在过去的几十年里,由于抗生素的猖獗使用,真菌性鼻窦炎(FRS)有所增加。类固醇,免疫抑制药物,艾滋病毒和不受控制的糖尿病发病率增加。当前的研究回顾了类型,临床表现,微生物学,印度北部三级护理中心与FRS相关的组织病理学和结局。方法回顾性分析3年FRS患者的临床和随访记录。审查的数据包括临床检查,眼科简介,合并症,免疫状态,放射学调查,术中和组织病理学发现,治疗和随访记录。此外,我们对回顾的数据进行了描述性分析.结果该研究包括30例FRS患者(16例男性,14女)。在此,77%的病例是过敏性FRS,而真菌球,慢性侵入性,慢性肉芽肿和急性侵袭性FRS占3%,10%,3%和7%的病例,分别。最常见的非侵入性形式是鼻塞,鼻腔分泌物,失足和息肉,而它是面部疼痛和头痛的侵袭性品种。在通过内窥镜鼻窦手术进行适当的医疗和手术管理后,非侵袭性和侵袭性真菌性鼻窦炎的复发率分别为16.6%和20.8%,分别。在至少一年的随访中,死亡率为零。结论FRS的非侵入性形式常见,病程相对较轻。早期医学和外科干预以及潜在合并症的管理是管理侵入性FRS的关键因素。手术后密切随访对于及时发现和管理复发也是必要的。
Introduction Fungal rhinosinusitis (FRS) has increased over the past few decades due to the rampant use of antibiotics, steroids, immunosuppressive drugs, increased incidence of HIV and uncontrolled diabetes. The current study reviews the types, clinical presentation, microbiology, histopathology and outcomes related to FRS in a tertiary care center in North India. Methods We retrospectively reviewed the clinical and follow-up records of patients diagnosed with FRS over three years. The data reviewed included clinical workup, ophthalmological profile, comorbidities, immunological status, radiological investigations, intraoperative and histopathological findings, treatment and follow-up records. In addition, we performed a descriptive analysis of the reviewed data. Results The study consisted of 30 FRS patients (16 male, 14 female). In that, 77% of cases were of allergic FRS, while fungal ball, chronic invasive, chronic granulomatous and acute invasive FRS represented 3%, 10%, 3% and 7% cases, respectively. The most common presentation in non-invasive forms was nasal obstruction, nasal discharge, hyposmia and polyposis, while it was facial pain and headache in the invasive varieties. After appropriate medical and surgical management through endoscopic sinus surgery, the recurrence rate in non-invasive and invasive fungal sinusitis was 16.6% and 20.8%, respectively. There was nil mortality at a minimum of one year of follow-up. Conclusion The non-invasive forms of FRS are common and have a relatively mild course. Early medical and surgical intervention and management of the underlying comorbidities are the key factors in managing invasive FRS. Close follow-up after surgery is also necessary for the timely detection and management of recurrences.