背景:几十年来,认为选择性手术和皮肤手术应该推迟6-12个月,或者最近服用了异维甲酸,已被广泛接受。然而,最近的一些研究表明,在这方面需要改变。
方法:这里,我们通过在PubMed上搜索来审查这方面的现有数据,谷歌学者,还有Scopus.所有相关论文均以英文发表,直到十月,2022年,我们可以访问他们的全文,包括在内。
结果:我们发现了整形外科医生提出的一些建议,皮肤科医生,耳鼻喉科外科医生,眼科医生,骨科医生,和牙医关于患者手术干预的正确时机,或最近服用异维A酸,并试图总结它们,为临床医生提供实用指南。
结论:医师可以与患者讨论在全身异维A酸治疗的背景下伤口愈合异常的已知风险,并建议,如果可能,外科手术被推迟,直到类维生素A的活性有时间消退。对于深色皮肤照型的患者,遵循更严格的指南更为重要。
BACKGROUND: For decades, the notion that elective surgeries and cutaneous procedures should be postponed for 6-12 months in patients on, or recently administered with isotretinoin, has been widely accepted. However, some recent studies showed the need for a change in this regard.
METHODS: Here, we reviewed the existing data in this regard through searching on PubMed, Google Scholar, and Scopus. All of the relevant papers published in English, until October, 2022, which we could access to their full-texts, were included.
RESULTS: We found some recommendations made by plastic surgeons, dermatologists, ENT surgeons, ophthalmologists, orthopedic surgeons, and dentists regarding the correct timing of procedural interventions in patients on, or recently administered with isotretinoin and tried to summarize them to provide a practical guide for clinicians.
CONCLUSIONS: Physicians may discuss with patients regarding the known risk of abnormal wound healing in the setting of systemic isotretinoin treatment and suggest that, when possible, surgical procedures be postponed until the activity of the retinoids has time to subside. It is even more important regarding patients with darker skin phototypes to follow an even more strict guideline.