■从开始到2023年,在WebofScienceCoreCollection(WOSCC)中搜索了有关PD和铁沉积的相关研究。VOSviewer,CiteSpace,RStudio,和ScimagoGraphica被用作文献计量分析工具,以生成有关作者之间合作的网络图,国家,和机构,并可视化共同引用的参考文献和关键词的共同出现和趋势。
■共检索到160篇与PD和铁中毒有关的原创文章和评论,由来自162个机构的958位作者制作。DevosDavid是最多产的作家,9条中国和墨尔本大学在出版物数量上处于领先地位,有84和12种出版物,分别。当前的热门话题集中在通过深入了解特定的分子机制来挖掘基于铁性凋亡治疗PD的潜在新靶标。包括铁代谢紊乱,脂质过氧化,和不平衡的抗氧化剂调节。旨在通过靶向铁死亡治疗PD的临床研究仍处于初步阶段。
■在过去十年中,相关领域的文献显示了持续增长。目前的研究表明作者之间积极合作,国家,和机构。近年来,基于铁性凋亡的PD的发病机制和治疗研究一直是该领域的重要课题。表明铁凋亡靶向治疗是阻止PD进展的潜在方法。
UNASSIGNED: Related studies on PD and ferroptosis were searched in Web of Science Core Collection (WOSCC) from inception to 2023. VOSviewer, CiteSpace, RStudio, and Scimago Graphica were employed as bibliometric analysis tools to generate network maps about the collaborations between authors, countries, and institutions and to visualize the co-occurrence and trends of co-cited references and keywords.
UNASSIGNED: A total of 160 original articles and reviews related to PD and ferroptosis were retrieved, produced by from 958 authors from 162 institutions. Devos David was the most prolific author, with 9 articles. China and the University of Melbourne had leading positions in publication volume with 84 and 12 publications, respectively. Current hot topics focus on excavating potential new targets for treating PD based on ferroptosis by gaining insight into specific molecular mechanisms, including iron metabolism disorders, lipid peroxidation, and imbalanced antioxidant regulation. Clinical studies aimed at treating PD by targeting ferroptosis remain in their preliminary stages.
UNASSIGNED: A continued increase was shown in the literature within the related field over the past decade. The current study suggested active collaborations among authors, countries, and institutions. Research into the pathogenesis and treatment of PD based on ferroptosis has remained a prominent topic in the field in recent years, indicating that ferroptosis-targeted therapy is a potential approach to halting the progression of PD.