检查女性对运动的食欲调节反应的有限工作集中在月经周期的卵泡期(FP)。这是一个重要的限制,因为雌二醇(E2)和孕酮(P4)在黄体期(LP)中浓度更高,会在各个阶段波动。
目的:研究FP和LP对高强度连续运动(VICT)的食欲调节反应。
方法:在FP和LP中,12名女性在80%V•O2max下完成了30分钟的VICT。E2,P4,酰化生长素释放肽,活性肽酪氨酸-酪氨酸(PYY),活性胰高血糖素样肽-1(GLP-1),和食欲感知是在运动前测量的,0-,30-,运动后90分钟。记录2天的能量摄入(每个疗程的前一天和前一天)。使用一系列双向重复测量ANOVA来比较所有因变量。
结果:运动前E2(P=0.005,d=1.00)和P4(P<0.001,d=1.41)浓度在LP中高于FP,运动后0和30分钟均增加(E2:P<0.009;P4:P<0.001,d=0.63)。运动前,运动后0分钟(P=0.006,d=0.97)和90分钟(P=0.029,d=0.72)时,FP与LP中的酰化生长素释放肽较低。经期对PYY无差异(P=0.359,ηp2=0.092),GLP-1(P=0.226,ηp2=0.130),或总体食欲(P=0.514,ηp2=0.066)。与FP相比,LP当天的能量摄入量更高(P=0.003,d=1.2)。
结论:与LP相比,FP中的酰化生长素释放肽较低,尽管厌食激素或主观食欲没有差异,LP治疗当天的能量摄入较高,提示整个月经周期存在重要差异,LP中卵巢激素浓度较高可能会影响运动反应.
Limited work examining woman\'s appetite-regulatory response to exercise has been focused on the follicular phase (FP) of the menstrual cycle. This is an important limitation as estradiol (E2) and progesterone (P4) fluctuate across phases with greater concentrations in the luteal phase (LP).
OBJECTIVE: To examine the appetite-regulatory response to vigorous-intensity continuous exercise (VICT) in the FP and LP.
METHODS: Twelve women completed 30 min of VICT at 80% V˙O2max in the FP and LP. E2, P4, acylated ghrelin, active peptide tyrosine-tyrosine (PYY), active glucagon-like peptide-1 (GLP-1), and appetite perceptions were measured pre-exercise, 0-, 30-, and 90-min post-exercise. Energy intake was recorded for a 2-day period (day before and of each session). A series of two-way repeated measure ANOVA were used to compare all dependent variables.
RESULTS: Pre-exercise E2 (P = 0.005, d = 1.00) and P4 (P < 0.001, d = 1.41) concentrations were greater in the LP than the FP and exercise increased both at 0- and 30-min post-exercise (E2: P < 0.009; P4: P < 0.001, d = 0.63). Acylated ghrelin was lower in the FP versus LP at pre-exercise as well as 0-min (P = 0.006, d = 0.97) and 90-min (P = 0.029, d = 0.72) post-exercise. There were no differences of menstrual phase on PYY (P = 0.359, ηp2 = 0.092), GLP-1 (P = 0.226, ηp2 = 0.130), or overall appetite (P = 0.514, ηp2 = 0.066). Energy intake was greater on the day of in the LP versus the FP (P = 0.003, d = 1.2).
CONCLUSIONS: Acylated ghrelin was lower in the FP compared to the LP and though there were no differences in anorexigenic hormones or subjective appetite, energy intake was greater on the day of the session in the LP suggesting important differences across the menstrual cycle where greater concentrations of ovarian hormones in the LP may blunt the exercise response.