microdiscectomy

显微椎间盘切除术
  • 文章类型: English Abstract
    The problem of patients\' rehabilitation after spinal surgery remains relevant. The use of therapeutic physical factors, both preformed and natural, including pelotherapy, is very important. The application of the latter requires to develop new techniques in this pathology, one of which is low temperature exposure.
    OBJECTIVE: To study the possibility and to assess the effectiveness of resource-saving nonthermal pelotherapy techniques in patients\' rehabilitation, who underwent surgeries for intervertebral discs\' herniation.
    METHODS: The number of patients equal 88, including 39 males and 49 females, after lumbar microdiscectomy, was examined in this study. The patients were divided into 3 groups. Control group (28 patients) received a basic rehabilitation complex (therapeutic gymnastics, massage, low-frequency magnetotherapy); the 1st study group (30 patients) - basic complex and procedures of thin layer applications with peat muds preparation (Tomed-applikat) at 20-24 °C; the 2nd study group (30 patients) - basic complex and procedures of fluctuoresis of 2% solution of peat mud Tomed-aqua preparation.
    RESULTS: There was a significant reduction of pain syndrome, recovery of sensitivity and motor activity, decrease of Oswestry index, characterizing the degree of vital activity disturbance, in patients of the study group compared to the control group after treatment.
    CONCLUSIONS: The inclusion of nonthermal resource-saving techniques of pelotherapy in rehabilitation complex of patients who underwent spinal surgery is effective and pathogenetically justified.
    Проблема реабилитации больных после перенесенных оперативных вмешательств на позвоночнике остается актуальной. При этом большое значение имеет применение лечебных физических факторов как преформированных, так и природных, в том числе пелоидотерапии. Использование последней нуждается в разработке новых методик при этой патологии, одной из которых является низкотемпературное воздействие.
    UNASSIGNED: Изучить возможность и оценить эффективность применения ресурсосберегающих нетепловых методик пелоидотерапии в реабилитации больных, перенесших операции по поводу грыжи межпозвонковых дисков.
    UNASSIGNED: В рамках настоящего исследования было обследовано 88 больных, в том числе 39 мужчин и 49 женщин, после выполненной микродискэктомии на уровне поясничного отдела позвоночника. Пациенты были разделены на 3 группы. Контрольная группа (28 пациентов) получала базисный реабилитационный комплекс (лечебная гимнастика, массаж, низкочастотная магнитотерапия); 1-я основная группа (30 пациентов) — базисный комплекс и процедуры тонкослойных аппликаций препарата торфяной грязи (Томед-аппликат) с температурой 20—24 °C; 2-я основная группа (30 пациентов) — базисный комплекс и процедуры флюктуофореза 2% раствора торфяного грязевого препарата Томед-аква.
    UNASSIGNED: У пациентов основных групп, по сравнению с контролем, после проведенного лечения отмечено достоверное уменьшение болевого синдрома, восстановление чувствительности, двигательной активности, уменьшение индекса Освестри, характеризующего степень нарушений жизнедеятельности.
    UNASSIGNED: Включение в комплекс реабилитации пациентов после операций на позвоночнике нетепловых ресурсосберегающих методик пелоидотерапии является эффективным и патогенетически обоснованным.
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  • 文章类型: Journal Article
    背景:量化接受管状微盘切除术和常规开放微盘切除术的患者的脂肪浸润和椎旁肌肉变性程度。
    方法:在保守治疗失败后,对腰椎间盘突出症患者进行前瞻性队列研究。技术的选择基于外科医生的偏好。使用Goutallier系统和肌肉中脂肪的百分比进行多裂肌的分析。术前和术后1年使用T2加权磁共振成像,统计学分析采用Wilcoxon检验和Spearman相关性检验,显著性水平为5%。
    结果:32例患者被纳入研究。术后1年,脊柱两侧肌肉脂肪浸润百分比增加,尽管在接受常规显微椎间盘切除术的患者中,只有同侧表现出统计学意义(术前为43.3%,术后为57.8%)。根据两种干预措施的Goutallier分类(1-2级),椎间盘突出症的同侧肌肉变性显着增加。在方法的比较分析中,脂肪浸润评分或多裂肌变性程度均未发现统计学上的显着差异。
    结论:腰椎间盘突出症手术导致的肌肉损伤显著增加了脂肪浸润和多裂的变性。肌肉变性与背痛恶化有关。
    结论:虽然技术之间没有发现显著差异,管状微创方法显示出减少肌肉损伤的趋势。这些发现强调了在手术过程中减少肌肉损伤以改善术后恢复和长期预后的重要性。
    方法:
    BACKGROUND: To quantify fatty infiltration and degree of paraspinal muscle degeneration in patients submitted to tubular microdiscectomy and conventional open microdiscectomy.
