involving the lateral aspect of the proximal tibia adjacent to the tibial plateau. Segond fractures are indicative of ligamentous injury in the knee. In this case report, a 29-year-old male delivery driver presented to the ED with acute onset right knee pain after losing control of his motorbike at low speed. Examination revealed significant effusion and medial and lateral joint line tenderness. An anterior-posterior radiograph of the knee showed a Segond fracture. Subsequent MRI confirmed a full-thickness anterior cruciate ligament (ACL) rupture and medial collateral ligament (MCL) tear. Despite surgical reconstruction options, the patient chose conservative management. At eight-week follow-up, he demonstrated satisfactory progress. This case highlights the diagnostic significance of Segond fractures in identifying ligamentous damage in the knee without the availability of MRI. It also highlights the feasibility of non-operative management in some instances.
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  • 文章类型: Journal Article
    本系统综述,在Prospero注册,旨在确定半月板修复研究的最佳动物模型,从体外实验转向体内研究。数据源包括PubMed、Medline,所有循证医学评论,WebofScience,和Embase在2023年3月进行了搜索。使用系统评价和荟萃分析(PRISMA)指南的首选报告项目筛选研究。提取的数据包括动物模型,实验类型,撕裂类型,外科技术,和衡量的结果,被记录下来,reviewed,并由四位独立审稿人分析。SYstematic实验动物实验审查中心(SYRCLE)Rob工具用于关键评估和偏倚风险评估。在11,719项研究中,包括72份手稿进行数据提取和分析;41份离体关节外研究,20离体关节内研究,只有11项体内研究。采用了六种动物模型:猪,牛,lapine,caprine,犬,还有羊.纵向病变是研究最频繁的撕裂模式,缝合是最常见的修复技术。研究结果主要集中在生物力学评估和粗略观察上。本系统综述可以指导研究者选择半月板修复研究的动物模型,caprine,和离体尸体研究的牛模型,而猪和山羊模型由于与人体解剖学相似而更适合体内研究。在启动方案以改善该领域的标准化之前,研究团队应熟悉各种动物模型的优缺点。
    This systematic review, registered with Prospero, aims to identify an optimal animal model for meniscus repair research, moving from ex vivo experimentation to in vivo studies. Data sources included PubMed, Medline, all Evidence-Based Medicine Reviews, Web of Science, and Embase searched in March 2023. Studies were screened using Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Extracted data including animal model, type of experiment, type of tear, surgical techniques, and measured outcomes, were recorded, reviewed, and analyzed by four independent reviewers. The SYstematic Review Centre for Laboratory animal Experimentation (SYRCLE) Rob tool was used for critical appraisal and risk of bias assessment. Out of 11,719 studies, 72 manuscripts were included for data extraction and analysis; 41 ex vivo extra-articular studies, 20 ex vivo intra-articular studies, and only 11 in vivo studies. Six animal models were employed: porcine, bovine, lapine, caprine, canine, and ovine. Longitudinal lesions were the most frequently studied tear pattern and sutures the most common repair technique. Studied outcomes focused mainly on biomechanical assessments and gross observations. This systematic review can guide researchers in their choice of animal model for meniscus repair research; it highlighted the strengths of the porcine, caprine, and bovine models for ex vivo cadaveric studies, while the porcine and caprine models were found to be more suited to in vivo studies due to their similarities with human anatomy. Research teams should familiarize themselves with the advantages and disadvantages of various animal models before initiating protocols to improve standardization in the field.
