international consensus

国际共识
  • 文章类型: Journal Article
    目的:通过不同学科专家的意见,确定住院患者外周静脉导管(PVC)相关性静脉炎管理相关护理实践的共识和重要性。
    背景:PVC通常用于医院,但与静脉炎等并发症有关。他们的管理差异很大,研究是异质的。
    方法:德尔菲法。
    方法:四个阶段:问题领域(2022年7月,WebofScience文献计量学综述),小组成员,两个Delphi回合和结束标准。在Delphi调查中,专家根据评估回答了在线问卷,治疗和随访维度(2022年9月-2023年2月)。对频率进行了统计分析,百分比,测量中心趋势和分散水平(QD)。创建了一个注释空间,并对它们进行了主题分析。
    结果:18位专家(护士,医生和药剂师)参加了Delphi回合。确定了45项活动:19项在评估中,治疗中15例,随访中11例。在五个活动中发现了较高的共识水平(QD≤0.6)(11.12%),中等水平(0.61.0)21(46.66%)。确定了七个主题(患者视角,缺乏共识,低循证实践,分阶段治疗,预防活动,实践和专家团队以及跨学科工作的高度可变性)。
    结论:系统评估量表的重要性与体征和症状(疼痛,发红,炎症,明显的脐带和硬结)。强调根据严重程度和日常视觉记录和监测进行治疗,同时需要患者参与和医疗保健素养。11%的活动达成了高度共识,显示静脉炎管理的标准和干预措施差异很大。突出的需求包括在团队中工作,使用专家团队并促进基于证据和预防的活动。
    结论:注意到临床变异性,因此,关于PVC静脉炎标准化护理和循证实践的共识的重要性。
    德尔菲研究(CRDES)。
    专家贡献。
    OBJECTIVE: To determine the consensus and importance of care practices related to the management of peripheral venous catheter (PVC)-related phlebitis in hospitalized patients through the views of experts from different disciplines.
    BACKGROUND: PVCs are commonly used in hospitals but are associated with complications such as phlebitis. Their management differs widely, and studies are heterogeneous.
    METHODS: Delphi method.
    METHODS: Four stages: problem area (with Web of Science bibliometric review in July 2022), panel members, two Delphi rounds and closing criteria. In the Delphi survey, experts answered an online questionnaire based on assessment, treatment and follow-up dimensions (September 2022-February 2023). Statistical analyses were conducted of frequencies, percentages, measures of central tendency and levels of dispersion (QD). A space for comments was created, and a thematic analysis conducted of them.
    RESULTS: Eighteen experts (nurses, doctors and pharmacists) participated in the Delphi rounds. Forty-five activities were identified: 19 in assessment, 15 in treatment and 11 in follow-up. A high consensus level (QD ≤ 0.6) was found in five activities (11.12%), moderate level (0.6 < QD < 1.0) in 19 (42.22%) and low level (QD > 1.0) in 21 (46.66%). Seven themes were determined (patient perspective, lack of consensus, low evidence-based practices, stage-based treatments, prevention activities, high variability in practice and specialist teams and interdisciplinary work).
    CONCLUSIONS: The importance of systematic assessment scales is highlighted together with consensus on signs and symptoms (pain, redness, inflammation, palpable cord and induration). Treatment according to severity and daily visual recording and monitoring are emphasized along with the need for patient participation and healthcare literacy. A high level of consensus was obtained in 11% of the activities, showing the large variability of criteria and interventions for phlebitis management. Highlighted needs include working in a team, the use of specialist teams and promoting evidence- and prevention-based activities.
    CONCLUSIONS: Clinical variability is noted and, therefore, the importance of consensus on standardized care for PVC phlebitis and evidence-based practice.
    UNASSIGNED: Delphi studies (CREDES).
    UNASSIGNED: Experts contribution.
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  • 文章类型: Journal Article
    身体活动和运动(PAS)与许多健康结果和社会效益有关。本研究的主要目的是建立基于专家意见的PAS的社会投资回报(SROI)模型,以阐明影响领域以及如何衡量和评估它们。
    将采用Delphi方法,对适用于PAS的SROI框架进行系统审查,并与专家进行初步访谈,以告知Delphi调查声明的设计。将与专家小组进行三轮迭代沟通。参与者将以五点李克特量表表示他们对每个声明的同意程度。在第二轮和第三轮迭代中,专家们将重新评估这些陈述,并将获得小组回应的摘要。在第3轮后,如果≥70%的小组同意/强烈同意或不同意/强烈不同意,则声明将达成共识。最后,将举行小组会议(3-4名专家),询问每个领域的计量和估值方法。
    该项目的最终目标将导致为组织设计工具包,专业人士,以及决策者如何衡量考绩制度的社会效益。
    UNASSIGNED: Physical activity and sport (PAS) have been related to many health outcomes and social benefits. The main aim of this research is to build a Social Return on Investment (SROI) model of PAS based on experts\' opinion to clarify the domains of impact and how to measure and value them.
