未经授权:我们描述了由异常Wickerhamomyces引起的术后真菌性眼内炎的病例,一种机会性酵母,在自然界中常见,但在眼部感染中很少作为病原体。这将是第二例报告的W.反常眼内炎。
UNASSIGNED:一名患者因白内障手术中无意的眼穿孔和视网膜脱离而出现致密的玻璃体。在第一次玻璃体视网膜手术后的几天内,发现了慢性术后眼内炎。只有在几次手术以及玻璃体内抗生素和取样后,检测到wickerhomyces。口服伏立康唑和人工晶状体摘除治疗控制了感染。
未经授权:Wickerhamomycesanalomus,尽管在我们的情况下不是特别咄咄逼人,对各种随后的玻璃体视网膜手术有抵抗力。对治疗无反应导致我们思考真菌的病因,幸运的是,培养物对这种酵母呈阳性。结合抗真菌治疗,人工晶状体移植可能在治疗中起着重要作用。
未经证实:真菌性眼内炎病例必须高度怀疑。人工晶状体外植术和口服抗真菌治疗都是治疗W.反常眼内炎的有效选择。
UNASSIGNED: We describe the case of a postoperative fungal endophthalmitis caused by Wickerhamomyces anomalus, an opportunistic yeast common in nature but rare as a causative agent in ocular infections. This would be the second reported case of W. anomalus endophthalmitis.
UNASSIGNED: A patient came to our hospital with a dense hemovitreous caused by an inadvertent ocular perforation and retinal detachment during a cataract surgery. In the days following the first vitreoretinal surgery a chronic postoperative endophthalmitis was evidenced. Only after several surgeries as well as intravitreal antibiotics and sample takings, Wickerhamomyces was detected. The treatment with oral voriconazole and an intraocular lens extraction controlled the infection.
UNASSIGNED: Wickerhamomyces anomalus, despite not being particularly aggressive in our case, was resistant to various consequent vitreoretinal surgeries. The unresponsiveness to treatment led us to contemplate the fungal etiology, and fortunately the cultures were positive for this yeast. In conjunction to antifungal therapy, it is possible that the IOL explantation played an important role in the treatment.
UNASSIGNED: A high index of suspicion must be held in cases of fungal endophthalmitis. Both IOL explantation and oral antifungal therapy are useful treatment options in cases of W. anomalus endophthalmitis.