■我们已经证明,可以通过平衡双眼同时观看时所需的眼间亮度差来量化不平衡眼间抑制的深度。在这项研究中,我们旨在研究这种方法在间歇性外斜视(IXT)儿童中的适用性,提供双眼失衡患者眼间抑制的定量评估。此外,我们评估了其与IXT临床特征的相关性。
使用偏振器和中性密度(ND)滤光片定量测量IXT中的眼间抑制。ND滤光片的密度从0.3ND递增调整到3ND,步长为0.3ND(共10级)。我们的前瞻性研究涉及46名IXT患者(平均年龄:10.12±4.89岁;平均±SD)和24名正常观察者(平均年龄:7.88±1.83岁)。
■抑制试验表现出良好的重测可靠性,统计分析支持。与对照组相比,我们在IXT患者中观察到更明显的眼间抑制。值得注意的是,在IXT中,远距离和近距离观察的抑制幅度显着不同(1.55±0.93与0.57±0.64;Z=4.764,p<0.001)。此外,我们确定了眼间抑制与Worth-4-Dot检验获得的数据之间存在正相关.此外,眼间抑制与距离控制评分显著相关.
■我们的新颖测试提供了一种方便可靠的方法来量化IXT患者的眼间抑制。眼间抑制的定量评估提供了评估IXT临床特征的敏感工具。
UNASSIGNED: We have demonstrated that the depth of unbalanced interocular suppression can be quantified by balancing the interocular luminance differences required when both eyes are viewing simultaneously. In this study, we aimed to investigate the applicability of this method in children with intermittent exotropia (IXT), offering a quantitative assessment of interocular suppression in individuals with binocular imbalance. Additionally, we evaluated its association with the clinical characteristics of IXT.
UNASSIGNED: Interocular suppression in IXT was quantitatively measured using a polarizer and neutral-density (ND) filters. The density of the ND filter was adjusted incrementally from 0.3ND to 3ND, with a step size of 0.3ND (a total of 10 levels). Our prospective study involved 46 patients with IXT (mean age: 10.12 ± 4.89 years; mean ± SD) and 24 normal observers (mean age: 7.88 ± 1.83 years).
UNASSIGNED: The suppression test exhibited good test-retest reliability, supported by statistical analysis. We observed more pronounced interocular suppression in individuals with IXT compared to controls. Notably, the magnitude of suppression during distant and near viewing significantly differed in IXT (1.55 ± 0.93 vs. 0.57 ± 0.64; Z = 4.764, p < 0.001). Furthermore, we identified a positive correlation between interocular suppression and data obtained from the Worth-4-Dot test. Additionally, interocular suppression showed a significant association with distance control scores.
UNASSIGNED: Our novel test offers a convenient and reliable means to quantify interocular suppression in patients with IXT. The quantitative assessment of interocular suppression provides a sensitive tool to evaluate the clinical characteristics of IXT.