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  • 文章类型: Journal Article
    引言在所有医学和外科专业中,研究小组和财团的创建变得越来越普遍。这项调查的目的是评估和描述骨科手术中的合作研究小组和联盟。此外,我们旨在定义研究联盟成员的人口统计数据,特别关注女性和少数群体成员。方法选择以肌肉骨骼/骨科为重点的期刊和一些医学期刊,以确定研究小组和财团发表的文章。2020年至2022年发表的文章进行了手动审查。书目信息,记录作者信息和证据水平(LOE)。对于已确定的财团成员,性别和种族以二元方式定义。结果共确定了92个科研联合体。确定了77组(83.7%)的成员名单,共有2260名研究人员。由于所包括的出版物中缺乏信息,无法确定其余的小组成员,研究小组网站或与相应作者沟通后的相应文章。大多数研究人员是男性(n=1,748,77.3%)和白人(n=1,694,75%)。整形外科医生包括1,613(71.4%)确定的研究人员。骨科医生最常见的研究金培训是儿科(n=370,16.4%),创伤(n=266,11.8%)和运动医学(n=229,10.1%)。该联盟发表了261篇文章:23%的女性是主要(第一)作者,11.1%的女性是高级(最后)作者。非白人研究人员是24.5%的主要作者(n=64)和17.2%的资深作者(n=45)。最常见的证据水平是3级,占所有出版物的45.6%(n=119)。一级证据占已发表文章的12.6%(n=33)。讨论妇女在骨科研究协会中的代表性超过了她们在几乎每个骨科专业协会中的代表性。比较代表性不足的少数群体(URM)在研究联盟中的参与与一般实践的公开数据较少。进一步的调查应分析在骨科手术研究中可以改善性别和种族差异的可能途径。
    Introduction The creation of research groups and consortiums has become more common in all medical and surgical specialities. The purpose of this investigation was to assess and describe collaborative research groups and consortiums within orthopaedic surgery. In addition, we aimed to define the demographics of the research consortium members with particular attention to female and minority members. Methods  Journals with a musculoskeletal/orthopaedic focus and a few medical journals were selected to identify articles published by research groups and consortiums. Articles published from 2020 to 2022 were manually reviewed. Bibliographic information, author information and level of evidence (LOE) were recorded. For identified consortium members, sex and race were defined in a binary manner. Results A total of 92 research consortiums were identified. A list of members was identified for 77 groups (83.7%), totalling 2,260 researchers. The remaining group members were not able to be identified due to the lack of information in the included publications, research group websites or after communicating with the corresponding author for respective articles. Most researchers were male (n=1,748, 77.3%) and white (n=1,694, 75%). Orthopaedic surgeons comprised 1,613 (71.4%) identified researchers. The most common fellowship training for orthopaedic surgeons was paediatrics (n=370, 16.4%), trauma (n=266, 11.8%) and sports medicine (n=229, 10.1%). The consortiums published 261 articles: women were lead (first) authors in 23% and senior (last) authors in 11.1%. Non-white researchers were lead authors in 24.5% (n=64) and senior authors in 17.2% (n=45). The most common level of evidence was level 3, accounting for 45.6% (n=119) of all publications. Level 1 evidence accounted for 12.6% (n=33) of published articles. Discussion Representation of women in orthopaedic research consortiums exceeds their representation in almost every orthopaedic professional society. There is less publicly available data to compare the involvement of under-represented minorities (URMs) in research consortiums to general practice. Further investigations should analyse possible avenues in which gender and racial disparity could be improved within orthopaedic surgery research.
