intra-abdominal hemorrhage

腹腔内出血
  • 文章类型: Journal Article
    背景:通过超声早期发现腹腔出血对军事和平民创伤具有挽救生命的意义。然而,严格遵守光线纪律可能会禁止在部署环境中使用超声设备。此外,目前的夜视设备仍然与超声技术不兼容。这项研究旨在通过腹腔内出血模型评估一种创新的夜视设备,该设备具有超声功能,可在图片中显示图像,以识别停电条件下的不可压缩的躯干出血。
    方法:使用8个死猪胎儿标本,分为两组:腹腔内出血(n=4)和无出血(n=4)。通过将200mL生理盐水直接注射到腹膜腔中来模拟腹腔内出血。在停电的情况下,5名参与者使用原型具有超声功能的夜视设备对每个模型进行了创伤超声检查(FAST)检查的重点评估。
    结果:在进行的40次快速考试中,95%(N=38)导致正确识别腹腔内出血。在错误识别的考试中,两者都是假阳性,导致100%的灵敏度,90%特异性,91%阳性预测值,和100%阴性预测值。所有参与者都指出,这种新颖的设备易于使用,并为在停电条件下进行FAST考试提供了出色的可视化效果。
    结论:支持超声的夜视原型在识别不可压缩的躯干出血方面表现出了有希望的结果,同时在停电条件下保持严格的轻度纪律。应进一步研究工作,以评估提供者在停电条件下使用支持超声的原型夜视设备执行程序的能力。
    BACKGROUND: Early detection of abdominal hemorrhage via ultrasound has life-saving implications for military and civilian trauma. However, strict adherence to light discipline may prohibit the use of ultrasound devices in the deployed setting. Additionally, current night vision devices remain noncompatible with ultrasound technology. This study sought to assess an innovative night vision device with ultrasound capable picture-in-picture display via a intraabdominal hemorrhage model to identify noncompressible truncal hemorrhage in blackout conditions.
    METHODS: 8 post mortem fetal porcine specimens were used and divided into 2 groups: intrabdominal hemorrhage (n = 4) vs no hemorrhage (n = 4). Intrabdominal hemorrhage was modeled via direct injection of 200 mL of normal saline into the peritoneal cavity. Under blackout conditions, 5 participants performed a focused assessment with sonography for trauma (FAST) exam on each model using the prototype ultrasound-capable night vision device.
    RESULTS: Of the 40 FAST exams performed, 95% (N = 38) resulted in the correct identification of intraabdominal hemorrhage. Of the incorrectly identified exams, both were false positives resulting in a 100% sensitivity, 90% specificity, 91% positive predictive value, and a 100% negative predictive value. All participants noted the novel device was easy to use and provided superior visualization for performing FAST exams under blackout conditions.
    CONCLUSIONS: The ultrasound-enabled night vision prototype demonstrated promising results in identifying noncompressible truncal hemorrhage while maintaining strict light discipline in blackout conditions. Further research efforts should be directed at assessing the ability of providers to perform procedures in blackout conditions using the ultrasound-enabled prototype night vision device.
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  • 文章类型: Case Reports
    破裂引起的腹腔内出血,多囊性肝病(PCLD)患者的大型肝囊肿是罕见的,如果不及时治疗,可能会致命.以前只报告了一些孤立的病例。通常的患者概况包括接受抗凝治疗的老年患者,正如我们的案例所证明的那样。肝内囊肿大致分为先天性,创伤性,传染性,寄生,和肿瘤。先天性肝内囊肿可以由简单和PCLD组成,正如我们案例中概述的那样。单纯囊肿通常无症状,但偶尔它们可能会达到更大的尺寸,并导致并发症,如破裂,阻塞,感染,出血,甚至门静脉高压症.我们介绍了一个罕见的病例,一个78岁的利伐沙班PCLD患者最初表现为弥漫性腹痛,扩张,进展为血流动力学不稳定。计算机断层扫描(CT)扫描显示左肝叶囊肿破裂,导致腹膜积血并导致急腹症.该病例因患者的抗凝状态和异常的肝血管模式而复杂化。介入放射学(IR)成功地确定了异常出血血管,并通过超选择性线圈栓塞阻止了主动外渗。
    Intra-abdominal hemorrhage resulting from a ruptured, large hepatic cyst in a polycystic liver disease (PCLD) patient is rare and potentially fatal if not addressed promptly. Only a few isolated cases have previously been reported. The usual patient profile consists of elderly patients on anticoagulation, as is demonstrated in our case. Intra-hepatic cysts are broadly classified into congenital, traumatic, infectious, parasitic, and neoplastic. Congenital intra-hepatic cysts can consist of both simple and PCLD, as is outlined in our case. Simple cysts are usually asymptomatic, but occasionally they may achieve larger dimensions and lead to complications such as rupture, obstruction, infection, hemorrhage, and even portal hypertension. We present an uncommon case of a 78-year-old patient with PCLD on rivaroxaban who presented initially with diffuse abdominal pain, distension, and progression into hemodynamic instability. A computerized tomography (CT) scan revealed a ruptured left hepatic lobe cyst, causing hemoperitoneum and resulting in an acute abdomen. This case was complicated by the patient\'s anticoagulation status and anomalous hepatic vasculature pattern. Interventional radiology (IR) successfully identified the aberrant bleeding vessel and stopped the active extravasation with super-selective coil embolization.
