精神病性障碍对心理社会功能的影响不同。然而,很少有研究直接比较精神分裂症之间的心理社会功能及其决定因素,分裂情感障碍(SAD),双相情感障碍(BD),和具有精神病性特征的重度抑郁症(精神病性MDD)。
我们比较了独立生活的比率,employment,婚姻,在芬兰有大量的全国精神病患者样本中,这些诊断组之间有孩子。
芬兰SUPER研究中18至65岁的参与者(N=9148)的横断面子研究,在全国范围内从健康和社会护理机构招募,并提供广告。精神病诊断,发病年龄,和住院是从医疗登记册收集。对参与者进行了心理社会功能访谈。发病年龄的关联,住院治疗,性别,使用逻辑回归模型分析了具有社会心理功能的教育。
参与者,13.8%受雇或学习,72.0%独立生活,32.5%有孩子。总的来说,BD与最好的,SAD和精神病性MDD,中间,和精神社会功能最差的精神分裂症。在独立生活中发现了最大的差异(BD与BD的OR4.06精神分裂症)。在多变量模型中,性别和住院人数预测就业,婚姻,在所有诊断类别中独立生活,以及某些诊断类别的发病年龄。
精神病患者的功能水平和心理社会结果明显不同,尤其是独立生活。精神分裂症的结局最差,BD最好。在所有的精神疾病中,女性性别和终生住院人数与婚姻有很强的独立关联,employment,独立生活。
Psychotic disorders differ in their impact on psychosocial functioning. However, few studies have directly compared psychosocial functioning and its determinants between schizophrenia, schizoaffective disorder (SAD), bipolar disorder (BD), and major depressive disorder with psychotic features (psychotic MDD).
We compared rates of independent living, employment, marriage, and having children between these diagnostic groups in a large national sample of participants with psychotic disorders in Finland.
A cross-sectional substudy of participants (N = 9148) aged 18 to 65 years in the Finnish SUPER study, recruited nationwide from health- and social care settings and with advertisements. Psychosis diagnoses, age of onset, and hospitalizations were collected from healthcare registers. Participants were interviewed for psychosocial functioning. Associations of age of onset, hospitalizations, gender, and education with psychosocial functioning were analyzed using logistic regression models.
Of participants, 13.8% were employed or studying, 72.0% living independently and 32.5% had children. Overall, BD was associated with best, SAD and psychotic MDD with intermediate, and schizophrenia with worst level of psychosocial functioning. Greatest differences were found in independent living (OR 4.06 for BD vs. schizophrenia). In multivariate models, gender and number of hospitalizations predicted employment, marriage, and independent living in all diagnostic categories, and age of onset in some diagnostic categories.
Level of functioning and psychosocial outcomes differed markedly between psychotic disorders, particularly in independent living. Outcomes were worst for schizophrenia and best for BD. Across all psychotic disorders, female gender and lifetime number of hospitalizations had strong independent associations with marriage, employment, and independent living.