环磷酰胺,烷化剂,很少被观察到会引起指甲的蓝色变色,通常被低估的事件。我们描述了一名中年男性接受地塞米松-环磷酰胺脉冲治疗天疱疮的情况,指甲呈蓝灰色变色。将这种表现与其他疾病如指甲设备黑色素瘤(NAM)区分开来是至关重要的,这可能会以稍微不同的方式表现出来。我们还报告了在这种情况下观察到的甲镜发现。
Cyclophosphamide, an alkylating agent, has rarely been observed to cause a bluish discoloration of nails, an occurrence that is typically underreported. We describe the case of a middle-aged male undergoing dexamethasone-cyclophosphamide pulse therapy for pemphigus foliaceus, who exhibited bluish-gray discoloration of the nails. It is crucial to differentiate this presentation from other conditions such as nail apparatus melanoma (NAM), which may manifest in a slightly different manner. We also report the onychoscopic findings observed in this case.