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  • 文章类型: Review
    OBJECTIVE: This case report presented cases with spontaneous hemoperitoneum during pregnancy.
    METHODS: Case 1 presented with acute abdominal pain with signs of shock. Cases 2 and 3 both presented with stable vital signs and the sudden decline of fetal heart rate. Cesarean section was performed at 27, 36+4, and 34 gestational weeks, respectively. Bleeding sites were founded on the surface of the uterus or the parametrium. The perinatal outcome was stillbirth, live birth, and neonatal severe asphyxia.
    CONCLUSIONS: Careful physical examination, strict monitoring of vital signs, and timely surgical intervention are critical for improving the prognosis.
    OBJECTIVE: Este caso clínico presentó casos con hemoperitoneo espontáneo durante el embarazo.
    UNASSIGNED: El caso 1 presentó dolor abdominal agudo con signos de shock, los casos 2 y 3 se presentaron ambos con signos vitales estables y la disminución repentina de la frecuencia cardíaca fetal. La cesárea se realizó a las 27, 36 + 4 y 34 semanas de gestación, respectivamente. Los sitios de sangrado se encontraron en la superficie del útero o el parametrio.
    UNASSIGNED: Un control estricto de los signos vitales y una intervención quirúrgica oportuna son fundamentales para mejorar el pronóstico.
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  • 文章类型: Case Reports
    出血是胰腺切除术后的致命并发症。虽然线圈栓塞是一种广泛接受的治疗选择,应防止其余器官的缺血。这项研究报告了使用球囊辅助线圈栓塞(BACE)进行腹腔轴整块切除术(DP-CAR)成功治疗远端胰腺切除术后的腹腔内出血。一名59岁的男子被诊断出患有局部晚期胰腺癌。肿瘤累及肝总动脉,脾动脉,还有腹腔动脉.吉西他滨/nab-紫杉醇治疗四个周期后,软密度质量,围绕着动脉,缩水了.进行DP-CAR和R0切除。术后发生轻微胰瘘。术后六个月,计算机断层扫描显示位于胃十二指肠动脉汇合处附近的胰十二指肠上动脉(ASPDA)假性动脉瘤迟发性无症状出血.BACE是通过在ASPDA和胰十二指肠上动脉(PSPDA)汇合处放置微球导管来进行的,以防止线圈迁移。插入微球导管后,在ASPDA中进行线圈栓塞。从PSPDA维持肝血流。BACE是一种有用的技术,在胰腺远端切除术后进行线圈栓塞出血时,可以保护剩余器官的血流。尤其是在DP-CAR之后。
    Bleeding is a fatal complication after pancreatectomy. Although coil embolization is a widely accepted treatment option, ischemia of the remaining organs should be prevented. This study reports the successful treatment of intra-abdominal hemorrhage following distal pancreatectomy with en bloc celiac axis resection (DP-CAR) using balloon-assisted coil embolization (BACE). A 59-year-old man was diagnosed with locally advanced pancreatic cancer. The tumor involves the common hepatic artery, splenic artery, and celiac artery. After four cycles of treatment with gemcitabine/nab-paclitaxel, the soft-density masses, surrounding the artery, shrunk. DP-CAR and R0 resections were performed. A minor postoperative pancreatic fistula occurred. Six months postoperatively, the computed tomography showed delayed asymptomatic bleeding from an anterior superior pancreaticoduodenal artery (ASPDA) pseudoaneurysm located near the gastroduodenal artery confluence. BACE was performed by placing a microballoon catheter in the region of confluence of the ASPDA and posterior superior pancreaticoduodenal artery (PSPDA) to prevent coil migration. After inserting the microballoon catheter, coil embolization was performed in the ASPDA. Hepatic blood flow was maintained from the PSPDA. BACE is a useful technique to preserve blood flow to the remnant organs when performing coil embolization for bleeding following a distal pancreatectomy, especially following a DP-CAR.
