背景:颅底病变的内窥镜检查方法越来越多,以及随后的并发症,尤其是长期而言,也得到了部分澄清。然而,没有关于儿童鼻内镜颅底手术(EESBS)对气味和面部发育以及长期发育的影响的信息。我们进行了这项研究,以调查使用鼻内镜方法接受颅底手术的小儿患者的术后嗅觉功能和面部发育。
方法:我们评估了气味测试,鼻窦症状,长期随访后接受鼻内镜颅底手术的儿童患者的面部发育。使用“Sniffin\'Sticks\”测试套件评估气味,它评估了T(气味阈值),D(气味辨别),和I(气味识别)参数。使用SNOT-22(鼻窦结果测试)问卷评估鼻窦症状。SNA(Sella-nasion-A点),SNB(Sella-nasion-B点),和ANB(A点-nasion-B点)角度通过颌面断层扫描和磁共振成像计算)来评估面部发育。将数据与健康对照组进行比较。
结果:我们纳入了30名患者,其中包括19名(63.3%)男孩和11名(36.7%)女孩,病例组和对照组之间年龄无差异。平均随访期为7年。气味测试数据,头颅测量,和SNOT-22分析结果显示两组间差异无统计学意义。
结论:据我们所知,这是一项综合性研究,在评估EESBS后儿童面部发育方面,随访时间最长,使用Sniffin\'Sticks检测试剂盒分析气味和使用SNOT-22分析生活质量。嗅觉功能,面部发育,儿童EESBS术后长期随访后生活质量未受影响。尽管这种手术方法是微创的,我们建议考虑并发症的可能性,并且该程序应由具有足够设备的经验丰富的手术团队进行。
BACKGROUND: Endoscopic approaches for skull base pathologies are increasingly being performed, and the subsequent complications, especially in the long term, have also been partially clarified. However, there is no information on the effects of endoscopic endonasal skull base surgeries (EESBS) in children on
odor and facial development in parallel with long-term development. We conducted this study to investigate postoperative olfactory function and facial development in pediatric patients who underwent skull base surgery using the endoscopic endonasal method.
METHODS: We evaluated the smell test, sinonasal symptoms, and facial development of pediatric patients who underwent endoscopic endonasal skull base surgery after long-term follow-up.
Odor was evaluated using the \"Sniffin\' Sticks\" test kit, which assessed the T (
odor threshold), D (
odor discrimination), and I (
odor identification) parameters. Sinonasal symptoms were evaluated using the SNOT-22 (sinus-nose outcome test) questionnaire. SNA (sella-nasion-A point), SNB (sella-nasion-B point), and ANB (A point-nasion-B point) angles were calculated from maxillofacial tomography and magnetic resonance imaging) to evaluate facial development. Data were compared with those of the healthy control group.
RESULTS: We included 30 patients comprising 19 (63.3%) boys and 11 (36.7%) girls, with no age difference between case and control groups. The mean follow-up period was 7 years.
Odor test data, cephalometric measurements, and SNOT-22 analysis results showed no statistically significant differences between the two groups.
CONCLUSIONS: To our knowledge, this is a comprehensive study with the longest follow-up period in terms of evaluation of facial development after EESBS in children to analyze
odor using the Sniffin\' Sticks test kit and the quality of life using SNOT-22. Olfactory function, facial development, and quality of life remained unaffected after long-term follow-up after EESBS in children. Although this surgical approach is minimally invasive, we recommend considering the possibility of complications, and the procedure should be performed by an experienced surgical team with adequate equipment.