    METHODS: A prospective cohort of patients was submitted to microdiscectomy for lumbar disc herniation after failure of conservative treatment. Selection of the technique was based on the surgeon\'s preference. Analysis of the multifidus muscle was performed using the Goutallier system and the percentage of fat in the muscle. Preoperative and 1-year postoperative T2-weighted magnetic resonance imaging was used, and statistical analysis was carried out using the Wilcoxon test and Spearman correlation test using a significance level of 5%.
    RESULTS: Thirty-two patients were included in the study. The percentage of fatty infiltration in the muscle increased on both sides of the spine 1 year after surgery, although only the ipsilateral side presented statistical significance in patients submitted to conventional microdiscectomy (43.3% preoperative and 57.8% postoperative). Muscular degeneration increased significantly ipsilateral to the disc herniation according to the Goutallier classification (grades 1-2) for both interventions. No statistically significant difference was found for fatty infiltration scores or for the degree of muscular degeneration of the multifidus in the comparative analysis of the methods.
    CONCLUSIONS: Muscular damage resulting from surgery of lumbar disc herniation significantly increases fatty infiltration and degeneration of the multifidus. Muscular degeneration was associated with worsening back pain.
    CONCLUSIONS: While no significant difference was found between the techniques, the tubular minimally invasive approach shows a tendency for less muscle damage. These findings highlight the importance of minimizing muscle injury during surgery to improve postoperative recovery and long-term outcomes.
    METHODS:
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  • 文章类型: Journal Article
    北美脊柱学会(NASS)组装了第一个用于描述腰椎间盘疾病的综合命名系统,包括腰椎间盘突出症。这项研究的目的是(1)确定哪些NASS描述符最能预测显微椎间盘切除术后独立患者报告的结果,以及(2)确定每个NASS描述符的评估者间可靠性。
    对2014-2021年接受腰椎显微椎间盘切除术的成年患者(≥18岁)进行回顾性分析。术前收集患者报告的结果指标(PROM),3个月,和术后1年的时间点。使用针对椎间盘突出的NASS腰椎间盘命名法在术前MRI上对腰椎间盘突出症进行评估和分类。
    最终分析中包括了大约213例显微椎间盘切除术患者。表现出最大可靠性的疝气描述符包括隔离状态(κ=0.83),轴向椎间盘突出面积(κ=0.83),和侧向性(κ=0.83)。评分者间可靠性最低的描述符是迁移方向(κ=0.53)。3个月时,隔离疝与ODI(p=.004)和MCS(p=.032)的最小临床重要差异(MCID)的几率较低相关.12个月时,Oswestry残疾指数(ODI)MCID成就也观察到类似的趋势(p=.001)。3个月时,具有较大轴向面积的突出是ODI(p=.004)和心理分量总结(MCS)(p=.009)的MCID成就的预测因子。这两个协会都在12个月时持续存在;然而,较大的轴向椎间盘突出面积能够预测12个月时视觉模拟评分(VAS)腿部的MCID成就(p=0.031)。
    NASS命名系统在预测显微椎间盘切除术后结局方面的实用性还有待研究。我们表明,隔离状态和椎间盘面积都是可靠的,并且能够预测在手术后3个月和12个月的某些临床结果中实现MCID的几率。因此,腰椎间盘突出症的术前影像学分析可能有助于准确设定患者的期望.
