Lemierre\'s syndrome (LS) is a rare and severe complication primarily associated with the bacteria Fusobacterium necrophorum and characterized by an oropharyngeal infection leading to bacteremia and septic thrombophlebitis. We present a case of an 89-year-old patient with a history of hypertension who initially presented with type B influenza infection and neck pain. She subsequently developed a neck abscess with thrombosis of the internal jugular vein. We believe this to be the first reported case in the literature of LS secondary to Streptococcus intermedius presenting after infection with type B influenza. As more atypical LS cases emerge, it is becoming increasingly clear that this condition can manifest in a number of ways. This unique case highlights the importance of considering LS as a differential diagnosis for patients of all ages presenting with neck pain and Streptococcus intermedius infection.

A male child with a history of sinusitis presented to the emergency medicine department with a high fever, neck swelling, headache, vomiting, and double vision. He was diagnosed with retropharyngeal abscess (RPA) with bilateral internal jugular vein (IJV) and cerebral venous thromboses. The child was treated promptly and transferred to a specialty center, where the abscess was drained. However, he developed papilledema and septic embolism, leading to pulmonary embolism and cerebral abscesses. The child was an inpatient for six weeks and had outpatient treatment for three months. He developed exotropia due to bilateral sixth cranial nerve palsy. This existed even at the 24-month follow-up. This case report highlights the rare complications and morbidity from the retropharyngeal abscess. It also emphasizes the early diagnosis and management options in a busy emergency medicine department.