In green biological synthesis, metal nanoparticles are produced by plants or microorganisms. Since it is ecologically friendly, economically viable and sustainable, this method is preferable to other traditional ones. For their continuous groundbreaking advancements and myriad physiochemical and biological benefits, nanotechnologies have influenced various aspects of scientific fields. Metal nanoparticles (MNPs) are the field anchor for their outstanding optical, electrical and chemical capabilities that outperform their regular-sized counterparts. This review discusses the most current biosynthesized metal nanoparticles synthesized by various organisms and their biological applications along with the key elements involved in MNP green synthesis. The review is displayed in a manner that will impart assertiveness, help the researchers to open questions, and highlight many points for conducting future research.
Metal nanoparticles are small sized particles with diameters ranging from 1 to 100 nm. These particles have favorable characteristics that made them substitute regular sized particles in various industrial fields. They can be prepared chemically or physically or biologically. Biological preparation of metal nanoparticles which is also known as green synthesis involves the use of different microbes and plant species. It\'s more beneficial than chemical and physical preparative methods, as it\'s considered cheap and environmentally sustainable. This review will summarize different forms of green synthesis of metal nanoparticles and their application in biomedical field.

Nanotherapeutics are gaining traction in the modern scenario because of their unique and distinct properties which separate them from macro materials. Among the nanoparticles, metal NPs (MNPs) have gained importance due to their distinct physicochemical and biological characteristics. Peptides also exhibit several important functions in humans. Different peptides have received approval as pharmaceuticals, and clinical trials have been commenced for several peptides. Peptides are also used as targeting ligands. Considering all the advantages offered by these two entities, the conjugation of MNPs with peptides has emerged as a potential strategy for achieving successful targeting, diagnosis, and therapy of various neurological pathologies.

Photocatalysis has been known as one of the promising technologies due to its eco-friendly nature. However, the potential application of many photocatalysts is limited owing to their large bandgaps and inefficient use of the solar spectrum. One strategy to overcome this problem is to combine the advantages of heteroatom-containing supports with active metal centers to accurately adjust the structural parameters. Metal nanoparticles (MNPs) and single atom catalysts (SACs) are excellent candidates due to their distinctive coordination environment which enhances photocatalytic activity. Metal-organic frameworks (MOFs), covalent organic frameworks (COFs) and carbon nitride (g-C3 N4 ) have shown great potential as catalyst support for SACs and MNPs. The numerous combinations of organic linkers with various heteroatoms and metal ions provide unique structural characteristics to achieve advanced materials. This review describes the recent advancement of the modified MOFs, COFs and g-C3 N4 with SACs and NPs for enhanced photocatalytic applications with emphasis on environmental remediation.

Consideration of lichen organisms as the ecofriendly source of metal nanoparticles (MNPs) and metal oxide NPs (MONPs) synthesis is seldom. In this study, Ag and Cu MNPs as well as TiO2, ZnO, and Fe3O4 MONPs were green synthesized by Protoparmeliopsis muralis lichen aqueous extract. First, physicochemical characterization by UV-vis spectroscopy, XRD, FT-IR, FESEM, and TEM techniques demonstrated the presence possibility of secondary metabolites around formed MNPs/MONPs with different diameters and shapes (spherical, triangular, polyhedral, and cubic). The antibacterial, antibiofilm, antiquorum sensing, and antioxidant abilities of these MNPs/MONPs against multi drug resistant (MDR) bacterium (Staphylococcus aureus ATCC 43300) and reference bacteria (Escherichia coli ATCC 25922 and Pseudomonas aeruginosa ATCC 27853) were then evaluated by in vitro tests. Results of disc diffusion and MIC/MBC assays of Ag NPs as an effective antibacterial agent illustrated a higher sensitivity of the P. aeruginosa pathogen than E. coli and S. aureus. In next steps, a significant reduction was observed in the biofilm formation of each bacterium and pyocyanin synthesis by P. aeruginosa under Ag NPs. This investigation presents novel clean production of five MNPs/MONPs with prominent advantages of being ecofriendly and cost-effective and having antipathogen properties.

Metal nanoparticles (MNPs) produced by green approaches have received global attention because of their physicochemical characteristics and their applications in the field of biotechnology. In recent years, the development of synthesizing NPs by plant extracts has become a major focus of researchers because of these NPs have low hazardous effect in the environment and low toxicity for the human body. Synthesized NPs from plants are not only more stable in terms of size and shape, also the yield of this method is higher than the other methods. Moreover, some of these MNPs have shown antimicrobial activity which is consistently confirmed in past few years. Plant extracts have been used as reducing agent and stabilizer of NPs in which we can reduce the toxicity in the environment as well as the human body only by not using chemical agents. Furthermore, the presence of some specific materials in plant extracts could be extremely helpful and effective for the human body; for instance, polyphenol, which may have antioxidant effects has the capability for capturing free radicals before they can react with other biomolecules and cause serious damages. In this article, we focused on of the most common plants which are regularly used to synthesize MNPs along with various methods for synthesizing MNPs from plant extracts.