    UNASSIGNED: The North American Spine Society (NASS) assembled the first ever comprehensive naming system for describing lumbar disc disease, including lumbar disc herniation. The objectives of this study were (1) to determine which NASS descriptors are most predictive of independent patient-reported outcomes after microdiscectomy and (2) to identify the inter-rater reliability of each NASS descriptor.
    UNASSIGNED: Adult patients (≥18 years) who underwent a lumbar microdiscectomy from 2014-2021 were retrospectively identified. Patient-reported outcome measures (PROMs) were collected at preoperative, 3-month, and 1-year postoperative time points. Lumbar disc herniations were evaluated and classified on preoperative MRI using the NASS lumbar disc nomenclature specific to disc herniation.
    UNASSIGNED: About 213 microdiscectomy patients were included in the final analysis. Herniation descriptors exhibiting the greatest reliability included sequestration status (κ=0.83), axial disc herniation area (κ=0.83), and laterality (κ=0.83). The descriptor with the lowest inter-rater reliability was direction of migration (κ=0.53). At 3 months, a sequestered herniation was associated with lower odds of achieving the minimal clinically important difference (MCID) for ODI (p=.004) and MCS (p=.032). At 12 months, a similar trend was observed for Oswestry Disability Index (ODI) MCID achievement (p=.001). At 3 months, a herniation with larger axial area was a predictor of MCID achievement in ODI (p=.004) and the mental component summary (MCS) (p=.009). Neither association persisted at 12 months; however, larger axial disc herniation area was able to predict MCID achievement in the Visual Analogue Scale (VAS) leg (p=.031) at 12 months.
    UNASSIGNED: The utility of the NASS nomenclature system in predicting postoperative outcomes after microdiscectomy has yet to be studied. We showed that sequestration status and disc area are both reliable and able to predict the odds of achieving MCID in certain clinical outcomes at 3 months and 12 months after surgery. Hence, preoperative imaging analysis of lumbar disc herniations may be useful in accurately setting patient expectations.
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  • 文章类型: Journal Article
    目的:本研究的目的是评估腰椎手术中患者感知的健康变化与常用的患者报告结果指标(PROMs)之间的相关性。
    方法:这是一项前瞻性收集的连续患者的数据的回顾性研究,腰椎减压,或从2017年到2023年在单一学术机构进行腰椎融合。全球变化评级(GRC)问卷之间的相关性,5项Likert量表(更好,稍微好一点,差不多,稍差一点,更糟糕的是),和PROMs(Oswestry残疾指数,背部和腿部疼痛的视觉模拟量表,12项简短形式健康调查身体成分总结和心理成分总结,和PROMIS物理功能)使用Spearman的等级相关系数进行评估。
    结果:总共1871例患者(397例微椎间盘切除术,965次减压,和509融合)被包括在内。每组中的大多数患者在每个术后时间点评估其腰椎状况与术前相比要好得多,并且与先前的随访相比,在每个术后时间点报告了改善的健康状况。从术前时间点开始,GRC与PROM评分的变化之间存在统计学上的显着但弱至中度相关性。GRC与先前访视的PROM评分变化之间的相关性显示出一些统计学上的显着相关性,但是强度从非常弱到弱。
    结论:大多数接受腰椎显微切除术的患者,减压,或融合术在术后早期证实了健康状况的显着改善,并在后期随访中继续改善。然而,常用的PROM与GRC确定的患者感觉到的腰椎相关总体健康状况的变化具有非常弱至中度的相关性。因此,目前使用的PROM在检测这些变化时可能不那么敏感,或者可能无法充分反映对接受腰椎手术的患者有意义的健康状况变化.
    OBJECTIVE: The aim of this study was to assess the correlation between patient-perceived changes in health and commonly utilized patient-reported outcome measures (PROMs) in lumbar spine surgery.
