intracranial chondroma

颅内软骨瘤
  • 文章类型: Journal Article
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  • 文章类型: Case Reports
    颅内脑膜凸性软骨瘤是一种罕见的良性病变,假设源于胚胎起源的残余软骨细胞前体。鉴于类似的基于硬脑膜的附着和钙化模式,该病变通常伪装成脑膜瘤。我们描述了一名26岁女性偶然发现的凸性脑膜软骨瘤的病例,最初推测是脑膜瘤.在这种情况下,我们分享我们的诊断和手术干预和结果,并讨论该病变的独特病理发现,将其与类似的病变区分开来。就作者所知,文献中的凸脑膜软骨瘤少于20例;因此,我们还对这种罕见病理的相关文献进行了简要回顾.
    Intracranial meningeal convexity chondroma is a rare benign lesion hypothesized to stem from remnant chondrocyte precursors of embryonic origin. This lesion often masquerades as meningioma given the similar dural-based attachment and pattern of calcification. We describe the case of a 26-year-old female with incidentally discovered convexity meningeal chondroma, originally presumed to be a meningioma. In this case, we share our diagnostic and operative intervention and outcome and discuss the unique pathologic findings in this lesion that differentiate it from similar appearing lesions. To the authors\' knowledge, there are fewer than 20 cases of convexity meningeal chondroma in the literature; thus, we also provide a brief review of the literature regarding this rare pathology.
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  • 文章类型: Case Reports
    Intracranial chondromas arising from the convexity with dural attachments are extremely rare tumors with scarce reports in the literature. They have atypical radiological findings that can often preclude the preoperative diagnosis. Complete resection is treatment with a good prognosis.
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  • 文章类型: Case Reports
    软骨瘤是成熟透明软骨的良性肿瘤,常见于长骨中,很少在身体其他部位被诊断出来。这里,我们介绍了一名年轻患者,其明确诊断为轴内颅内软骨瘤,并且没有硬脑膜连接。患者的症状是头痛和视力受损。脑磁共振成像(MRI)显示矢状旁脑肿块的巨大增强。通过免疫组织化学证实了诊断,S100呈阳性。
    Chondroma is a benign tumor of mature hyaline cartilage that is often found in the long bones and may be rarely diagnosed in other parts of the body. Here, we present a young patient with the definitive diagnosis of intra-axial intracranial chondroma and without dural connection. The presenting symptoms of the patient were headache and impaired vision. The brain magnetic resonance imaging (MRI) revealed a huge enhancing parasagittal brain mass. The diagnosis was confirmed by immunohistochemistry, which was positive for S100.
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  • 文章类型: Case Reports
    Intracranial chondromas are extremely rare, benign slow-growing cartilaginous tumors mostly originating from embryonic rests at sphenoethmoidal region and sometimes can originate from the falx, convexity dura, the tentorium, the choroid plexus, or the brain parenchyma. In this article, we present a 22-year-old woman with a chondroma of dural origin. The clinical, radiological, and histopathological findings along with the operative findings and postoperative course are described as well as the pertinent literature regarding intracranial chondromas is reviewed.
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  • 文章类型: Case Reports
    颅内软骨瘤是一种罕见的良性肿瘤,通常在成年后发病。颅底是最常见的发生部位,尽管,很少,肿瘤可出现在大脑镰刀处或硬脑膜凸处。通过影像学将这些病变与脑膜瘤区分开通常很困难。
    临床病例介绍和现有文献综述。
    我们报告了一例25岁男性患者,在首次全身性癫痫发作后发现右额叶有脑膜附着的巨大凸面软骨瘤。根据脑膜瘤的推定诊断,通过矢状面旁开颅手术完全切除了肿瘤.术后MRI证实肿瘤完整切除。组织病理学分析显示存在软骨瘤。
    颅内软骨瘤是罕见的,其基于神经影像学的术前诊断是困难的。在年轻患者和骨骼疾病患者中,应考虑软骨瘤的鉴别诊断。在有症状的患者中,手术切除是明智的。在大多数情况下,完全切除肿瘤是可能的,并导致完全恢复。当这一发现仅仅是老年患者的偶然发现时,警惕的等待方法是可以接受的,鉴于病变的良性和缓慢生长的性质。
    Intracranial chondroma is a rare and benign tumor with usual onset in young adulthood. The skull base is the most common site of occurrence although, less often, the tumors can appear at the falx cerebri or at the dural convexity. The differentiation of these lesions from meningiomas through imaging is generally difficult.
