long‐acting reversible contraception

  • 文章类型: Journal Article
    背景:2002年,在公共卫生护士和助产士获得处方激素避孕药的授权的同时,挪威政府向青少年推出了激素避孕药的报销计划。这项研究考察了增加可及性和公共资金对青少年使用激素避孕药具的影响。
    方法:挪威处方数据库,挪威统计局,和挪威公共卫生研究所作为本队列研究的数据来源。研究人群包括1989-1990年,1994-1995年和1999-2000年出生的174653名挪威妇女。我们通过从12岁到19岁的处方来检查激素避孕药的使用情况,并将首次连续使用的持续时间作为主要结果。统计分析采用SPSS卡方检验,生存分析,和Joinpoint回归分析,p值<0.05。
    结果:到19岁时,约75%的队列至少使用了一种激素方法。第一个处方的主要提供者是全科医生和公共卫生护士。仅含孕激素的药丸(POPs)的开始在整个队列中增加,而联合口服避孕药(COCs)的起子有所减少。长效可逆避孕药(LARCs)的使用自纳入报销计划(2015年)以来一直在增加。在LARC成为报销计划的一部分之后,大多数转换者从COC或POP作为开始方法转移到植入物。在整个队列中,从日历年开始到结束时连续使用激素避孕药的妇女人数显着增加,她们以相同的方法和切换方法后成为19岁。我们无法将少女分娩或人工流产(Joinpoint分析)下降趋势的变化与实施时间或从2002年开始激素避孕药报销的变化相关联。
    结论:主要是公共卫生护士和较小程度的助产士在获得处方COCs的授权后不久就成为重要的提供者。扩大偿还计划,以涵盖持久性有机污染物,补丁,阴道环,2006年的醋酸甲羟孕酮对增加长期首次使用者的比例影响较小。然而,2015年纳入LARCs显著增加了长期首次使用激素避孕药的比例.
    BACKGROUND: The Norwegian Government introduced in 2002 a reimbursement scheme for hormonal contraceptives to adolescents at the same time as public health nurses and midwives received authorization to prescribe hormonal contraceptives. This study examines the impact of increased accessibility and public funding on hormonal contraceptive use among adolescents.
    METHODS: The Norwegian Prescription Database, Statistics Norway, and Norwegian Institute of Public Health served as data sources for this cohort study. The study population comprised 174 653 Norwegian women born 1989-1990, 1994-1995, and 1999-2000. We examined use of hormonal contraceptives through dispensed prescriptions from age 12 through age 19 with duration of first continuous use as primary outcome. The statistical analyses were done in SPSS using chi-squared test, survival analysis, and Joinpoint regression analysis with p-values < 0.05.
    RESULTS: By age 19, ~75% of the cohorts had used at least one hormonal method. The main providers of the first prescription were general practitioners and public health nurses. Starters of progestogen-only pills (POPs) have increased across the cohorts, while starters of combined oral contraceptives (COCs) have decreased. The use of long-acting reversible contraceptives (LARCs) has increased since its inclusion in the reimbursement scheme (2015). Most switchers shifted from COCs or POPs as a start method to implants after LARCs became part of the reimbursement scheme. There has been a significant increase across the cohorts in the number of women who continuously used hormonal contraceptives from start to the end of the calendar year they became 19 years with the same method and after switching methods. We could not correlate changes in decreasing trends for teenage births or induced abortions (Joinpoint analysis) to time for implementation or changes in the reimbursement of hormonal contraceptives from 2002.
    CONCLUSIONS: Primarily public health nurses and to a lesser extent midwives became soon after they received authorization to prescribe COCs important providers. The expansion of the reimbursement scheme to cover POPs, patches, vaginal ring, and depot medroxyprogesterone acetate in 2006 had minor impact on increasing the proportion of long-term first-time users. However, the inclusion of LARCs in 2015 significantly increased the proportion of long-term first-time hormonal contraceptive users.