    METHODS: This was a retrospective review of prospectively collected data on consecutive patients who underwent lumbar microdiscectomy, lumbar decompression, or lumbar fusion at a single academic institution from 2017 to 2023. Correlation between the global rating of change (GRC) questionnaire, a 5-item Likert scale (much better, slightly better, about the same, slightly worse, and much worse), and PROMs (Oswestry Disability Index, visual analog scale for back and leg pain, 12-Item Short Form Health Survey Physical Component Summary and Mental Component Summary, and PROMIS physical function) was assessed using Spearman\'s rank correlation coefficients.
    RESULTS: A total of 1871 patients (397 microdiscectomies, 965 decompressions, and 509 fusions) were included. A majority of patients in each group rated their lumbar condition as much better at each postoperative time point compared with preoperatively and reported improved health status at each postoperative time point compared with the previous follow-up visit. Statistically significant but weak to moderate correlations were found between GRC and change in PROM scores from the preoperative time point. Correlation between GRC and change in PROM scores from the prior visit showed some statistically significant correlations, but the strengths ranged from very weak to weak.
    CONCLUSIONS: A majority of patients undergoing lumbar microdiscectomy, decompression, or fusion endorsed notable improvements in health status in the early postoperative period and continued to improve at late follow-up. However, commonly used PROMs demonstrated very weak to moderate correlations with patient-perceived changes in overall lumbar spine-related health status as determined by GRC. Therefore, currently used PROMs may not be as sensitive at detecting these changes or may not be adequately reflecting changes in health conditions that are meaningful to patients undergoing lumbar spine surgery.
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  • 文章类型: Journal Article
    目的:腰椎间盘切除术是美国最常见的脊柱手术,每年执行300,000个程序。像其他外科手术一样,此手术不排除潜在的并发症.本文介绍了一种用于显微椎间盘切除术的视频注释方法,包括手术工作流程的开发。在今后的工作中,这种方法可以与计算机视觉和机器学习模型相结合,以预测潜在的不良事件.这些系统将监测术中活动并可能预测结果。
    方法:监督机器学习方法的一个必要步骤是视频注释,这涉及逐帧标记对象,使它们可被机器学习应用程序识别。脊柱手术的显微椎间盘切除术录像是从多中心研究合作中收集的。这些视频被匿名化并存储在基于云的平台中。视频被上传到在线注释平台。基于文献回顾和手术观察开发了注释框架,以确保对仪器的正确理解,解剖学,和步骤。
    结果:一位外科医生制作了一个带注释的显微椎间盘切除术视频。允许多次迭代创建带有标记的手术工具的带注释的视频,解剖学,和阶段。此外,开发了一个用于培训新手注释者的工作流程,它提供有关注释软件的信息,以帮助生成标准化注释。
    结论:管理手术视频数据的标准化工作流程对于手术视频注释和机器学习应用至关重要。我们开发了一个标准的工作流程,用于注释显微椎间盘切除术的手术视频,这可能有助于使用监督机器学习应用程序对视频进行定量分析。未来的工作将通过开发过程建模和结果预测因子来证明此工作流程的临床相关性和影响。
    OBJECTIVE: Lumbar discectomy is among the most common spine procedures in the US, with 300,000 procedures performed each year. Like other surgical procedures, this procedure is not excluded from potential complications. This paper presents a video annotation methodology for microdiscectomy including the development of a surgical workflow. In future work, this methodology could be combined with computer vision and machine learning models to predict potential adverse events. These systems would monitor the intraoperative activities and possibly anticipate the outcomes.
    METHODS: A necessary step in supervised machine learning methods is video annotation, which involves labeling objects frame-by-frame to make them recognizable for machine learning applications. Microdiscectomy video recordings of spine surgeries were collected from a multi-center research collaborative. These videos were anonymized and stored in a cloud-based platform. Videos were uploaded to an online annotation platform. An annotation framework was developed based on literature review and surgical observations to ensure proper understanding of the instruments, anatomy, and steps.
    RESULTS: An annotated video of microdiscectomy was produced by a single surgeon. Multiple iterations allowed for the creation of an annotated video complete with labeled surgical tools, anatomy, and phases. In addition, a workflow was developed for the training of novice annotators, which provides information about the annotation software to assist in the production of standardized annotations.