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  • 文章类型: Journal Article
    背景#OrthoTwitter已经发展到传播调查结果并吸引公众。然而,在骨科手术中使用Twitter的学术影响尚不清楚.问题/目的研究的目的是评估作者与手稿Twitter活动和引用之间的关系。方法对2018年17种骨科期刊的稿件进行鉴定。引文,网上提到,影响因素,并获得了亚专业。作者的H-index和Twitter帐户详细信息是针对手稿的子集获得的。评估了Twitter活动与引用之间的关系。结果在Twitter上提到了2,473/4,224(58.5%)手稿(n=29,958次提及),Twitter手稿被引用的频率更高(中位数为10vs.7,p<0.0001)。Twitter提到,影响因素,非开放访问状态,亚专业与引文计数有关。在10、100和1,000Tweet中提到的文章被观察到有1.1倍,1.7倍,引文增加245倍。在作者层面的分析中,156名(20.0%)和216名(27.7%)资深作者拥有Twitter帐户。引文计数与高级作者H指数的增加相关(βest=0.13,p<0.05),Twitter提到(βest=0.0043,p<0.0001),影响因子(βest=0.13,p<0.0001),在Twitter上有第一作者(βest=0.20,p<0.05)或资深作者(βest=0.17,p<0.05)。在关节成形术中发表的文章(βest=0.49,p<0.05),一般利息(βest=0.55,p<0.01),运动(βest=0.63,p<0.01),非开放获取期刊(βest=0.41,p<0.001)被引用更多。H指数与第一作者(rho=0.31,p<0.0001)和高级作者(rho=0.44,p<0.0001)的追随者相关。结论作者Twitter利用与稿件引用独立相关。作者应该意识到社交媒体利用与传统学术影响之间的潜在关联。了解社交媒体利用与学术影响之间的关系对于有效传播研究是必要的。
    Background #OrthoTwitter has evolved to disseminate findings and engage the public. However, the academic impact of Twitter utilization in orthopaedic surgery is unknown. Questions/purposes The purpose of the study was to evaluate relationships between the author and manuscript Twitter activity and citations. Methods Manuscripts in 17 orthopaedic journals from 2018 were identified. Citations, online mentions, impact factors, and subspecialties were obtained. H-index and Twitter account details for authors were obtained for a subset of manuscripts. Relationships between Twitter activity and citations were evaluated. Results 2,473/4,224 (58.5%) manuscripts were mentioned on Twitter (n=29,958 mentions), with Twitter manuscripts cited more frequently (median 10 vs. 7, p<0.0001). Twitter mentions, impact factors, non-open-access status, and subspecialties were associated with citation counts. Articles mentioned in 10, 100, and 1,000 Tweets were observed to have a 1.1-fold, 1.7-fold, and 245-fold increase in citations. In author-level analyses, 156 (20.0%) first and 216 (27.7%) senior authors had Twitter accounts. Citation count was associated with increasing senior author H-index (β est=0.13, p<0.05), Twitter mentions (β est=0.0043, p<0.0001), impact factors (β est=0.13, p<0.0001), and having a first (β est=0.20, p<0.05) or senior author (β est=0.17, p<0.05) on Twitter. Articles published in arthroplasty (β est=0.49, p<0.05), general interest (β est=0.55, p<0.01), sports (β est=0.63, p<0.01), and non-open access journals (β est=0.41, p<0.001) were cited more. H-index correlated with followers for first (rho=0.31, p<0.0001) and senior authors (rho=0.44, p<0.0001). Conclusion Author Twitter utilization is independently associated with manuscript citations. Authors should be aware of the potential association between social media utilization and traditional academic impact. Understanding the relationship between social media utilization and academic impact is necessary to effectively disseminate research.
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  • 文章类型: Journal Article
    经济评价为评估替代方案或干预措施的成本和后果提供了一个框架。医疗保健环境下经济评估的一种常见工具是决策分析模型,它合成参数输入的信息(例如,临床事件或健康状况的概率或成本)来自多个来源,需要应用数学技术,通常在软件程序中。近年来,已经发表了大量基于决策分析模型的骨科干预措施经济评估。本注释概述了一些可以帮助读者的问题,审稿人,和决策者从基于决策分析模型的骨科干预措施的经济评估中解释证据。引用本文:骨关节J2023;105-B(1):17-20。
    Economic evaluation provides a framework for assessing the costs and consequences of alternative programmes or interventions. One common vehicle for economic evaluations in the healthcare context is the decision-analytic model, which synthesizes information on parameter inputs (for example, probabilities or costs of clinical events or health states) from multiple sources and requires application of mathematical techniques, usually within a software program. A plethora of decision-analytic modelling-based economic evaluations of orthopaedic interventions have been published in recent years. This annotation outlines a number of issues that can help readers, reviewers, and decision-makers interpret evidence from decision-analytic modelling-based economic evaluations of orthopaedic interventions.Cite this article: Bone Joint J 2023;105-B(1):17-20.