    UNASSIGNED: A Delphi method will be employed with a systematic review on the SROI framework applied to PAS and initial interviews with experts informing the design of the Delphi survey statements. Three iterative rounds of communication with the expert panel will be carried out. Participants will indicate their level of agreement with each statement on a five-point Likert scale. During the second and third iterative rounds, experts will reappraise the statements and will be provided with a summary of the group responses from the panel. A statement will have reached consensus if ≥70% of the panel agree/strongly agree or disagree/strongly disagree after round 3. Finally, group meetings (3-4 experts) will be conducted to ask about the measurement and valuation methods for each domain.
    UNASSIGNED: The final goal of this project will result in the design of a toolkit for organizations, professionals, and policymakers on how to measure the social benefits of PAS.
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  • 文章类型: Journal Article
    目前,目前尚无确定患者是否符合坏疽性脓皮病(PG)临床试验的标准指南.因此,我们的目标是确定哪些临床特征(CF),组织病理学(HP)特征,对于未治疗(TN)患者和已经接受免疫调节药物治疗(治疗暴露(TE))的患者,或实验室特征应纳入活动性溃疡性PG临床试验合格标准.这项研究采用了四轮Delphi技术。对21位国际委员会认证的皮肤科医生和整形外科医生PG专家进行了电子调查(6/2022-12/2022)。我们的结果表明,对于有资格参加PG试验的患者,他们必须符合以下标准:1)存在溃疡,红斑/暴力破坏伤口边界,2)存在疼痛或招标溃疡,3)快速进展疾病的历史/存在,4)排除感染和其他皮肤溃疡的原因,5)活检苏木精和伊红染色,和6)pathergy的存在/历史。这些标准对于TN与TE患者的重要性不同。鉴于国际群体,我们无法促进两轮之间的现场讨论。这项Delphi共识研究提供了一组具体的,PG临床试验的标准化合格标准,从而解决了阻碍FDA批准PG药物进展的主要问题之一。
    At present, there are no standardized guidelines for determining patient eligibility for pyoderma gangrenosum (PG) clinical trials. Thus, we aim to determine which clinical features, histopathological features, or laboratory features should be included in active ulcerative PG clinical trial eligibility criteria for treatment-naïve patients and patients already treated with immunomodulating medications (treatment-exposed patients). This study employed 4 rounds of the Delphi technique. Electronic surveys were administered to 21 international board-certified dermatologists and plastic surgeon PG experts (June 2022-December 2022). Our results demonstrated that for a patient to be eligible for a PG trial, they must meet the following criteria: (i) presence of ulcer(s) with erythematous/violaceous undermining wound borders, (ii) presence of a painful or tender ulcer, (iii) history/presence of rapidly progressing disease, (iv) exclusion of infection and other causes of cutaneous ulceration, (v) biopsy for H&E staining, and (vi) a presence/history of pathergy. These criteria vary in importance for treatment-naïve versus treatment-exposed patients. Given the international cohort, we were unable to facilitate live discussions between rounds. This Delphi consensus study provides a set of specific, standardized eligibility criteria for PG clinical trials, thus addressing one of the main issues hampering progress toward Food and Drug Administration approval of medications for PG.
