middle ear inflammation

  • 文章类型: English Abstract
    BACKGROUND: An increasing number of pediatric patients with mastoiditis and a consequent increase in mastoidectomy rates was noted in 2022 and 2023.
    OBJECTIVE: This study aimed to analyze the increase in the number of children presenting with mastoiditis and subsequent mastoidectomy, to assess correlations with prior antibiotic treatment or COVID-19 infection, and to provide an overview of involved pathogens, treatment, and disease course.
    METHODS: A retrospective analysis of all patients with mastoidectomy since 2012 was conducted. Data collected comprised type and duration symptoms, prior antibiotic therapy, diagnostic tests and disease course, causal pathogens, length of hospitalization, and complications.
    RESULTS: A highly significant increase in mastoidectomies in children could be demonstrated from 2022. Neither the pathogens involved nor the course of disease or complications showed differences. An increase in the number of patients with prior outpatient antibiotic therapy could be shown. About a half of the patients becoming ill after fall 2022 had a positive history of COVID. Hyperplasia of adenoid tissue was a far less frequent causal mechanism than in the years before COVID.
    CONCLUSIONS: No clear correlation with reduced outpatient antibiotic therapy could be found. Whether there exists an association with prior COVID infection cannot be judged at this time, due to the high number of asymptomatic and therefore unknown COVID infections.
    UNASSIGNED: HINTERGRUND: In den Jahren 2022 und 2023 wurde eine steigende Anzahl an Mastoiditiden bei Kindern und damit auch ein Anstieg der Mastoidektomien bei Kindern beobachtet.
    UNASSIGNED: Ziel der vorliegenden Arbeit war es, den Anstieg der Anzahl an Patienten mit Mastoiditis und folgender Mastoidektomie zu analysieren, Korrelationen mit vorheriger Antibiotikatherapie und COVID-Infektionen zu untersuchen und einen Überblick über Keimspektrum, Krankheitsverlauf und Therapie zu geben.
    METHODS: Dazu wurde eine retrospektive Analyse aller seit 2012 behandelten Patienten mit Mastoiditis durchgeführt, bei denen eine Mastoidektomie durchgeführt werden musste. Evaluiert wurden Art und Dauer vorangegangener Symptome und einer vorherigen Antibiotikatherapie, Diagnostik und Krankheitsverlauf sowie Keimspektrum, Dauer des Krankenhausaufenthalts und Komplikationen.
    UNASSIGNED: Es wurde ein hoch signifikanter Anstieg an Mastoiditiden und somit auch an Mastoidektomien ab 2022 gezeigt. Weder Keimspektrum noch Krankheitsverlauf oder Komplikationsrate unterschieden sich von den vorherigen Jahren mit niedrigerer Inzidenz. Eher konnte eine Zunahme bereits ambulant antibiotisch vortherapierter Patienten gezeigt werden. Etwa die Hälfte der seit Herbst 2022 erkrankten Patienten hatte eine positive COVID-Anamnese. Adenoidhyperplasie spielte ursächlich eine deutlich geringere Rolle als in den Jahren zuvor.
    UNASSIGNED: Eine Korrelation zu reduzierter ambulanter Antibiotikagabe erscheint bei in diesem Kollektiv eher steigender Anzahl somit kausal als unwahrscheinlich. Ob ein Zusammenhang mit einer durchgemachten COVID-Infektion besteht, kann aufgrund der hohen Dunkelziffer bei asymptomatischen und nicht nachgewiesenen Fällen nicht abschließend beurteilt werden.