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  • 文章类型: Journal Article
    目的:小儿髁上肘关节移位骨折的治疗仍存在广泛争议,实际操作尚不清楚。这项全国性的培训人员合作旨在评估英国各地这些损伤的手术和术后管理。
    方法:本研究由西南骨科研究部(SWORD)领导,由SupraMan协作组进行。回顾性识别2019年1月1日至2019年12月31日期间接受手术的移位小儿髁上肘关节骨折,并通过研究电子数据捕获(REDCap)收集其匿名数据。
    结果:在41家医院中确定了972名患者。受伤的平均年龄为6.3岁(1至15岁),504人为男性(52%),583涉及左侧(60%),538例Gartland3型骨折(55%)。从受伤到剧院的中位时间为16小时(四分位间距(IQR)6.6至22),300名患者(31%)在受伤当天接受了手术,91人(9%)在晚上10:00至上午8:00接受了手术。总的来说,910例患者(94%)进行了克氏针(K)线)固定,其中869例(95%)进行了经皮固定,62例患者(6%)在麻醉(MUA)和铸造下进行了操作。544例(59.5%)采用交叉克氏针结构固定。总的来说,由儿科骨科顾问进行或监督的208例固定病例(61%)进行了侧方固定,而由非儿科骨科顾问执行或监督的153例(27%)固定病例使用了仅侧方固定。总的来说,在手术室中移除129根经皮导线(16%)。在儿科骨科顾问进行或监督的341例经皮金属丝固定中,11人(3%)在剧院接受了电线移除,而在非儿科骨科顾问进行或监督下的528例经皮钢丝固定病例中,有118例(22%)在手术室进行了钢丝摘除。四名MUA患者(6%)和七名K线固定患者(0.8%)在30天内需要进行翻修手术以进行移位。
    结论:英国儿童髁上肘关节骨折的治疗方法各不相同。涉及儿科骨科顾问的患者病例,仅在临床上进行横向K线固定和去除线的趋势增加。在所有固定配置中都确定了需要翻修手术的低移位率。引用本文:骨关节J2023;105-B(1):82-87。
    Management of displaced paediatric supracondylar elbow fractures remains widely debated and actual practice is unclear. This national trainee collaboration aimed to evaluate surgical and postoperative management of these injuries across the UK.
    This study was led by the South West Orthopaedic Research Division (SWORD) and performed by the Supra Man Collaborative. Displaced paediatric supracondylar elbow fractures undergoing surgery between 1 January 2019 and 31 December 2019 were retrospectively identified and their anonymized data were collected via Research Electronic Data Capture (REDCap).
    A total of 972 patients were identified across 41 hospitals. Mean age at injury was 6.3 years (1 to 15), 504 were male (52%), 583 involved the left side (60%), and 538 were Gartland type 3 fractures (55%). Median time from injury to theatre was 16 hours (interquartile range (IQR) 6.6 to 22), 300 patients (31%) underwent surgery on the day of injury, and 91 (9%) underwent surgery between 10:00 pm and 8:00 am. Overall, 910 patients (94%) had Kirschner (K)-wire) fixation and these were left percutaneous in 869 (95%), while 62 patients (6%) had manipulation under anaesthetic (MUA) and casting. Crossed K-wire configuration was used as fixation in 544 cases (59.5%). Overall, 208 of the fixation cases (61%) performed or supervised by a paediatric orthopaedic consultant underwent lateral-only fixation, whereas 153 (27%) of the fixation cases performed or supervised by a non-paediatric orthopaedic consultant used lateral-only fixation. In total, 129 percutaneous wires (16%) were removed in theatre. Of the 341 percutaneous wire fixations performed or supervised by a paediatric orthopaedic consultant, 11 (3%) underwent wire removal in theatre, whereas 118 (22%) of the 528 percutaneous wire fixation cases performed or supervised by a non-paediatric orthopaedic consultant underwent wire removal in theatre. Four MUA patients (6%) and seven K-wire fixation patients (0.8%) required revision surgery within 30 days for displacement.
    The treatment of supracondylar elbow fractures in children varies across the UK. Patient cases where a paediatric orthopaedic consultant was involved had an increased tendency for lateral only K-wire fixation and for wire removal in clinic. Low rates of displacement requiring revision surgery were identified in all fixation configurations.Cite this article: Bone Joint J 2023;105-B(1):82-87.