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  • 文章类型: Journal Article
    背景:化脓性脊柱感染(PSIs)是具有高发病率和死亡率的严重疾病。如果治疗失败,患者可能需要手术,但是对于医疗失败的定义尚无共识。
    目的:通过专家的国际共识,确定PSI医学治疗失败的定义标准。
    方法:两轮基本德尔菲法研究。
    方法:来自22个国家的150名专家(临床指南的作者或共同作者或关于该主题的索引出版物)被邀请参加;33名回答了定义标准的两轮。
    方法:将1至9的量表(1:无相关性;9:高度相关)应用于每个标准。
    方法:我们创建了一项在线调查,其中包含文献中报道的10项标准,以定义PSIs的药物治疗失败。我们通过电子邮件将此调查发送给专家。确定参与者对相关标准的一致性(得分≥7)。两个月后,第二轮评估已经发送。纳入了第一轮中六名响应者建议的额外标准。最终版本的标准被认为是相关的,并达成了高度一致。
    结果:共识定义是:1)尽管进行了广谱抗生素治疗,但仍存在不受控制的脓毒症,2)感染复发,在为期六周的抗生素治疗后,临床和实验室有所改善。
    结论:我们对PSI非手术治疗后失败的定义可以提供一种指导临床决策的标准化方法。此外,它有可能加强这一领域的科学报告。
    Pyogenic spinal infections (PSIs) are severe conditions with high morbidity and mortality. If medical treatment fails, patients may require surgery, but there is no consensus regarding the definition of medical treatment failure.
    To determine criteria for defining failure of medical treatment in PSI through an international consensus of experts.
    A two-round basic Delphi method study.
    One hundred and fifty experts from 22 countries (authors or co-authors of clinical guidelines or indexed publications on the topic) were invited to participate; 33 answered both rounds defining the criteria.
    A scale of 1 to 9 (1: no relevance; 9: highly relevant) applied to each criterion.
    We created an online survey with 10 criteria reported in the literature to define the failure of medical treatment in PSIs. We sent this survey via email to the experts. Agreement among the participants on relevant criteria (score ≥7) was determined. One month later, the second round of evaluations was sent. An extra criterion suggested by six responders in the first round was incorporated. The final version was reached with the criteria considered relevant and with high agreement.
    The consensus definition is: (1) There is an uncontrolled sepsis despite broad spectrum antibiotic treatment, and (2) There is an infection relapse, following a six-week period of antibiotics with clinical and laboratory improvement.
    Our definition of failure following nonsurgical treatment of PSI can offer a standardized approach to guide clinical decision-making. Furthermore, it has the potential to enhance scientific reporting within this field.
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  • 文章类型: Journal Article
    目的:建立在我们最近开发的关于口腔虚弱(与年龄相关的口腔面部结构功能下降)的概念定义的基础上,这项e-Delphi研究旨在通过识别口腔脆弱的组成部分来制定口腔脆弱的操作定义。
    方法:我们使用了改进的e-Delphi研究,以在国际专家之间就口腔虚弱的成分达成共识。十五名受邀的老年牙学领域专家中有十二名参加了会议。专家们回答了三轮在线5点量表问卷,其中包括或排除在口头脆弱的操作定义之外。每一轮之后,分数和基本原理与所有专家分享,之后,他们可以修改自己的立场。当至少70%的专家同意是否应将一个组成部分纳入口头脆弱的操作定义时,达成了共识。
    结果:专家们在包括八种口腔虚弱成分而不包括十九种方面达成了很高的共识(80-100%)。口腔虚弱的操作定义应包括以下组成部分:1)难以进食坚硬或坚韧的食物,2)不能咀嚼所有类型的食物,3)吞咽固体食物的能力下降,4)吞咽液体的能力下降,5)整体吞咽功能差,6)舌头运动受损,7)言语或发声障碍,和8)唾液分泌不足或口干症。
    结论:这项e-Delphi研究提供了构成口头虚弱的操作定义的八个组成部分。这些组件是下一阶段的基础,这包括开发一种口头虚弱评估工具。
    Building upon our recently developed conceptual definition of oral frailty (the age-related functional decline of orofacial structures), this e-Delphi study aims to develop an operational definition of oral frailty by identifying its components.
    We used a modified e-Delphi study to reach a consensus among international experts on the components of oral frailty. Twelve out of fifteen invited experts in the field of gerodontology participated. Experts responded to three rounds of an online 5-point scale questionnaire of components to be included or excluded from the operational definition of oral frailty. After each round, scores and rationales were shared with all experts, after which they could revise their position. A consensus was reached when at least 70% of the experts agreed on whether or not a component should be included in the operational definition of oral frailty.
    The experts achieved a high level of agreement (80 - 100%) on including eight components of oral frailty and excluding nineteen. The operational definition of oral frailty should include the following components: 1) difficulty eating hard or tough foods, 2) inability to chew all types of foods, 3) decreased ability to swallow solid foods, 4) decreased ability to swallow liquids, 5) overall poor swallowing function, 6) impaired tongue movement, 7) speech or phonatory disorders, and 8) hyposalivation or xerostomia.