    Clinical case presentation and review of the current literature.
    We report a case of a 25-year-old male patient with a giant convexity chondroma with meningeal attachment in the right frontal lobe that was detected after a first generalized seizure. Based on the putative diagnosis of meningioma, the tumor was completely resected via an osteoplastic parasagittal craniotomy. The postoperative MRI confirmed the complete tumor resection. Histopathological analysis revealed the presence of a chondroma.
    Intracranial chondromas are a rarity and their preoperative diagnosis based on neuroimaging is difficult. In young patients and those with skeletal disease, the differential diagnosis of a chondroma should be considered. In symptomatic patients, operative resection is sensible. In most cases total removal of the tumor is possible and leads to full recovery. When the finding is merely incidental in older patients, a watchful waiting approach is acceptable, given the benign and slow-growing nature of the lesion.
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  • 文章类型: Journal Article
    A 55-year-old female presented to the emergency room with a complaint of aphasia. Her initial brain computed tomography scan showed an intracranial hemorrhage in the left frontal area. After surgery, histopathological examination confirmed the diagnosis of a chondroma. Intradural chondroma is a rare, slow growing, benign intracranial neoplasm, but is even rarer in combination with an intratumoral hemorrhage. Chondromas are generally avascular cartilaginous lesions. Our case was thought to be caused by the rupture of abnormally weak vessels derived from the friable tumor. Intradural chondromas may be included in the differential diagnosis of intracranial tumors with acute hemorrhages.
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  • 文章类型: Case Reports
    背景:颅内软骨瘤是罕见的良性肿瘤。我们报告了一名在妊娠中期偶然诊断为颅内软骨瘤的患者。
    方法:一名22岁的白种人被诊断为因机动车事故在入院期间发现的附带副烷烃病变。在录取之前,患者未出现任何神经系统症状.磁共振波谱(MRS)提示该颅内病变是良性的。决定将肿瘤切除推迟到分娩后。在剖腹产期间进行了特殊的麻醉考虑以维持稳定的血压和血容量。患者在产后两个月成功地完全切除了颅内肿瘤,没有任何术后缺陷。
    结论:这是首例妊娠期颅内猪旁软骨瘤的病例报告。这份报告强调了怀孕期间这种罕见类型肿瘤的病程。此病例说明了神经系统无症状患者的治疗的相关方面,该患者偶然发现了颅内肿瘤,MRS提示其良性性质。
    BACKGROUND: Intracranial chondromas are rare benign neoplasms. We report a patient incidentally diagnosed with an intracranial chondroma during her second trimester.
    METHODS: A 22-year-old Caucasian was diagnosed with an incidental parafalcine lesion found during admission due to a motor vehicle accident. Prior to the admission, the patient did not present with any neurological symptom. Magnetic resonance spectroscopy (MRS) suggested this intracranial lesion to be benign. A decision was made to delay the tumor excision until after delivery. Special anesthesia considerations were made to maintain stable blood pressure and euvolemia during the Cesarean section. The patient underwent a successful gross total removal of the intracranial tumor two months postpartum without any post-operative deficit.
    CONCLUSIONS: This is the first case report of an intracranial parafalcine chondroma in pregnancy. This report highlights the disease course of this rare type of tumor during pregnancy. This case illustrates relevant aspects of the management of a neurologically asymptomatic patient with an incidentally discovered intracranial tumor of which MRS suggested a benign nature.
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