目的：研究眼用粘弹性装置（OVD）和不同手术入路对环形撕囊（CCC）制作前后眼内压（IOP）的影响，以此作为前房稳定性的衡量标准。
方法：对去核猪眼睛进行前瞻性实验WetLab研究。眼压在CCC前后用iCare回弹眼压计测量(iCareic200；iCare芬兰Oy，万塔,芬兰)。使用的OVD是粘性的[Z-Hyalin，CarlZeissMeditecAG,德国；透明质酸(HA)]和分散的[Z-Celcoat，CarlZeissMeditecAG,德国；羟丙基甲基纤维素病(HPMC)]。CCC是使用尿钳或23g微镊子与OVD的不同组合创建的。
结果：使用尿钳，CCC期间眼压从63.65±6.44降至11.25±3.63mmHg。使用不同的OVD没有区别。使用23g微镊子，眼压从65.35±8.15降至36.55±6.09mmHg。无论使用何种OVD，使用尿钳或23g微钳的眼压下降之间的差异都非常显着。
结论：与摘除猪眼睛的主要切口相比，使用侧孔进行撕囊手术可降低眼压。分歧OVD的运用对IOP下降没有显著影响。
OBJECTIVE: To investigate the influence of ophthalmic viscoelastic devices (OVDs) and different surgical approaches on the intraocular pressure (IOP) before and after creation of the curvilinear circular capsulorhexis (CCC) as a measure for anterior chamber stability during this maneuver.
METHODS: Prospective experimental WetLab study carried out on enucleated porcine eyes. IOP was measured before and after CCC with the iCare Rebound tonometer (iCare ic200; iCare Finland Oy, Vantaa, Finland). The OVDs used were a cohesive one [Z-Hyalin, Carl Zeiss Meditec AG, Germany; hyaluronic acid (HA)] and a dispersive [Z-Celcoat, Carl Zeiss Meditec AG, Germany; hydroxy propylmethylcellulosis (HPMC)]. The CCC was created using Utrata forceps or 23 g microforceps in different combinations with the OVDs.
RESULTS: Using the Utrata forceps the IOP dropped from 63.65±6.44 to 11.25±3.63 mm Hg during the CCC. The use of different OVDs made no difference. Using the 23 g microforceps the IOP dropped from 65.35±8.15 to 36.55±6.09 mm Hg. The difference between IOP drop using either Utrata forceps or 23 g microforceps was highly significant regardless of the OVD used.
CONCLUSIONS: Using the sideport for the creation of the capsulorhexis leads to a lesser drop in IOP during this maneuver compared to the main incision in enucleated porcine eyes. The use of different OVD has no significant influence on IOP drop.
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