目的:本研究的目的是描述和比较基线人口统计学,眼,以及视盘凹陷(ODP)或视盘缺损(ODC)黄斑病变患者队列的影像学特征。
方法:本回顾性研究纳入了2017年6月至2022年12月临床检查诊断为ODP或ODC的患者。这些患者的基线人口统计学,眼部特征,并对光学相干断层扫描(OCT)成像特征进行分析。
结果:眼底检查发现11例ODP患者11只眼,9例ODC患者14只眼,分别。在OCT上,ODP(n=10)的黄斑病变发生率高于ODC(n=4)[p=0.004]例。ODP的眼睛更可能表现出视网膜裂开和/或浆液性黄斑脱离[SMD](n=7,70%),视网膜裂孔与视盘的通信(p=0.015),而SMD不与视神经盘通信(p=0.005),和显著的视网膜外层变薄(p=0.015)。相比之下,患有ODC的眼睛仅表现出SMD(p=0.005),并且在非结肠样视网膜上没有视网膜裂开。ODC中的SMD与视盘的边缘连通。在这两个临床实体中,在SMD中观察到超反射焦点。
结论:总之,OCT基线黄斑病变特征,包括它的类型,location,以及与视盘的关系,是ODP和ODC之间最显着的特征之一。
背景:不适用。
OBJECTIVE: The aim of this study is to describe and compare the baseline demographic, ocular, and imaging characteristics of a cohort of patients with optic disc pit (ODP) or optic disc coloboma (ODC) maculopathy.
METHODS: This retrospective study included patients diagnosed with ODP or ODC on clinical examination between June 2017 and December 2022. These patients\' baseline demographics, ocular characteristics, and optical coherence tomography (OCT) imaging characteristics were analyzed.
RESULTS: Fundus examination revealed 11 eyes of 11 patients with ODP and 14 eyes of 9 patients with ODC, respectively. On OCT, maculopathy was observed more frequently in ODP (n = 10) than in ODC (n = 4) [p = 0.004] cases. Eyes with ODP were more likely to exhibit retinoschisis and/or serous macular detachment [SMD] (n = 7, 70%), communication of the retinoschisis with the optic disc (p = 0.015), whereas the SMD did not communicate with the optic disc (p = 0.005), and significant outer retinal layer thinning (p = 0.015). In contrast, eyes with ODC exhibited only SMD (p = 0.005) and no retinoschisis on the non-colobomatous retina. SMD in ODC communicated with the margin of the optic disc. In both clinical entities, hyperreflective foci were observed in the SMD.
CONCLUSIONS: In summary, baseline maculopathy characteristics on OCT, including its type, location, and relationship to the optic disc, are among the most distinguishing characteristics between an ODP and an ODC.
BACKGROUND: Not applicable.