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  • 文章类型: Journal Article
    背景:仅使用孕激素的长效可逆避孕(LARC)可能是痤疮的危险因素。很少有研究主要集中在激素LARC对青少年和年轻人痤疮发展或恶化的影响。我们试图了解在这个青少年/年轻成人人群中插入激素LARC后痤疮的发生率和管理。
    方法:对从青少年医学LARC协作组织中前瞻性收集的质量改进(QI)数据进行了二次数据分析。受试者由参与研究地点的青少年医学诊所的临床医生进行评估。使用标准化记录仪器和量表记录痤疮严重程度。描述性统计被报告为分类变量的频率和百分比或连续变量的平均值和标准偏差(SD)。我们比较了痤疮恶化者的人口统计学和临床特征,使用分类变量的Cochran-Mantel-Haenszel卡方检验和连续变量的线性广义估计方程(GEE)回归来解释站点相互相关性。
    结果:在完成LARC插入的1319名受试者中,28.5%(376/1319)在使用仅孕激素的LARC后出现痤疮恶化。痤疮是LARC去除的一个促成因素,只有3%(40/1319),以及所有受试者中0.4%(5/1319)的移除的唯一原因。由于这是对前瞻性收集的QI数据的二次分析,这项研究的局限性包括痤疮严重程度的记录不完整或不准确.此外,我们的研究中排除了未进行随访/切除访视或仅在8周内进行随访/切除的LARC插入。这也可能会使结果产生偏差。
    结论:寻求仅使用孕激素的LARC的青少年和年轻人应该被告知在使用LARC期间发展成痤疮或现有痤疮恶化的可能性。然而,痤疮不是LARC停药的常见原因.
    BACKGROUND: The use of progestin-only long-acting reversible contraception (LARC) may be a risk factor for acne. Few studies have focused primarily on the effects of hormonal LARC on the development or exacerbation of acne in adolescents and young adults. We sought to understand the incidence and management of acne following hormonal LARC insertion in this adolescent/young adult population.
    METHODS: A secondary data analysis was conducted of prospectively collected quality improvement (QI) data from the Adolescent Medicine LARC Collaborative. Subjects were evaluated by clinicians in adolescent medicine clinics at participating study sites, and acne severity was documented using a standardized recording instrument and scale. Descriptive statistics were reported as frequencies and percentages for categorical variables or mean and standard deviation (SD) for continuous variables. We compared demographic and clinical characteristics by those who had worsening acne, accounting for site inter-correlation using Cochran-Mantel-Haenszel chi-square tests for categorical variables and linear generalized estimating equation (GEE) regression for continuous variables.
    RESULTS: Of 1319 subjects who completed LARC insertion, 28.5% (376/1319) experienced worsening acne following use of progestin-only LARC. Acne was a contributing factor to LARC removal in only 3% (40/1319), and the sole reason for removal in 0.4% (5/1319) of all subjects. As this was a secondary analysis of prospectively collected QI data, limitations of this study include incomplete or inaccurate documentation of acne severity. Moreover, LARC insertions without follow-up/removal visits or with only follow-up/removal within 8 weeks of insertion were excluded from our study, which may also bias results.
    CONCLUSIONS: Adolescents and young adults seeking progestin-only LARC should be counseled about the potential for developing acne or experiencing a worsening of existing acne during LARC use. However, acne was not a common reason for LARC discontinuation.
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  • 文章类型: Randomized Controlled Trial
    背景:高效长效可逆避孕(LARC)方法可降低意外怀孕率;但是,这些方法没有得到充分利用。LOWE试验干预提供了结构化的避孕咨询,导致LARC的摄取增加。LOWE研究的纵向随访通过调查12个月时的避孕药具使用,重点是继续使用LARC,评估了干预措施的长期影响。
    方法:在整群随机LOWE试验中,流产,青春,和孕产妇保健诊所随机提供结构化避孕咨询(干预)或标准避孕咨询(对照).干预包括一个关于避孕方法的教育视频,医疗保健提供者提出的关键问题,一个分层的有效性图表和一盒避孕模型。年龄≥18岁的女性,在接下来的6个月内性活跃或计划性活跃,可以参与研究。我们在三岁时评估了自我报告的避孕药具使用情况,6个月和12个月。对避孕药具的选择和切换进行描述性统计分析。使用混合逻辑回归分析12个月时的避孕药具使用和持续使用LARC,临床包括作为随机效应。对缺失数据进行了估算值的分析,以测试结果的稳健性。
    结果:总体而言,12个月时,与对照组相比,干预组女性更有可能使用LARC方法(aOR1.90,95%CI:1.31~2.76),而使用短效可逆避孕(SARC)方法(aOR0.66,95%CI:0.46~0.93)的可能性较小.接受堕胎咨询的妇女(aOR2.97,95%CI:1.36-6.75)和青年诊所(aOR1.81,95%CI:1.08-3.03)更有可能使用LARC方法,而在孕产妇保健诊所中没有发现显着差异(aOR1.84,95%CI:0.96-3.66)。在启动LARC的女性中,12个月时的延续率在研究组之间没有差异(63.9%vs.63.7%)。停止避孕的最常见原因是希望怀孕,其次是不规则出血,和情绪变化。
    结论:LOWE试验干预在12个月时也导致LARC使用增加。需要进一步研究如何维持LARC使用的策略。
    BACKGROUND: Highly effective long-acting reversible contraceptive (LARC) methods reduce unintended pregnancy rates; however, these methods are underutilized. The LOWE trial intervention provided structured contraceptive counseling resulting in increased uptake of LARC. This longitudinal follow up of the LOWE study assessed the long-term impact of the intervention by investigating the contraceptive use at 12 months with a focus on continued use of LARC.