    CONCLUSIONS: A standardized workflow for managing surgical video data is essential for surgical video annotation and machine learning applications. We developed a standard workflow for annotating surgical videos for microdiscectomy that may facilitate the quantitative analysis of videos using supervised machine learning applications. Future work will demonstrate the clinical relevance and impact of this workflow by developing process modeling and outcome predictors.
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  • 文章类型: Journal Article
    目的:分析腰椎退行性疾病运动员脊柱外科治疗的结果,并根据腰椎的术前症状和影像学变化制定手术策略。
    方法:本研究纳入了114名腰椎退行性疾病运动员。研究了四个独立的组:(1)显微外科手术/内窥镜椎间盘切除术(n=35);(2)小关节PRP治疗(n=41);(3)全椎间盘置换(n=11);(4)腰椎椎间融合(n=27)。我们评估了术后临床结果和术前放射学结果。术后平均随访5(3;6),3.5(3;5),3(2;4)和4(3;5)年,分别。分析包括对临床结果的评估(最初的临床症状,根据VAS的慢性疼痛综合征水平,根据SF-36问卷的生活质量,根据主观Borg感知锻炼量表对身体活动的耐受程度)和放射学数据(动态滑动,动态分段角度,根据藤原分类的小关节退行性变化和根据Pfirrmann分类的椎间盘退行性变化;使用扩散加权MRI的扩散系数变化)。
    结果:重返运动的中位数和25-75%的四分位数时间为12.6(10.2;14.1),2.8(2.4;3.7),9(6;12),和14(9;17)周,分别。我们检查了所用的手术治疗类型,以及术前临床症状,椎间盘和小关节退行性变化的严重程度,回归体育运动的时机,疼痛综合征的程度,根据SF-36的生活质量和对身体活动的耐受程度。然后,我们根据个体术前神经功能和腰椎形态变化制定了手术策略。
    结论:在这项回顾性研究中,我们报告了四种治疗运动员腰椎退行性疾病的临床结果。为分析的手术技术使用开发的患者选择标准旨在最大程度地减少重返比赛时间。
    OBJECTIVE: To analyze of the results of spine surgical treatment of athletes with lumbar degenerative disease and development of a surgical strategy based on the preoperative symptoms and radiological changes in the lumbar spine.
    METHODS: For 114 athletes with lumbar degenerative disease were included in the present study. Four independent groups were studied: (1) microsurgical/endoscopic discectomy (n = 35); (2) PRP therapy in facet joints (n = 41); (3) total disc replacement (n = 11); (4) lumbar interbody fusion (n = 27). We evaluated postoperative clinical outcomes and preoperative radiological results. The average postoperative follow-up was 5 (3;6), 3.5 (3;5), 3 (2;4) and 4 (3;5) years, respectively. The analysis included an assessment of clinical outcomes (initial clinical symptoms, chronic pain syndrome level according to the VAS, quality of life according to the SF-36 questionnaire, degree of tolerance to physical activity according to the subjective Borg Rating of Perceived Exertion Scale) and radiological data (Dynamic Slip, Dynamic Segmental Angle, degenerative changes in the facet joint according to the Fujiwara classification and disc according to the Pfirrmann classification; changes in the diffusion coefficient using diffusion-weighted MRI).
    RESULTS: The median and 25-75% quartiles timing of return to sports were 12.6 (10.2;14.1), 2.8 (2.4;3.7), 9 (6;12), and 14 (9;17) weeks, respectively. We examined the type of surgical treatment utilized, as well as the preoperative clinical symptoms, severity of degenerative changes in the intervertebral disc and facet joint, the timing of return to sports, the level of pain syndrome, the quality of life according to SF-36, and the degree of tolerance to physical activity. We then developed a surgical strategy based on individual preoperative neurological function and lumbar morphological changes.
    CONCLUSIONS: In this retrospective study, we report clinical results of four treatment options of lumbar spine degenerative disease in athletes. The use of developed patient selection criteria for the analyzed surgical techniques is aimed at minimizing return-to-play times.
