目的:本研究的目的是全面检查身体活动不足(PA)和认知活动(CA),和社会活动(SA)和肌少症的发展。
方法:我们进行了两波调查。在第一波调查中,我们针对三个类别-PA中的每一个向参与者提出了五个问题,CA,SA。低活动组被定义为在五个问题中的一个或多个问题中属于下降类别的人。在第1波和第2波中,我们评估了参与者的肌少症状态。欧洲老年人肌肉减少症工作组2的修订定义用于确定肌肉减少症,和亚洲工作组的肌肉减少症标准被用于肌肉质量的截止点,握力,步行速度。
结果:在第二波中,我们能够追踪2,530名参与者(平均年龄75.0±4.7岁,47.8%的男性)。多变量logistic回归显示,低PA参与者面临更高的发生肌少症的风险,多次填补之前和之后(比值比[OR]1.62,95%置信区间(CI)1.22-2.15;填补后OR1.62,95%CI1.21-2.18);低SA组在多次填补之前和之后也显示出较高的肌肉减少症发生率(OR1.31,95%CI1.05-1.64)。
结论:每种低PA和SA都独立地导致生命后期的肌肉减少症。不仅鼓励PA,还有SA,可有效预防老年人的肌肉减少症。
OBJECTIVE: The purpose of the present study was to comprehensively examine the association between inadequate physical activity (PA), cognitive activity (CA), and social activity (SA) and the development of sarcopenia.
METHODS: We conducted a two-wave survey. In the first-wave survey, we asked participants five questions for each of the three categories-PA, CA, and SA. The low-activity group was defined as those who fell into the decline category for one or more of the five questions. In both Wave 1 and Wave 2, we assessed the sarcopenia status of our participants. The revised definition of the European Working Group on Sarcopenia in Older People 2 was used to determine sarcopenia, and the Asian Working Group for Sarcopenia criteria were used for cut-off points for muscle mass, grip strength, and walking speed.
RESULTS: In the second wave, we were able to follow 2,530 participants (mean age 75.0 ± 4.7 years, 47.8% men). A multivariable logistic regression showed that low-PA participants face a higher risk of incident sarcopenia, both before and after multiple imputations (odds ratio [OR] 1.62, 95% confidence interval (CI) 1.22-2.15 before imputation; OR 1.62, 95% CI 1.21-2.18 after imputation); the low-SA group also showed a higher risk of incident sarcopenia both before and after multiple imputations (OR 1.31, 95% CI 1.05-1.64 before imputation; OR 1.33, 95% CI 1.07-1.65 after imputation).
CONCLUSIONS: Each low PA and SA independently led to incident sarcopenia late in life. Encouraging not only PA, but also SA, may be effective to prevent sarcopenia among older adults.