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  • 文章类型: Journal Article
    促进先天性外耳道狭窄合并外耳道胆脂瘤患儿术后恢复的最佳手术时机,容易受到中耳和乳突渗出性炎症的影响,仍然不确定。
    探讨先天性外耳道狭窄合并外耳道胆脂瘤伴渗出性炎症的治疗方法。
    45例先天性外耳道狭窄伴外耳道胆脂瘤合并乳突炎患者的回顾性分析.根据手术时积液是否已经消退,将患者分为两组。两组均在手术前后进行纯音测听测试。
    第1组术后干耳的平均持续时间为36.38天,第2组为47.90天(p<0.05)。在接受听力重建的患者中,第1组的平均空气传导阈值降低了15-36dBHL,第2组的平均空气传导阈值降低了7-22dBHL(p<0.05)。
    在先天性外耳道狭窄伴外耳道胆脂瘤渗出性炎症的情况下,通过在渗出性消退后进行手术可以增强干耳和听力改善的术后效果。
    UNASSIGNED: The optimal timing for surgery to promote postoperative recovery in children with congenital stenosis of the external auditory canal with external auditory canal cholesteatoma, who are susceptible to exudative inflammation of middle ear and mastoid process, is still uncertain.
    UNASSIGNED: To investigate the treatment of congenital stenosis of external auditory canal with external auditory canal cholesteatoma complicated with exudative inflammation.
    UNASSIGNED: A retrospective analysis of 45 patients with congenital stenosis of external auditory canal with external auditory canal cholesteatoma complicated with mastoiditis. Based on whether effusion had resolved at the time of surgery, the patients were divided into two groups. Pure-tone audiometry tests were performed before and after surgery for both groups.
    UNASSIGNED: The average postoperative duration of dry ear was 36.38 days in Group 1 and 47.90 days in Group 2 (p < 0.05). Among patients who underwent hearing reconstruction, the average air conduction threshold decreased by 15-36 dBHL in Group 1 and by 7-22 dBHL in Group 2 (p < 0.05).
    UNASSIGNED: The postoperative outcomes of dry ear and hearing improvement can be enhanced by performing operation after effusion resolution in cases of congenital external auditory canal stenosis with external auditory canal cholesteatoma exudative inflammation.
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  • 文章类型: Journal Article
    评估和比较接受人工耳蜗植入(CI)并在术前或术中放置鼓膜切开术管(MT)的儿童与没有MT的儿童。
    这是对2015年至2020年在三级护理儿科医院接受CI治疗的儿科患者的回顾性研究。对有或没有MT的CI患者进行了以下结果的回顾:术中发现,术中和术后并发症,和手术时间。进行描述性和双变量统计分析。
    192例人工耳蜗植入手术:116例无MT管,76例有MT病史。26例患者在CI手术时存在MT。MT组(CI+MT组)和无MT组(CI-MT组)在术中并发症(P=0.760)和术中结果(P=0.545)方面无统计学差异。MT与术后总并发症(GEE)的相关性无统计学意义(OR2.45,95%CI0.83-7.22,P值0.105)。CI+MT患者手术时中耳粘膜发炎的可能性显著增加(P=0.003)。与CI-MT组相比,CI+MT患者没有更长的手术时间(3.47hvs3.3h,分别,P=0.342)。
    我们的数据证实在鼓膜切开术的耳朵中进行CI是安全的,尽管外科医生应该意识到在手术过程中可能会遇到中耳炎症的增加。
    UNASSIGNED: To evaluate and compare children undergoing cochlear implantation (CI) with myringotomy tubes (MT) placed preoperatively or intraoperatively to those without MT .
    UNASSIGNED: This was a retrospective review of pediatric patients undergoing CI between 2015 to 2020 at a tertiary care pediatric hospital. CI patients with and without MT were reviewed for the following outcomes: intraoperative findings, intraoperative and postoperative complications, and surgical time. Descriptive and bivariable statistical analysis was performed.
    UNASSIGNED: 192 cochlear implant surgeries were included: 116 without MT tubes and 76 with a history of MT. Twenty-six patients had MT present at the time of CI surgery. No statistical difference existed between patients with MT (CI + MT group) and those without MT (CI - MT group) with regard to intraoperative complications (P = 0.760) and intraoperative findings (P = 0.545). MT association with total post-operative complications (GEE) showed no statistical significance (OR 2.45, 95% CI 0.83-7.22, P-value 0.105). CI + MT patients were significantly more likely to have inflamed middle ear mucosa at time of surgery (P = 0.003). CI + MT patients did not have a longer length of surgery compared to the CI - MT group (3.47 h vs 3.3 h, respectively, P = 0.342).