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  • 文章类型: Journal Article
    背景:已经开发了用于椎间孔外减压的各种方法和技术,特别是对于远外侧腰椎间盘突出症。在腰椎的上层,明显的解剖学差异是显而易见的,这可能会使相关的手术方法复杂化。本研究旨在确定上腰椎间盘的外侧椎间孔外入路的安全性和有效性。
    方法:将L1-2和L2-3迁移型腰椎间盘突出症定义为上腰椎间盘突出症。回顾性调查了2018年1月至2022年3月期间接受椎间孔外腰椎微髓切除术的31例连续上腰椎间盘突出症患者。使用间隔病史对患者进行评估,随访下背部和腿部疼痛视觉模拟量表评分(0-100mm),Oswestry残疾指数(%),并修改了MacNab标准。
    结果:31例连续上腰椎间盘突出症患者(男20例,女11例),平均年龄为52.8±10.8岁(范围31-70岁),接受了椎间孔外腰椎微髓切除术。术前、术后视觉模拟评分及ODI差异有统计学意义(P<0.001)。根据修改后的MacNab标准,23例患者表现出极好的改善,5显示出良好的改善,3显示出相当的改善;因此,在2年的随访中,令人满意的改善率为90.3%。在随访期间,没有患者需要在手术水平上再次手术。
    结论:椎间孔外腰椎显微摘除术是治疗上腰椎间盘突出症的一种安全、有效的微创手术技术。
    BACKGROUND: Various methods and techniques have been developed for extraforaminal decompression, particularly for far lateral lumbar disc herniation. Distinct anatomical differences are noticeable in the upper levels of the lumbar spine, which may complicate the related surgical approach. This study aimed to determine the safety and efficiency of the far lateral extraforaminal approach for the upper lumbar disc.
    METHODS: L1-2 and L2-3 migrated lumbar disc herniations were defined as upper lumbar disc herniations. 31 consecutive patients with upper lumbar disk herniation who underwent extraforaminal lumbar microdiscectomy between January 2018 and March 2022 were retrospectively investigated. The patients were assessed using the interval history, follow-up lower back and leg pain visual analog scale scores (0-100 mm), the Oswestry Disability Index (%), and modified MacNab criteria.
    RESULTS: 31 consecutive patients with upper lumbar disk herniation (20 men and 11 women) with a mean age of 52.8 ± 10.8 years (range 31-70 years) underwent extraforaminal lumbar microdiscectomy. The preoperative and postoperative visual analog scale scores and Oswestry Disability Index were significantly different (P < 0.001). According to the modified MacNab criteria, 23 patients showed excellent improvement, 5 showed good improvement, and 3 showed fair improvement; thus, the rate of satisfactory improvement was 90.3% at the 2-year follow-up. No patients required reoperation at the operative level during follow-up.
    CONCLUSIONS: Extraforaminal lumbar microdiscectomy is a safe and effective minimally invasive surgical technique for treating upper lumbar disc herniation.
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  • 文章类型: Journal Article
    介绍复发性腰椎间盘突出症(RLDH)的发生率,并确定导致腰椎间盘突出症(LDH)治疗后复发的放射学和患者相关危险因素。
    在2013年1月至2021年12月之间,1214例接受LDH显微椎间盘切除术的患者被纳入这项回顾性研究。患者分为两组,复发组和非复发组,和他们的人口统计,记录临床和放射学特征.通过单变量和多变量逻辑回归分析评估变量与RLDH之间的关联。
    复发组(51.48±13.63)和非复发组(50.38±14.53)的平均年龄相似(p=0.232)。男性占复发组的59.6%和非复发组的49.8%(p=0.002)。多变量逻辑回归显示,作为男性(p=0.009),糖尿病(p=0.038),吸烟(p<0.001),4级和5级椎间盘退变(p<0.001),并且突出(p=0.002),挤压LDH(p<0.001),中心旁(p=0.008)和椎间孔LDH(p=0.008)与复发独立相关。
    为了减少RLDH频率并需要进行翻修手术,在初次手术前后,应尽量减少可改变的危险因素。此外,在具有不可改变的危险因素的患者中,应明确告知患者复发风险,并考虑可能的替代治疗方法.
