颅内软骨瘤是一种罕见的良性肿瘤,通常在成年后发病。颅底是最常见的发生部位,尽管,很少,肿瘤可出现在大脑镰刀处或硬脑膜凸处。通过影像学将这些病变与脑膜瘤区分开通常很困难。
临床病例介绍和现有文献综述。
我们报告了一例25岁男性患者,在首次全身性癫痫发作后发现右额叶有脑膜附着的巨大凸面软骨瘤。根据脑膜瘤的推定诊断,通过矢状面旁开颅手术完全切除了肿瘤.术后MRI证实肿瘤完整切除。组织病理学分析显示存在软骨瘤。
颅内软骨瘤是罕见的,其基于神经影像学的术前诊断是困难的。在年轻患者和骨骼疾病患者中,应考虑软骨瘤的鉴别诊断。在有症状的患者中,手术切除是明智的。在大多数情况下,完全切除肿瘤是可能的,并导致完全恢复。当这一发现仅仅是老年患者的偶然发现时,警惕的等待方法是可以接受的,鉴于病变的良性和缓慢生长的性质。
Intracranial chondroma is a rare and benign tumor with usual onset in young adulthood. The skull base is the most common site of occurrence although, less often, the tumors can appear at the falx cerebri or at the dural convexity. The differentiation of these lesions from meningiomas through imaging is generally difficult.
Clinical case presentation and review of the current literature.
We report a case of a 25-year-old male patient with a giant convexity chondroma with meningeal attachment in the right frontal lobe that was detected after a first generalized seizure. Based on the putative diagnosis of meningioma, the tumor was completely resected via an osteoplastic parasagittal craniotomy. The postoperative MRI confirmed the complete tumor resection. Histopathological analysis revealed the presence of a chondroma.
Intracranial chondromas are a rarity and their preoperative diagnosis based on neuroimaging is difficult. In young patients and those with skeletal disease, the differential diagnosis of a chondroma should be considered. In symptomatic patients, operative resection is sensible. In most cases total removal of the tumor is possible and leads to full recovery. When the finding is merely incidental in older patients, a watchful waiting approach is acceptable, given the benign and slow-growing nature of the lesion.