背景:术中神经生理监测(IOM)在提高神经外科手术期间患者的安全性方面起着关键作用。这项至关重要的技术涉及对诱发电位的连续测量,以提供早期警报并确保保留关键的神经结构。主要挑战之一是有效记录具有语义丰富特征的IOM活动。本研究旨在通过开发基于本体的工具来解决这一挑战。
方法:我们将IOM文档本体(IOMDO)和相关工具的开发分为三个不同的阶段。初始阶段侧重于本体的创建,借鉴OBO(开放生物和生物医学本体论)原理。随后的阶段涉及敏捷软件开发,一种灵活的方法来封装不同的需求并迅速生成原型。最后一个阶段需要在现实世界的文档设置中进行实际评估。这个关键阶段使我们能够收集第一手的见解,评估工具的功能和功效。在此阶段进行的观察形成了必要调整的基础,以确保工具的生产利用。
结果:本体论的核心实体围绕IOM的中心方面,包括以时间戳为特征的测量,type,值,和位置。几个本体论的概念和术语被整合到IOMDO中,例如,解剖学基础模型(FMA),与一般外科术语相关的人类表型本体论(HPO)和外科手术过程模型本体论(OntoSPM)。为扩展本体和相关知识库而开发的软件工具是使用JavaFX构建的,用于用户友好的前端,使用ApacheJena构建的,用于强大的后端。该工具的评估涉及测试用户,他们一致发现界面可访问和可用,即使是那些没有广泛技术专长的人。
结论:通过建立结构化和标准化的框架来表征IOM事件,我们基于本体的工具具有提高文档质量的潜力,通过改善知情决策的基础,使患者护理受益。此外,研究人员可以利用语义丰富的数据来识别趋势,模式,以及加强外科实践的领域。要通过基于本体的方法优化文档,解决与不良事件本体相关的潜在建模问题至关重要。
BACKGROUND: Intraoperative neurophysiological monitoring (IOM) plays a pivotal role in enhancing patient safety during neurosurgical procedures. This vital technique involves the continuous measurement of evoked potentials to provide early warnings and ensure the preservation of critical neural structures. One of the primary challenges has been the effective documentation of IOM events with semantically enriched characterizations. This study aimed to address this challenge by developing an
ontology-based tool.
METHODS: We structured the development of the IOM Documentation Ontology (IOMDO) and the associated tool into three distinct phases. The initial phase focused on the ontology\'s creation, drawing from the OBO (Open Biological and Biomedical
Ontology) principles. The subsequent phase involved agile software development, a flexible approach to encapsulate the diverse requirements and swiftly produce a prototype. The last phase entailed practical evaluation within real-world documentation settings. This crucial stage enabled us to gather firsthand insights, assessing the tool\'s functionality and efficacy. The observations made during this phase formed the basis for essential adjustments to ensure the tool\'s productive utilization.
RESULTS: The core entities of the
ontology revolve around central aspects of IOM, including measurements characterized by timestamp, type, values, and location. Concepts and terms of several ontologies were integrated into IOMDO, e.g., the Foundation Model of Anatomy (FMA), the Human Phenotype Ontology (HPO) and the
ontology for surgical process models (OntoSPM) related to general surgical terms. The software tool developed for extending the ontology and the associated knowledge base was built with JavaFX for the user-friendly frontend and Apache Jena for the robust backend. The tool\'s evaluation involved test users who unanimously found the interface accessible and usable, even for those without extensive technical expertise.
CONCLUSIONS: Through the establishment of a structured and standardized framework for characterizing IOM events, our ontology-based tool holds the potential to enhance the quality of documentation, benefiting patient care by improving the foundation for informed decision-making. Furthermore, researchers can leverage the semantically enriched data to identify trends, patterns, and areas for surgical practice enhancement. To optimize documentation through ontology-based approaches, it\'s crucial to address potential modeling issues that are associated with the
Ontology of Adverse Events.