    UNASSIGNED: Our data confirms it is safe to perform CI in ears with myringotomy tubes, although the surgeon should be aware of possibly encountering increased middle ear inflammation during the surgery.
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  • 文章类型: Journal Article
    急性中耳炎(AOM)是儿童最常见的耳鼻喉科疾病之一。在抗生素/后抗生素时代,面瘫是AOM非常罕见的并发症(0.004-0.005%)。尽管这种并发症很少,所有医生都应该知道正确的治疗管理,以避免严重的后遗症。这篇综述的目的是提供基于当前文献的管理指南。
    方法:选择了2000年至2022年发表的15项研究,包括120例患者(62M/58F),平均年龄4.96岁(范围=4个月-16岁;SD:4.2)。瘫痪通常突然发作,严重程度(发病时的中House-Brackmann(HB)评分:4.68;SD:0.5);但是,大多数患者倾向于几乎完全恢复(随访时HB1占88.49%).
    结果:其一线治疗必须基于使用抗生素(β-内酰胺类抗生素作为青霉素或头孢菌素)。皮质类固醇应同时用于抗炎和神经保护作用;然而,作者之间对他们的申请没有一致意见。鼓膜切开术,有或没有通风管插入,在鼓膜完整的情况下表示。即使在临床治疗中,也只能在AOM症状恶化或HB评分恶化的患者中进行其他类型的手术。
    结论:获得的数据表明,保守治疗足以使大多数患者完全康复,它是首选的一线治疗。仅在急性乳突炎且保守治疗后症状无改善的患者中应进行乳突切除术。目前文献中的数据不足以为需要进行面神经减压的乳突切除术的患者提供明确的选择标准。这种治疗的选择是基于个人中心的专业知识。需要进一步的研究来阐明皮质类固醇的作用和面神经减压在这种临床情况下的作用。
    Acute otitis media (AOM) is one of the most common ENT diseases in children. In the antibiotic/post-antibiotic era, facial paralysis is a very rare complication of AOM (0.004-0.005%). Despite the rarity of this complication, it should be known by all physicians for proper therapeutic management to avoid serious sequelae. The aim of this review is to provide a management guide based on the current literature.
    METHODS: Fifteen studies published between 2000 and 2022 were selected, including 120 patients (62 M/58 F) with an average age of 4.96 years old (range = 4 months-16 years; SD: 4.2). The paralysis frequently has a sudden onset and is of a severe grade (medium House-Brackmann (HB) score at onset: 4.68; SD: 0.5); however, it tends to have an almost complete recovery in most patients (88.49% HB 1 at follow-up).
    RESULTS: Its first-line treatment must be based on the use of antibiotics (beta-lactam antibiotics as penicillins or cephalosporins). Corticosteroids should be used concomitantly for their anti-inflammatory and neuroprotective actions; however, there is no unanimity between authors about their application. Myringotomy, with or without ventilation tube insertion, is indicated in cases where the tympanic membrane is intact. Other kinds of surgery should be performed only in patients who have a worsening of their AOM symptoms or a worsening in HB score even with clinical treatment.
    CONCLUSIONS: The obtained data show that a conservative treatment can be sufficient for complete recovery in most patients, and it is preferred as the first-line therapy. Mastoidectomy should be performed only in patients with acute mastoiditis and without symptom improvement after a conservative approach. There are insufficient data in the current literature to provide clear selection criteria for patients who need to undergo mastoidectomy with facial nerve decompression. The choice of this treatment is based on an individual center expertise. Further studies are needed to clarify the role of corticosteroids and the role of facial nerve decompression in this clinical scenario.
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