    This e-Delphi study provided eight components that make up the operational definition of oral frailty. These components are the foundation for the next stage, which involves developing an oral frailty assessment tool.
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  • 文章类型: Published Erratum
    [这更正了文章DOI:10.3389/fphys.2023.1174103。].
    [This corrects the article DOI: 10.3389/fphys.2023.1174103.].
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  • 文章类型: Journal Article
    全身肌电刺激(WB-EMS)是一种训练技术,可以同时刺激所有主要肌肉群,每个电极具有特定的脉冲强度。WB-EMS的相应时间效率和联合友好性对于不能或没有动机进行(密集)常规训练协议的人来说可能是特别有吸引力的。然而,由于WB-EMS的巨大代谢和肌肉骨骼影响,必须特别注意该技术的应用。在过去,一些科学和报纸文章报道了WB-EMS的严重不良反应。为了提高商业非医疗WB-EMS应用的安全性,“安全有效的全身肌电刺激”的建议于2016年推出。然而,新的发展和趋势需要对这些建议进行更新,以纳入更多的国际专业知识,并在应用WB-EMS方面获得了丰富的经验。这些基于共识的建议的新版本已分为1)“WB-EMS的一般方面”,2)“培训准备”,建议3)“WB-EMS应用程序”本身和4)“培训期间和之后的安全方面”。特别涉及的关键主题是1)对WB-EMS应用的一致和密切监督,2)WB-EMS培训师的强制性资格,3)WB-EMS之前的记忆和对禁忌症的相应考虑,4)参与者对会议的适当准备,5)精心准备的WB-EMS新手,6)WB-EMS会话之间的适当再生期,以及7)训练者和参与者之间在近距离物理距离上的连续互动。总之,我们相信,本指南将有助于提高非医疗商业WB-EMS应用领域的安全性和有效性.
    Whole-Body Electromyostimulation (WB-EMS) is a training technology that enables simultaneous stimulation of all the main muscle groups with a specific impulse intensity for each electrode. The corresponding time-efficiency and joint-friendliness of WB-EMS may be particularly attractive for people unable or unmotivated to conduct (intense) conventional training protocols. However, due to the enormous metabolic and musculoskeletal impact of WB-EMS, particular attention must be paid to the application of this technology. In the past, several scientific and newspaper articles reported severe adverse effects of WB-EMS. To increase the safety of commercial non-medical WB-EMS application, recommendations \"for safe and effective whole-body electromyostimulation\" were launched in 2016. However, new developments and trends require an update of these recommendations to incorporate more international expertise with demonstrated experience in the application of WB-EMS. The new version of these consensus-based recommendations has been structured into 1) \"general aspects of WB-EMS\", 2) \"preparation for training\", recommendations for the 3) \"WB-EMS application\" itself and 4) \"safety aspects during and after training\". Key topics particularly addressed are 1) consistent and close supervision of WB-EMS application, 2) mandatory qualification of WB-EMS trainers, 3) anamnesis and corresponding consideration of contraindications prior to WB-EMS, 4) the participant\'s proper preparation for the session, 5) careful preparation of the WB-EMS novice, 6) appropriate regeneration periods between WB-EMS sessions and 7) continuous interaction between trainer and participant at a close physical distance. In summary, we are convinced that the present guideline will contribute to greater safety and effectiveness in the area of non-medical commercial WB-EMS application.
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  • 文章类型: Journal Article
    目的:就乳腺癌相关淋巴水肿(BCRL)的多学科预防达成共识,考虑到来自世界各地参与乳腺癌识别和治疗的专业团体的专家意见。
    方法:国际共识研究,涉及改良的名义组和德尔菲过程。名义组总共确定了50种预防策略,这些策略代表了涉及乳腺癌护理的一系列健康学科所使用的策略。这些策略分为四个子组(一般性建议,治疗方法,康复医学,理疗和饮食建议),并在两轮德尔菲过程中以调查形式提交给多学科专家小组。11个专业领域和15个国家派代表参加了小组讨论。
    结果:二十七位专家对这两轮德尔菲做出了回应,第二轮后的平均总体协议为85.7%。在建议的50种预防BCRL的策略中,48位专家达成共识。
    结论:我们报告了关于多学科预防BCRL的国际共识,制定旨在系统化乳腺癌妇女护理的建议。共识可以为制定标准化临床指南提供平台。
    OBJECTIVE: To establish a consensus regarding the multidisciplinary prevention of breast cancer-related lymphedema (BCRL), taking into account the expert opinion of professional groups from across the world involved in the identification and treatment of breast cancers.
