目的:Duane回缩综合征(DRS)是一种先天性综合征,其特征是内收和/或外展眼球运动受限,内收时睑裂狭窄,可能包括地球仪收回,向上或向下拍摄。几个系统性异常,综合症,和额外的眼部发现可以伴随DRS。这项研究是对DRS患者眼部表现的评估。
方法:对1995年至2016年随访的632例DRS患者的记录进行回顾性分析。随访少于6个月的患者和有眼/颅外伤或损伤史的患者不包括在研究中。在对患者进行检查之前,获得了详细的回忆。病历的细节,包括其他系统性疾病,被记录下来。
结果:随访时间平均45个月(min-max:6-128个月)。有255名男性和377名女性患者。共有34例患者(5.4%)有额外的眼部异常。与DRS相关的最常见的眼部病变是先天性上睑下垂(n=6,0.94%)和虹膜缺损(n=4,0.63%)。
结论:观察到大多数DRS病例是孤立的。然而,各种眼部和全身异常和综合征与DRS相关。特别是,多见于DRS时,可能会发现综合征.因此,在DRS患者中,完整的眼部检查和回忆至关重要。
OBJECTIVE: Duane retraction syndrome (DRS) is a congenital syndrome characterized by limitation in adduction and/or abduction eye movements and narrowing of the palpebral fissure in adduction, and may include globe retraction, upshoot or downshoot. Several systemic abnormalities, syndromes, and additional ocular findings can accompany DRS. This study is an evaluation of eye findings in patients with DRS.
METHODS: The records of 632 patients with DRS who were followed up between 1995 and 2016 were reviewed retrospectively. Patients with a follow-up of less than 6 months and patients with a history of eye/cranial trauma or injury were not included in the study. Before the patients were examined, a detailed anamnesis was obtained. Details of the medical records, including additional systemic diseases, were recorded.
RESULTS: The average of follow-up time was 45 months (min-max: 6-128 months). There were 255 male and 377 female patients. A total of 34 patients (5.4%) had additional ocular abnormalities. The most frequently observed ocular pathologies associated with DRS were congenital ptosis (n=6, 0.94%) and coloboma of the iris (n=4, 0.63%).
CONCLUSIONS: Most cases of DRS are observed as isolated. However, various ocular and systemic abnormalities and syndromes are associated with DRS. In particular, synkinetic syndromes may frequently be seen alongside DRS. Therefore, a complete ocular examination and anamnesis are crucial in cases with DRS.