背景:长型COVID综合征包括在感染COVID-19期间或之后出现的各种体征和症状,这些体征和症状可能会影响身体能力。然而,缺乏研究调查长COVID综合征对COVID-19感染后运动能力的影响。该研究的目的是评估和比较长期COVID患者和在北欧步行运动治疗期间未发展为非长期COVID患者的乳酸浓度和生活质量(QoL)。
方法:29名患者(25.5±7.1岁)参加了一项非随机对照试验,分为两组:长COVID组(n=16)和非长COVID对照组(n=13)。如果患者在进行日常活动时感到疲劳或疲倦,并且在剧烈的身体或精神活动后症状恶化,则被证实患有长型COVID综合征。所有参与者都接受了为期12周的北欧步行计划。测量运动后的乳酸浓度和所有会话期间的距离。前和长期北欧步行计划,修正的疲劳冲击量表(MFIS),简短表格36健康调查(SF-36),和EUROQoL-5D(EQ-ED)用于评估疲劳和生活质量,分别。
结果:组间存在乳酸浓度效应(F=5.604;p=0.024)。然而,该会话没有显着影响(F=3.521;p=0.121),没有组×会话的相互作用(F=1.345;p=0.414)。组主要效应(F=23.088;p<0.001),时间效应(F=6.625;p=0.026),并记录了SF-36量表上的组×时间(F=4.632;p=0.002)相互作用。此外,有显著的群体主效应(F=38.372;p<0.001),时间效应(F=12.424;p=0.005),和EQ-5D的组×时间相互作用(F=4.340;p=0.014)。然而,在MFIS量表上,仅有显着的组主效应(F=26.235;p<0.001),对时间(F=2.265;p=0.160)和组×时间(F=1.584;p=0.234)的交互作用没有影响。
结论:在北欧步行计划的12周内,Long-COVID组的乳酸浓度高于对照组。根据MFIS量表,Long-COVID组的疲劳相对于对照组有所下降,以及改善有氧运动治疗后的生活质量。
BACKGROUND: Long-COVID syndrome comprises a variety of signs and symptoms that develop during or after infection with COVID-19 which may affect the physical capabilities. However, there is a lack of studies investigating the effects of Long-COVID syndrome in sport capabilities after suffering from COVID-19 infection. The purpose of the study was to evaluate and compare lactate concentration and quality of life (QoL) in patients with Long-COVID with those who have not developed non-Long-COVID during Nordic walking exercise therapy.
METHODS: Twenty-nine patients (25.5 ± 7.1 years) took part in a non-randomized controlled trial, divided into two groups: a Long-COVID group (n = 16) and a non-Long-COVID control (n = 13). Patients were confirmed as having Long-COVID syndrome if they experienced fatigue or tiredness when performing daily activities and worsening of symptoms after vigorous physical or mental activity. All participants underwent a 12-week Nordic Walking program. Lactate concentration after exercise and distance covered during all sessions were measured. Pre- and Long-Nordic Walking program, the Modified Fatigue Impact Scale (MFIS), the Short Form 36 Health Survey (SF-36), and EURO QoL-5D (EQ-ED) were administered to assess fatigue and quality of life, respectively.
RESULTS: There was a lactate concentration effect between groups (F = 5.604; p = 0.024). However, there was no significant effect as a result of the session (F = 3.521; p = 0.121) with no interaction of group × session (F = 1.345; p = 0.414). The group main effect (F = 23.088; p < 0.001), time effect (F = 6.625; p = 0.026), and group × time (F = 4.632; p = 0.002) interaction on the SF-36 scale were noted. Also, there were a significant group main effect (F = 38.372; p < 0.001), time effect (F = 12.424; p = 0.005), and group × time interaction (F = 4.340; p = 0.014) on EQ-5D. However, there was only a significant group main effect (F = 26.235; p < 0.001) with no effect on time (F = 2.265; p = 0.160) and group × time (F = 1.584; p = 0.234) interaction on the MFIS scale.
CONCLUSIONS: The Long-COVID group showed higher lactate concentration compared with the control group during the 12 weeks of the Nordic Walking program. The Long-COVID group presented a decrease in fatigue with respect to the control group according to the MFIS scale, as well as improvement in quality of life after aerobic exercise therapy.