    UNASSIGNED: To present the incidence of recurrent lumbar disc herniation (RLDH) and to identify radiological and patient-related risk factors that lead to recurrence after lumbar disc herniation (LDH) treatment with microdiscectomy.
    UNASSIGNED: Between January 2013 and December 2021, 1214 patients who had undergone microdiscectomy for LDH were included in this retrospective study. Patients were divided into two groups, the recurrent group and the non-recurrent group, and their demographic, clinical and radiologic characteristics were recorded. The association between the variables and RLDH was assessed by univariate and multivariable logistic regression analyses.
    UNASSIGNED: Mean ages were similar in the recurrent (51.48 ± 13.63) and non-recurrent(50.38 ± 14.53) groups (p=0.232). Males represented 59.6% of the recurrent group and 49.8% of the non-recurrent group (p=0.002). Multivariable logistic regression revealed that being a male (p=0.009), diabetes mellitus (p=0.038), smoking (p<0.001), grade 4&5 disc degeneration (p<0.001), and having protruded (p=0.002), extruded LDH (p<0.001), paracentral (p=0.008) and foraminal LDH (p=0.008) were independently associated with recurrence.
    UNASSIGNED: To reduce RLDH frequency and need for revision surgery, modifiable risk factors should be minimized before and after the initial surgery. Also, in patients with unmodifiable risk factors, patients should be clearly informed about the risk for recurrence and possible alternative treatment methods should be considered.
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  • 文章类型: Journal Article
    背景:邻近节段疾病(ASD)是已知的胸腰椎器械融合的后遗症。对于保守措施失败的顽固性症状患者,可以选择各种手术方法来解决ASD。然而,症状性ASD的最佳治疗策略尚未确定.我们使用不同的手术干预治疗有症状的ASD检查了几种临床结果。
    方法:对2011年10月至2022年2月期间接受胸腰椎ASD翻修手术的连续系列患者进行回顾性回顾。患者接受内镜减压治疗(N=17),显微椎间盘切除术(N=9),腰椎外侧椎间融合术(LLIF;N=26),或开放椎板切除术和融合(LF;N=55)。组间比较的主要结果是再次手术率和2周时腿部和背部的数字疼痛评分,10周,6个月,术后12个月。次要结果包括重新手术的时间,估计失血量,和逗留时间的长短。
    结果:在257例因症状性ASD而接受翻修手术的患者中,107例患者符合纳入标准,至少随访1年。所有患者的平均年龄为67.90±10.51岁。各组之间的年龄差异无统计学意义,性别,术前美国麻醉医师协会评分,以前融合的水平的数量,或术前数字腿部和背部疼痛评分。LF组(12.7%)和LLIF组(19.2%)的再手术率明显低于显微椎间盘切除术(33%)和内镜减压术(52.9%;P=0.005)。在所有4次随访中,只有LF和LLIF队列的疼痛评分显着下降(2周,10周,6个月,和12个月;相对于术前评分,分别为P<0.001和P<0.05)。
    结论:症状性ASD通常需要翻修手术治疗。融合手术(独立的外侧椎间或带器械的后外侧)在减轻疼痛和避免在翻修手术后的前12个月内进行其他翻修方面最有效和持久。
    结论:这项研究强调了对患者进行风险分层的重要性,以确定治疗其症状并降低未来手术风险的侵入性最小的方法。
    方法:
    BACKGROUND: Adjacent segment disease (ASD) is a known sequela of thoracolumbar instrumented fusions. Various surgical options are available to address ASD in patients with intractable symptoms who have failed conservative measures. However, the optimal treatment strategy for symptomatic ASD has not been established. We examined several clinical outcomes utilizing different surgical interventions for symptomatic ASD.