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  • 文章类型: Case Reports
    肝血管瘤(HH)是一种先天性血管畸形,似乎是最可能的良性肝肿瘤,由大量的血管组成,排列和大小异常。在大多数情况下,HH无症状,患者预后良好。根据研究,肿块的位置和大小与症状和并发症相关。文献中关于HH自发破裂的报道较少。在这种紧急情况下,动态增强CT扫描,尤其是延迟成像的三相计算机断层扫描(CT),是首选。
    这里,我们介绍了两名中年女性自发性HH破裂患者。在增强CT和急诊手术的准确诊断后,病人恢复良好,出院。
    适当的影像学研究,尤其是增强CT,对于自发性HH破裂患者,急诊手术是必不可少的。作为一名外科医生,我们需要注意无症状的HH患者。
    UNASSIGNED: Hepatic hemangioma (HH) is a congenital vasal malformation that seemed like the most probable benign liver neoplasm, composed of masses of blood vessels, which are anomalous in arrangement and size. In most cases, HH is asymptomatic, and patients have an excellent prognosis. According to research, the location and size of the mass are correlated with the symptoms and complications. Reports of spontaneous rupture of HH have been less reported in the literature. In this emergency condition, dynamic contrast-enhanced CT scanning, especially triple-phase computed tomography (CT) with delayed imaging, is preferred.
    UNASSIGNED: Here, we presented two middle-aged female patients with spontaneous rupture of HH in our hospital. Following an accurate diagnosis of enhanced CT and emergency surgery, patients recovered well and were discharged from the hospital.
    UNASSIGNED: Appropriate imaging studies, especially enhanced CT, and emergency surgery are indispensable for patients with spontaneous rupture of HH. As a surgeon, we need to pay attention to the asymptomatic patient with HH.
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  • 文章类型: Case Reports
    一名71岁男子因左侧胸痛入院。他有糖尿病史,表皮生长因子受体-酪氨酸激酶抑制剂治疗晚期非小细胞肺癌,和皮质类固醇治疗潜在的肺部疾病。胸部计算机断层扫描显示双侧下叶合并,通过支气管镜检测到烟曲霉。怀疑是侵袭性肺曲霉病,并开始使用伏立康唑进行抗真菌治疗;然而,病人突然去世了。尸检显示,由于曲霉菌坏死性血管炎引起的脾动脉瘤破裂,散发性曲霉菌感染和腹腔内出血。这被认为是死因。
    A 71-year-old man was admitted for left-sided chest pain. He had a history of diabetes, treatment with epidermal growth factor receptor-tyrosine kinase inhibitor for advanced non-small-cell lung cancer, and corticosteroid treatment for underlying lung diseases. Chest computed tomography showed consolidations in the bilateral lower lobes, and Aspergillus fumigatus was detected by bronchoscopy. Invasive pulmonary aspergillosis was suspected, and antifungal therapy with voriconazole was initiated; however, the patient passed away suddenly. Autopsy revealed disseminated Aspergillus infection and intra-abdominal hemorrhage due to the rupture of a splenic vein aneurysm caused by Aspergillus necrotizing vasculitis, which was considered the cause of death.
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  • 文章类型: Case Reports
    An 8-year-old Ragdoll cat was admitted to our hospital after its owner noticed sudden lethargy. Abdominal ultrasonography showed a large amount of blood in the abdominal cavity, and the cat was diagnosed as having hemorrhagic shock caused by the rupture of an intra-abdominal mass. Blood transfusion was performed on the 1st day of hospitalization. On the 2nd day, contrast-enhanced computed tomography (CT) was performed, and hemorrhage from a mass originating in the caudate lobe of the liver was noted. Transcatheter arterial embolization (TAE) was performed to stop the bleeding from the mass using Gelpart to embolize the feeding artery. The following day, fever and elevation of liver enzyme levels were observed, but these subsided within a few days. At discharge 5 days after TAE, no fluid was found in the peritoneal cavity, and no further intra-abdominal bleeding occurred. Sixty-six days after TAE, we were able to perform resection surgery with the cat in good condition. A partial response was observed on CT performed before surgery. Histopathology revealed cholangiocellular adenoma. The cat was doing well as of postoperative day 549. This case indicates that TAE may be effective for initial hemostasis and stabilization of conditions in animals with tumor-induced hemorrhage.