    METHODS: In the cluster randomized LOWE trial, abortion, youth, and maternal health clinics were randomized to provide either structured contraceptive counseling (intervention) or standard contraceptive counseling (control). The intervention consisted of an educational video on contraceptive methods, key questions asked by the health care provider, a tiered effectiveness chart and a box of contraceptive models. Women ≥ age 18, who were sexually active or planned to be in the upcoming 6 months, could participate in the study. We assessed self-reported contraceptive use at three, six and 12 months. Contraceptive choice and switches were analyzed with descriptive statistics. Contraceptive use at 12 months and continued use of LARC were analyzed using mixed logistic regressions, with clinic included as a random effect. Analysis with imputed values were performed for missing data to test the robustness of results.
    RESULTS: Overall, at 12 months, women in the intervention group were more likely to be using a LARC method (aOR 1.90, 95% CI: 1.31-2.76) and less likely to be using a short-acting reversible contraceptive (SARC) method (aOR 0.66, 95% CI: 0.46-0.93) compared to the control group. Women counseled at abortion (aOR 2.97, 95% CI: 1.36-6.75) and youth clinics (aOR 1.81, 95% CI: 1.08-3.03) were more likely to be using a LARC method, while no significant difference was seen in maternal health clinics (aOR 1.84, 95% CI: 0.96-3.66). Among women initiating LARC, continuation rates at 12 months did not differ between study groups (63.9% vs. 63.7%). The most common reasons for contraceptive discontinuation were wish for pregnancy, followed by irregular bleeding, and mood changes.
    CONCLUSIONS: The LOWE trial intervention resulted in increased LARC use also at 12 months. Strategies on how to sustain LARC use needs to be further investigated.
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  • 文章类型: Journal Article
    目的:互联网是健康信息的重要来源,然而,有关长效可逆避孕的信息质量(LARC,在线发现的宫内节育器(IUD)和避孕植入物)在很大程度上是未知的。
    方法:对Google搜索中返回的网页进行范围审查。如果结果是用英语写的并且包含有关LARC的信息,则包括结果的前三页。使用DISCERN健康信息工具对结果进行了严格审查和评估。
    结果:在778个结果中,306页符合资格标准。虽然大多数网页提供了有关LARC的关键信息,包括体内的位置,好处,副作用和风险,提供的信息差异很大。只有一半提到疗效,许多网页没有提供有关插入和移除费用的信息,如何以及在哪里访问设备或它们如何工作。尽管超过四分之三的网页提到了副作用,这些内容的深度和特殊性差异很大,并且在不同的网页上经常相互矛盾。
    结论:大多数网页向消费者提供了医学上准确的信息;然而,许多人没有包括关键信息,如成本或它们是如何工作的。不同网页的副作用描述不同,这可能会阻碍明智的决策。所以呢?:大多数人在拜访医疗保健提供者之前就决定他们可能喜欢使用哪种避孕方法,大多数人会从互联网上获得这些信息。提供全面、关于宫内节育器和避孕植入物的医学准确和一致的信息对于支持知情决策至关重要.
    OBJECTIVE: The internet is an important source of health information, however, the quality of information about long-acting reversible contraception (LARC, including intrauterine devices (IUDs) and contraceptive implants) found online is largely unknown.
    METHODS: A scoping review of webpages returned in a Google search was conducted. The first three pages of results were included if they were written in English and contained information about LARC. Results were critically reviewed and assessed using the DISCERN quality of health information tool.
    RESULTS: Of 778 results, 306 pages met the eligibility criteria. While most webpages provided key information about LARC, including location in the body, benefits, side effects and risks, the information provided varied considerably. Only half mentioned efficacy and many webpages did not provide information about the cost of insertion and removal, how and where to access the devices or how they work. Despite side effects being mentioned in more than three-quarters of webpages, the depth and specificity of these varied considerably and were often contradictory across different webpages.
    CONCLUSIONS: Most webpages provided medically accurate information to consumers; however, many did not include key information such as cost or how they work. Descriptions of side effects varied between webpages, and this may inhibit informed decision-making. SO WHAT?: Most people make decisions about what contraceptive method they might like to use before visiting a health care provider, and most will get this information from the internet. Providing comprehensive, medically accurate and consistent information about both IUDs and contraceptive implants is vital to support informed decision-making.