    METHODS: A retrospective review was performed for a consecutive series of patients undergoing revision surgery for thoracolumbar ASD between October 2011 and February 2022. Patients were treated with endoscopic decompression (N = 17), microdiscectomy (N = 9), lateral lumbar interbody fusion (LLIF; N = 26), or open laminectomy and fusion (LF; N = 55). The primary outcomes compared between groups were re-operation rates and numeric pain scores for leg and back at 2 weeks, 10 weeks, 6 months, and 12 months postoperation. Secondary outcomes included time to re-operation, estimated blood loss, and length of stay.
    RESULTS: Of the 257 patients who underwent revision surgery for symptomatic ASD, 107 patients met inclusion criteria with a minimum of 1-year follow-up. The mean age of all patients was 67.90 ± 10.51 years. There was no statistically significant difference between groups in age, gender, preoperative American Society of Anesthesiologists scoring, number of previously fused levels, or preoperative numeric leg and back pain scores. The re-operation rates were significantly lower in LF (12.7%) and LLIF cohorts (19.2%) compared with microdiscectomy (33%) and endoscopic decompression (52.9%; P = 0.005). Only LF and LLIF cohorts experienced significantly decreased pain scores at all 4 follow-up visits (2 weeks, 10 weeks, 6 months, and 12 months; P < 0.001 and P < 0.05, respectively) relative to preoperative scores.
    CONCLUSIONS: Symptomatic ASD often requires treatment with revision surgery. Fusion surgeries (either stand-alone lateral interbody or posterolateral with instrumentation) were most effective and durable with respect to alleviating pain and avoiding additional revisions within the first 12 months following revision surgery.
    CONCLUSIONS: This study emphasizes the importance of risk-stratifying patients to identify the least invasive approach that treats their symptoms and reduces the risk of future surgeries.
    METHODS:
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  • 文章类型: Journal Article
    目的:复发性腰椎间盘突出症(RLDH)是初次椎间盘切除术后常见且具有挑战性的并发症。本研究旨在探讨初始椎间盘组织和复发椎间盘组织的组织病理学结果之间的关系。方法:这项研究调查了70例接受了显微椎间盘切除术并随后发生相同水平的同侧腰椎间盘突出症(LDH)复发的患者。诊所,westernblot,对初始LDH和RLDH患者进行免疫组织化学评估并进行统计学分析。结果:证实了炎症和细胞凋亡在椎间盘疝的退行性改变中的作用以及RLDH组织病理学发现的增加。椎间盘疝组织的退变是一个主要的病理进程,其特征是细胞凋亡,炎症,减少细胞外基质的合成。目前,目前尚无针对椎间盘退变逆转的临床治疗方法。结论:这,因此,远离在椎间盘突出症的干预中增加炎症的因素,申请减少炎症的药物,可以减少椎间盘胶原变性,更成功的结果。这些发现可能为椎间盘退变的机制提供新的思路,并为早期和复发性LDH的治疗提供新的策略。
    UNASSIGNED: Recurrent lumbar disc hernia (RLDH) is a common and challenging complication after an initial discectomy. This study aimed to investigate the relationship between the histopathologic outcomes of the initial and recurrent disc tissues.
    UNASSIGNED: This study investigated 70 patients who underwent a microdiscectomy and subsequently developed same-level same-side lumbar disc herniation (LDH) recurrence. The clinic, western blot, and immunohistochemical evaluations of patients with initial LDH and RLDH were conducted and statistically analyzed.
    UNASSIGNED: The effect of inflammation and apoptosis in the degenerative changes of intervertebral disc hernia and increased histopathologic findings in RLDH was demonstrated. The degeneration of the hernia disc tissue is a major pathological process, which is characterized by cellular apoptosis, inflammation, and reduced synthesis of extracellular matrix. Currently, there is no clinical therapy targeting the reversal of disc degeneration.
    UNASSIGNED: This, therefore, stay away from factors that increase inflammation in the intervention of intervertebral disc hernia, applying to reduce inflammation the medicines, could allow reducing disc collagen degeneration, and more successful outcomes. These findings might shed some new lights on the mechanism of disc degeneration and provide new strategies for the treatments of initial and recurrent LDH.
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