■失语症评估主要检查个人的语法,名词,和动词。然而,修饰符,如形容词和数字词,对于失语症患者来说,绑定语素可能是相当困难的主题。形态句法生成(MorGen)针对名词,修饰符,以及在失语症患者中的两个单词短语中绑定的屈折词素。
■这项工作的目的是提供MorGen在超急性-急性失语症中的第一份报告。在这样做的时候,我们的目标是(1)检验MorGen与常见失语症评估的并行有效性;(2)描述急性失语症患者在修饰语中的表现;(3)将MorGen表现与急性卒中患者血管病变程度联系起来。
■在左半球缺血性中风的前14天内,有62名成人讲英语的人和61名健康对照参与者完成了MorGen。除了收到MorGen,中风参与者接受了西方失语症电池(WAB),波士顿命名测试,和霍普金斯行动命名评估。临床MRI分析了左前血管区域的病变程度,中间,和大脑后动脉,以及左后脉络膜和丘脑动脉。
■目标1:MorGen的性能一直很高,与WAB上的显著相关性,波士顿命名测试,和霍普金斯行动命名评估。目标2:在WAB上中风但在功能限制(WFL)内的个体在MorGen上的表现明显比健康对照差,由形容词表现的差异驱动。当控制失语症严重程度时,那些流利的失语症患者在产生名词方面表现明显更好,复数,number,尺寸,和颜色比那些有非流利失语症的人,但两组都倾向于省略基因标记。目的3:大脑后动脉颞支区域的病变与名词表现较差有关,尺寸,和颜色。大脑前动脉区域的病变与数量表现较差有关。
■这项工作强调了MorGen作为笔划后语言评估工具的价值,该工具补充了WAB和BNT等更广泛使用的评估中捕获的技能。
UNASSIGNED: Aphasia assessment primarily examines an individual\'s syntax, nouns, and verbs. However,
modifiers, such as adjectives and number words, and bound morphemes can be the subject of considerable difficulty for individuals with aphasia. The Morphosyntactic Generation (MorGen) targets nouns,
modifiers, and bound inflectional morphemes in two-word phrases among people with aphasia.
UNASSIGNED: The purpose of this work is to provide the first report of the MorGen in hyperacute-acute aphasia. In doing so, we aim to (1) examine the MorGen\'s concurrent validity with common assessments of aphasia; (2) describe performance in
modifiers by people with acute aphasia; and (3) associate MorGen performance with extent of lesioned vascular territories in acute stroke.
UNASSIGNED: 62 adult English speakers within the first 14 days of left hemisphere ischemic stroke and 61 healthy control participants completed the MorGen. In addition to receiving the MorGen, participants with stroke received the Western Aphasia Battery (WAB), Boston Naming Test, and Hopkins Action Naming Assessment. Clinical MRIs were analyzed for the extent of lesion in the vascular territory of the left anterior, medial, and posterior cerebral artery, as well as the left posterior choroidal and thalamoperforator arteries.
UNASSIGNED: Aim 1: Performance on the MorGen demonstrated consistently high, significant correlations with that on the WAB, Boston Naming Test, and Hopkins Action Naming Assessment. Aim 2: Individuals who had a stroke but were within functional limits (WFL) on the WAB performed significantly worse than healthy controls on the MorGen, driven by differences in adjective performance. When controlling for aphasia severity, those with fluent aphasia performed significantly better in their production of nouns, plurals, number, size, and color than those who had non-fluent aphasia, but both groups were similarly inclined to omit genitive marking. Aim 3: Lesions in the territory of the temporal branch of the posterior cerebral artery were associated with poorer performance in nouns, size, and color. Lesions in the territory of the anterior cerebral artery were associated with poorer performance in numbers.
UNASSIGNED: This work highlights the value of the MorGen as a tool for post-stroke language evaluation that complements the skills captured in more widely-used assessments such as the WAB and BNT.