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  • 文章类型: Journal Article
    目的:确定在线教育干预的组成部分,以提高对,和吸收,来自文化和语言不同背景的妇女的长效可逆避孕(CALD)。
    目标:来自文化和语言多样性(CALD)背景的女性比本地出生的女性有更高的意外怀孕率,并且不太可能使用长效可逆避孕药(LARCs)。在减少意外怀孕方面非常有效。在来自CALD背景的女性中增加LARC的摄取可能会减轻这个高危人群中意外怀孕的负担。在线教育干预已被证明可以有效地增加年轻女性对LARC的偏爱和吸收。我们的目的是描述来自CALD背景的女性认为什么是在线教育干预的潜在有效组成部分,以增加偏好,和吸收,长效可逆避孕。
    方法:这项定性研究涉及对六名来自中国人的澳大利亚英语女性进行半结构化访谈,印度人,和中东文化背景。女性是通过有针对性的Facebook广告招募的。使用Braun和Clarke主题分析对数据进行分析。
    结果:共有18名参与者接受了访谈。我们已经证明了为文化价值观量身定制信息的重要性,翻译视频,将目标受众扩大到男性和女性,并使用特定的社交媒体平台。对于所有的女人来说,视频需要强调避孕方法的隐蔽性,同时说明成本和访问方法。对于印度女性来说,该视频需要强调LARC方法对印度妇女月经期的影响,并包括妇女健康的基本信息。对于中东妇女,该视频应明确说明LARC不等同于堕胎,并强调自然避孕方法的低效率。对于中国女性来说,该视频应该解决荷尔蒙损害身体的误解。关于视频的交付,它应该由来自同一文化的女医生翻译和交付。对于中国女性来说,该视频应包括来自同一文化的女性分享轶事,并使用微信和中文学校作为传播平台。对于中东和印度妇女,应使用政府网站进行传播。该视频应提供给生殖规划过程中的所有决策者,包括中东妇女的男性伴侣,中国女性的父母和同龄人,对印度女性来说,男性伴侣,家庭,和社区领袖。
    结论:可以对有关LARCs的在线教育视频进行广泛的文化调整,以提高LARCs的吸收,从而减轻来自CALD的女性意外怀孕的负担。所以呢?:我们的发现将用于修改有关LARC的在线教育视频,以使其在文化上适合来自CALD背景的女性。
    OBJECTIVE: To identify components of an online education intervention to improve preference for, and uptake of, long-acting reversible contraception in women from culturally and linguistically diverse backgrounds (CALD).
    OBJECTIVE: Women from culturally and linguistically diverse (CALD) backgrounds have greater rates of unintended pregnancies than those born locally and are less likely to use long-acting reversible contraceptives (LARCs), which are highly effective at reducing unintended pregnancy. Increasing the uptake of LARC in women from CALD backgrounds may reduce the burden of unintended pregnancy in this high-risk group. An online education intervention has been shown to be effective at increasing preference for and uptake of LARC in young women. We aimed to describe what women from CALD backgrounds thought were the potentially effective components of an online education intervention to increase preference for, and uptake of, long-acting reversible contraception.
    METHODS: This qualitative study involved semi-structured interviews with six Australian English-speaking women from each of Chinese, Indian, and Middle Eastern cultural backgrounds. Women were recruited through targeted Facebook advertising. Data were analysed using Braun and Clarke thematic analysis.
    RESULTS: A total of 18 participants were interviewed. We have demonstrated the importance of messages tailored to cultural values, translating the video, widening the target audience to both men and women and using specific social media platforms. For all women, the video needs to highlight the covertness of contraceptive methods, alongside stating cost and approach to access. For Indian women, the video needs to highlight the effect of LARC methods on the menstrual period for Indian women and include basic information on women\'s health. For Middle Eastern women the video should be explicit about LARC not equating to abortion and emphasise the low efficacy of natural contraceptive methods. For Chinese women, the video should address the misconception that hormones damage the body. Regarding delivery of the video, it should be translated and delivered by a female doctor from the same culture. For Chinese women, the video should include women from the same culture sharing anecdotes and use WeChat and Chinese schools as a platform for dissemination. For Middle Eastern and Indian women government websites should be used for dissemination. The video should be made available to all decision-makers in the reproductive planning process including male partners of Middle Eastern women, parents and peers of Chinese women, and for Indian women the male partner, family, and community leaders.
    CONCLUSIONS: There is a wide range of cultural adaptations that can be made to the online education videos about LARCs to improve uptake of LARCs and hence reduce the burden of unintended pregnancy in women from CALD grounds. SO WHAT?: Our findings will be used to modify an online education video about LARCs so that it is culturally appropriate for women from CALD backgrounds.
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