目的:先前的研究表明,听音乐有可能对卒中后认知障碍(PSCI)患者的认知功能和情绪产生积极影响。偏好自我选择的音乐可能会产生更好的结果。然而,没有足够的临床证据表明在常规康复护理中使用音乐聆听治疗PSCI.这项随机对照试验(RCT)旨在研究个性化音乐聆听对情绪改善的影响。日常生活活动(ADL),以及PSCI患者的认知功能。
方法:将34例PSCI患者随机分为音乐组和对照组。音乐组的患者接受了为期三个月的个性化音乐收听干预。干预涉及收听针对每个人的文化量身定制的个性化播放列表,民族,社会背景,生活经历,和个人音乐偏好。相比之下,对照组患者听白噪声作为安慰剂。认知功能,神经功能,心情,和ADLs进行了评估。
结果:治疗三个月后,与对照组相比,音乐组显示出明显更高的蒙特利尔认知评估(MoCA)得分(p=0.027),特别是在延迟召回(p=0.019)和定向(p=0.023)领域。此外,音乐小组在美国国立卫生研究院卒中量表(NIHSS)中表现出明显更好的得分(p=0.008),Barthel指数(BI)(p=0.019),与对照组相比,Zarit照顾者负担访谈(ZBI)(p=0.008)。通过汉密尔顿焦虑量表(HAMA)和汉密尔顿抑郁量表(HAMD)测量,未发现对情绪的影响。
结论:个性化听音乐可促进认知和神经功能的恢复,改进ADL,减少PSCI患者的护理负担。
OBJECTIVE: Previous studies have suggested that music listening has the potential to positively affect cognitive functions and mood in individuals with post-stroke cognitive impairment (PSCI), with a preference for self-selected music likely to yield better outcomes. However, there is insufficient clinical evidence to suggest the use of music listening in routine rehabilitation care to treat PSCI. This randomized control trial (RCT) aims to investigate the effects of personalized music listening on mood improvement, activities of daily living (ADLs), and cognitive functions in individuals with PSCI.
METHODS: A total of 34 patients with PSCI were randomly assigned to either the music group or the control group. Patients in the music group underwent a three-month personalized music-listening intervention. The intervention involved listening to a personalized playlist tailored to each individual\'s cultural, ethnic, and social background, life experiences, and personal music preferences. In contrast, the control group patients listened to white noise as a placebo. Cognitive function, neurological function, mood, and ADLs were assessed.
RESULTS: After three months of treatment, the music group showed significantly higher Montreal Cognitive Assessment (MoCA) scores compared to the control group (p=0.027), particularly in the domains of delayed recall (p=0.019) and orientation (p=0.023). Moreover, the music group demonstrated significantly better scores in National Institutes of Health Stroke Scale (NIHSS) (p=0.008), Barthel Index (BI) (p=0.019), and Zarit Caregiver Burden Interview (ZBI) (p=0.008) compared to the control group. No effects were found on mood as measured by the Hamilton Anxiety Rating Scale (HAMA) and the Hamilton Depression Rating Scale (HAMD).
CONCLUSIONS: Personalized music listening promotes the recovery of cognitive and neurological functions, improves ADLs, and reduces caregiver burden in patients with PSCI.