目的评价金盏花茶配方的抗炎和抗氧化性能。材料和方法在这项研究中,将2克干燥万寿菊花瓣和100毫升(ml)蒸馏水的制剂进行使用白蛋白变性测定的抗炎测试和通过DPPH(2,2-二苯基-1-甲基-肼-水合物)测定的抗蛋白酶活性和抗氧化剂测试。使用SPSS版本22.0软件(IBMCorp.,Armonk,NY),任何小于0.05的p值被认为具有统计学意义。结果在10微升(μl)和20μl(p值=0.002和0.000)时,万寿菊提取物的抗炎和抗氧化活性最高。分别。在所有浓度下,抗炎活性均高于对照,而与较高浓度相比,较低浓度时的抗氧化活性较高。结论万寿菊花茶配方显示出比对照更好的抗炎和抗氧化活性,因此可作为潜在的治疗剂。
Aim To assess the anti-inflammatory and antioxidant properties of Calendula officinalis tea formulation. Materials and methods In this study, a formulation of 2 grams of dried marigold flower petals and 100 milliliters (ml) of distilled water was subjected to anti-inflammatory testing using albumin denaturation assay and anti-protease activity and antioxidant testing by DPPH (2,2-diphenyl-1-picryl-hydrazyl-hydrate) assay. An independent sample t-test was done to compare the anti-inflammatory and antioxidant potentials of marigold tea formulation and control using SPSS version 22.0 software (IBM Corp., Armonk, NY), and any p-value less than 0.05 was considered statistically significant. Results The highest anti-inflammatory and antioxidant activities of marigold extract were exhibited at 10 microliters (µl) and 20 µl (p-value = 0.002 and 0.000), respectively. The anti-inflammatory activity was higher than the control at all concentrations, whereas the antioxidant activity was higher at lower concentrations when compared to higher concentrations. Conclusion Marigold flower tea formulation exhibited better anti-inflammatory and antioxidant activities than the controls and therefore could be evaluated as a potential therapeutic agent.