    METHODS: International consensus study involving a modified nominal group and Delphi process. A total of 50 preventive strategies representing those used by a range of health disciplines involved in breast cancer care were identified by the nominal group. These strategies were categorised into four subgroups (general recommendations, therapeutic approach, rehabilitation medicine and physiotherapy and dietary recommendations) and presented in survey format to a multidisciplinary panel of experts in a two-round Delphi process. Eleven specialist areas and 15 countries were represented on the panel.
    RESULTS: Twenty-seven experts responded to both Delphi rounds, and the mean overall agreement after Round 2 was 85.7%. Of the 50 proposed strategies for preventing BCRL, 48 yielded consensus among experts.
    CONCLUSIONS: We report an international consensus for the multidisciplinary prevention of BCRL, setting out recommendations aimed at systematising the care of women with breast cancer. The consensus could provide a platform for the development of standardised clinical guidelines.
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  • 文章类型: Consensus Development Conference
    远程医疗作为医院环境中患者护理的另一种工具的实施对于任何医疗保健系统来说都是一个挑战。鉴于困难和局限性,国际内科学论坛(FIMI,以西班牙语缩写)与来自欧洲和美洲17个国家的20个科学学会赞助了这份共识文件。目的是提出一个总体框架,允许在医院临床护理中开发和实施远程医疗,这将对FIMI成员国有用。我们提交的文件包括FIMI在其执行摘要中提出的建议,这些建议旨在保证有效,安全,高效,可持续,以及基于现有最佳科学证据的比例医疗干预措施。作者认为,该文件必须在最多两年内更新。
    The implementation of telemedicine as another tool for patient care in the hospital setting is a challenge for any healthcare system. Given the difficulties and limitations, the International Forum on Internal Medicine (FIMI, for its initials in Spanish) has sponsored this consensus document with 20 scientific societies from 17 countries in Europe and the Americas. The aim was to propose a general framework that allows for the development and implementation of telemedicine in hospital clinical care that would be useful to FIMI member countries. The document we present includes recommendations from the FIMI in its executive summary that intend to guarantee effective, safe, efficient, sustainable, and proportional healthcare interventions based on the best scientific evidence available. The authors believe that this document must be updated within a maximum period of two years.
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  • 文章类型: Consensus Development Conference
    文件对于质量改进很重要,教育,和研究。目前缺乏关于区域麻醉文件关键方面的建议。这项研究的目的是建立区域麻醉文件的建议。
    在执行委员会成立和定向文献回顾之后,创建了一长串潜在的文档组件。然后采用了改良的Delphi程序,以在区域麻醉的国际专家小组之间达成共识。这包括两轮匿名电子投票和最后的虚拟圆桌会议讨论,对前几轮尚未排除或接受的项目进行实时投票。通过回合进行或排除潜在组成部分是基于达成强烈共识。强共识定义为≥75%的一致性,弱共识定义为50%-74%的一致性。
    77名合作者参加了第1轮和第2轮,而50名合作者参加了第3轮。总的来说,专家就83个项目进行了投票,并就51个项目达成了强烈共识,对3的微弱共识和拒绝29。
    通过修改的Delphi过程,我们已经就区域麻醉文件建立了专家共识。
    Documentation is important for quality improvement, education, and research. There is currently a lack of recommendations regarding key aspects of documentation in regional anesthesia. The aim of this study was to establish recommendations for documentation in regional anesthesia.
    Following the formation of the executive committee and a directed literature review, a long list of potential documentation components was created. A modified Delphi process was then employed to achieve consensus amongst a group of international experts in regional anesthesia. This consisted of 2 rounds of anonymous electronic voting and a final virtual round table discussion with live polling on items not yet excluded or accepted from previous rounds. Progression or exclusion of potential components through the rounds was based on the achievement of strong consensus. Strong consensus was defined as ≥75% agreement and weak consensus as 50%-74% agreement.
    Seventy-seven collaborators participated in both rounds 1 and 2, while 50 collaborators took part in round 3. In total, experts voted on 83 items and achieved a strong consensus on 51 items, weak consensus on 3 and rejected 29.
    By means of a modified Delphi process, we have established expert consensus on documentation in regional anesthesia.
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