多分析物检测和模拟判别因其在环境中的广泛应用而成为极具价值的前沿领域,medical,临床和工业分析。如今,研究人员绞尽脑汁研究如何开发优秀的多分析物化学传感器,这些传感器在设计高效荧光传感材料和构建高通量检测方法方面提出了巨大挑战。在本文中,我们提出了一种利用双发射荧光检测平台作为分子实验室的新策略,源于二alicyl醛配位的杂化H2Qj3/Tb基tb敏化耦合激发态分子内质子转移效应。使用统计分析(PCA和HCA)来感测三个荧光通道(431、543和583nm)的信号,我们展示了这种复杂的化学传感器,具有三种物质的多分析物检测(溶剂,阴离子和阳离子)和类似物的模式识别。因此,H2Qj3/Tb对每一组物种都有很好的分子实验室特征,导致更容易识别许多关键分析物(例如,H2O,NO2-和Fe3)和类似物的区分。此外,它也被证明能够为分析物提供可靠的含量测定,特别是NO2-(LOD=0.37μM),以及对混合类似物的区分。易于实施的制备程序和数据分析技术的结合使这项工作不仅有望设计类似的基于镧系元素的材料,而且还实现了针对各种潜在应用的更高效的多分析物感测系统。
Multianalyte detection and analogue discrimination are extremely valuable frontier areas for their wide applications in environmental, medical, clinical and industrial analyses. Nowadays, researchers rack their brains on how to develop excellent multianalyte chemosensors that have presented huge challenges in designing high-efficient fluorescent sensing materials and constructing high-throughput detection methods. In this paper, we propose a novel strategy to utilize the dual-emission fluorescent detection platform as a lab-on-a-molecule, arising from the disalicylaldehyde-coordinated hybrid H2Qj3/Tb based terbium sensibilization coupled excited-state intramolecular proton transfer effects. Using the statistical analysis (PCA and HCA) for sensing signals of three fluorescence channels (431, 543 and 583 nm), we demonstrate this elaborate chemosensor with multianalyte detection of three species (solvents, anions and cations) and pattern discrimination of analogues. As a result, the H2Qj3/Tb shows great lab-on-a-molecule characters for each set of species, resulting in the easier identification of many critical analytes (e.g., H2O, NO2- and Fe3+) and discrimination of analogues. In addition, it is also proven to be able to provide reliable content determination for an analyte, especially the NO2- (LOD = 0.37 μM), and discrimination for mixed analogues. A combination of easy-to-implement preparation procedure and data analysis technique makes this work promising for not only designing similar lanthanide-based materials but also realizing more high-efficient multianalyte sensing systems towards various potential applications.