一个斯派,8岁雌性贵宾犬,体重5.7公斤,主诉是视力障碍。视力评估,包括瞳孔光反射,威胁回应,炫目反射,在明视和暗视环境中进行迷宫导航,除了右眼的直接瞳孔光反射阳性和从右眼到左眼的合意瞳孔光反射阳性外,双眼均显示出阴性反应。系统评价,包括神经状态,血液剖面,和胸部X光片,没有发现任何异常。完成眼科检查,眼超声检查,视网膜电图没有确定失明的原因。在Funduscopy之后,左眼表现出增加的视盘直径,模糊的视盘边界,和生理坑的损失,以及血管弯曲的增加。在右眼,在非绒面眼底有多焦点褪色区域,在绒面眼底有一些色素斑点被暗淡的绒面反射区域包围。光学相干断层扫描显示左眼乳头周围区域的视神经头和布鲁赫膜严重的前变形。磁共振成像显示不规则,宽基鞍上肿块,具有颅内高压的特征,包括第三脑室的背侧位移,大脑镰向右移动,经天幕疝,周围水肿,后巩膜变平/突出,左侧视神经鞘直径大于右侧。这是第一份全面的报告,描述了患有脑肿瘤的狗的单侧乳头水肿,使用先进的眼科和神经成像模式。
A spayed, 8-year-old female Poodle, weighing 5.7 kg, was presented with the chief complaint of vision impairment. Vision assessment, including pupillary light reflexes, menace response, dazzle reflex, and maze navigation in photopic and scotopic circumstances, revealed a negative response in both eyes except for positive direct pupillary light reflex in the right eye and positive consensual pupillary light reflex from the right eye to the left eye. Systemic evaluation, including neurologic status, blood profile, and thoracic radiographs, did not reveal any abnormalities. Complete ophthalmic examinations, ocular ultrasonography, and electroretinography did not identify a cause of blindness. Upon funduscopy, the left eye exhibited an increased optic disk diameter, blurred optic disk borders, and loss of the physiologic pit, as well as an increase in vascular tortuosity. In the right eye, there were multifocal depigmented areas in the non-tapetal fundus and several pigmented spots surrounded by a region of dull tapetal reflection in the tapetal fundus. The optical coherence tomography revealed severe anterior deformation of the optic nerve head and Bruch\'s membrane in the peripapillary region of the left eye. Magnetic resonance imaging revealed an irregular, broad-based suprasellar mass, with features suggestive of intracranial hypertension, including dorsal displacement of third ventricles, a rightward shift of the falx cerebri, trans-tentorial herniation, perilesional edema, flattening/protrusion of the posterior sclera, and lager optic nerve sheath diameter in left side than right side. This is the first comprehensive report that describes unilateral papilledema in a dog with a brain tumor, using advanced ophthalmic and neuro-imaging modalities.