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  • 文章类型: Journal Article
    18F标记的血池剂(BPA)在识别出血部位方面引起了极大的关注。然而,由于标记方法的局限性,许多BPA没有得到充分的评估。在我们之前的工作中,我们注意到18F-PEG1-乙烯基砜(18F-VS)可以有效地标记离体和原位红细胞(RBC)。然而,其作为双酚A的应用尚未得到充分评估。在这项研究中,我们系统地探讨了使用18F-VS标记的红细胞作为正电子发射断层扫描(PET)BPA诊断腹腔内出血的可行性.简而言之,我们首先优化了标签条件,在37°C下与18F-VS在磷酸盐缓冲盐水(PBS)中孵育20分钟后,其导致80%标记产率的RBC。发现18F-VS标记的红细胞在体外是稳定的,这可以简化其体内应用的运输/储存。在正常大鼠PET研究中,心血管系统可以清楚地成像长达5小时后注射(p.i.)。腹腔内出血大鼠模型表明,18F-VS标记的红细胞清楚地显示了由于腹腔内出血引起的血管外放射性的动态变化。在消化道出血模型中的验证清楚地证明了使用18F-VS标记的红细胞作为BPA的巨大潜力,这可以在未来的研究中进一步评估。
    18F-Labeled blood pool agents (BPAs) have attracted great attention for identifying bleeding sites. However, many BPAs are not sufficiently evaluated partially due to the limitations of labeling methods. In our previous work, we noticed that 18F-PEG1-vinyl sulfone (18F-VS) could efficiently label red blood cells (RBCs) ex vivo and in situ. However, its application as BPA is not fully evaluated. In this study, we systematically explored the feasibility of using 18F-VS-labeled RBCs as a positron emission tomography (PET) BPA for intra-abdominal bleeding diagnosis. In brief, we first optimized the labeling conditions, which lead to an 80% labeling yield of RBCs after incubating with 18F-VS in phosphate-buffered saline (PBS) at 37°C for 20 min. 18F-VS-labeled RBCs were found to be stable in vitro, which could simplify its transportation/storage for in vivo applications. In normal rat PET study, the cardiovascular system could be clearly imaged up to 5 h post injection (p.i.). An intra-abdominal hemorrhage rat model demonstrated that the 18F-VS-labeled RBCs clearly showed the dynamic changes of extravascular radioactivity due to intra-abdominal hemorrhage. Validation in the model of gastrointestinal bleeding clearly demonstrated the great potential of using 18F-VS-labeled RBCs as a BPA, which could be further evaluated in future studies.
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  • 文章类型: Case Reports
    新生儿腹腔内出血在文献中很少报道。我们报道一例新生儿脾损伤,强调高指数怀疑在早期识别这种罕见且可能致命的伤害中的重要性。我们报告了第一例新生儿脾破裂并接受了成功的血管内治疗。
    Neonatal intra-abdominal hemorrhage has been rarely reported in the literature. We report a case of splenic injury in a neonate, highlighting the importance of a high-index suspicion in early recognition of this rare and potentially fatal injury. We report the first case of a neonate who had a splenic rupture and underwent successful endovascular treatment.
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  • 文章类型: Case Reports
    BACKGROUND: Hepatic inflammatory pseudotumor (HIPT) is an uncommon benign tumor-like mass that mimics malignant tumors.
    METHODS: A 73-year-old man was admitted with severe epigastric pain and high fever. He had received choledocojejunostomy. Enhanced computed tomography showed a 76 mm, heterogeneous, gradual enhanced low-density mass in the caudate lobe and hyperdense fluid was detected around the mass. Based on the diagnosis of hemorrhage from a hypervascular malignant liver tumor, chemoembolization was conducted. Antibiotics (Meropenem) were administered for 2 weeks, and methylprednisolone (125 mg) was administered twice as a premedication for chemoembolization. After the 2nd chemoembolization, rapid tumor shrinkage was observed and the inflammatory changes gradually disappeared. The tumor was finally diagnosed as fibrohistiocytic type HIPT with an ultrasound-guided percutaneous tumor biopsy. The diameter of the liver tumor decreased to 15 mm and intra-abdominal hemorrhage disappeared in 3 months.
    CONCLUSIONS: Development of HIPT can be associated with intra-abdominal hemorrhage.
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