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  • 文章类型: Journal Article
    股骨颈(NOF)骨折患者30天死亡率显著。在英国2019年冠状病毒病(COVID-19)大流行期间,NOF骨折的发病率仍然很高。因此,许多病例并发严重急性呼吸综合征冠状病毒2感染。我们对来自英国的所有与大流行期间NOF骨折和30天死亡率结局相关的研究进行了系统评价和荟萃分析。根据系统评价和荟萃分析指南的首选报告项目进行系统评价和荟萃分析并报告。两名审稿人在Medline上独立搜索了2020年3月1日至2020年11月1日在英国发表的研究。比较了以下结果:30天死亡率,手术时间到了,和麻醉风险。本综述共包括五篇文章。总的来说,286例NOF骨折和COVID-19感染患者,30天死亡率为30.5%至50%(比值比=6.02;95%置信区间=4.10-8.85;χ2=4.82;I2=58%)。在一些研究中,大多数患者也注意到,由于COVID-19相关的延误,手术时间增加。死亡率评分(Charlson合并症指数,诺丁汉髋部骨折评分)未能准确预测死亡风险。与COVID-19阴性组相比,NOF骨折患者同时感染COVID-19使30天死亡率增加6倍。应努力优化手术时间,并考虑较高依赖单位的术后护理。未来死亡率预测评分的更新应包括COVID-19感染作为一个重要因素。
    Neck of femur (NOF) fracture patients have significant 30-day mortality. The incidence of NOF fractures remained high during the coronavirus disease 2019 (COVID-19) pandemic in the United Kingdom. Consequently, numerous cases were complicated with concurrent severe acute respiratory syndrome coronavirus 2 infection. We performed a systematic review and meta-analysis of all studies from the United Kingdom related to NOF fractures and 30-day mortality outcomes during the pandemic.   A systematic review and meta-analysis was performed and reported as per the Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines. Two reviewers independently searched on Medline for studies that were published between the 1st of March 2020 and the 1st of November 2020 in the United Kingdom. The following outcomes were compared: 30-day mortality, time to surgery, and anaesthetic risk.   A total of five articles were included in this review. In total, 286 patients with NOF fractures and COVID-19 infection were identified, with 30-day mortality ranging from 30.5% to 50% (odds ratio = 6.02; 95% confidence interval = 4.10-8.85; χ2 = 4.82; I2 = 58%). Increased time to surgery due to COVID-19-related delays was also noted for the majority of patients in some studies. Mortality scores (Charlson Comorbidity Index, Nottingham Hip Fracture Score) failed to accurately predict the mortality risk. Concurrent infection of COVID-19 in patients with NOF fractures increases the 30-day mortality sixfold compared to the COVID-19-negative group. Efforts should be made to optimise time to surgery as well as consideration of postoperative care in higher dependency units. Future updates in mortality predicting scores should include COVID-19 infection as a significant factor.
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  • 文章类型: Journal Article
    Background The number of publications is widely used as a measure of academic productivity in the field of orthopaedics. How \"productive\" a physician is has a great influence on consideration for employment, compensation, and promotions. Predictors of potential high-output researchers would be of value to the orthopaedic department and university leadership for new faculty evaluation. Methods The study population included orthopaedic faculty from the top 10 orthopaedic institutions in the United States. Their names and the number of publications at each point in their training (medical school, residency, and fellowship) and early career (first five and 10 years following fellowship) along with a total number of publications to date were collected by using PubMed. Results Strong correlations were seen between publications during total training and publications output in the first five years following fellowship (rs =0.717, P<0.0001). However, no significant correlations were found comparing publications during each stage of training and the first 10 years following fellowship. A moderate positive correlation was found when comparing publications during medical school and residency output (rs =0.401, P<0.0001). Conclusions The data presented here may be utilized by department chairs during the evaluation of faculty and candidates to not interpret the number of publications during training and early career as a gauge of research interest and potential for future publications. Program directors may also use the only moderate correlation between publications in medical school and residency when evaluating applications as support of a more holistic review of applicants to determine research interest.
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