背景技术免疫系统,由各种分子和细胞组成,保护人类免受癌症和病原体的侵害。违反宽容,称为自身免疫性疾病(AD),是这些疾病的根源。系统性红斑狼疮(SLE)是一种以慢性炎症为特征的自身免疫性疾病,导致各种器官系统的组织损伤。这种疾病受荷尔蒙的影响,环境,和遗传因素。病理生理学尚不清楚,20%到30%的患者患有持续性疾病。SLE对年轻女性的影响大于男性,治疗集中于器官表现。尽管进步和更好的诊断,SLE继续显著增加发病率和早期死亡率。目的本研究旨在评估吉达地区普通人群对SLE的认识。沙特阿拉伯。方法使用GoogleForms对18岁及以上的吉达居民进行在线横断面调查。该调查从2023年8月到2023年10月开放给回复。结果该研究包括479名参与者,19(25%)男性和57(75%)女性诊断为SLE。这些人中大多数是家庭主妇和失业者。大多数人已婚(46,60.5%),只有25人(32.9%)是单身。在健康的参与者中,男性173人(42.9%),女性230人(57.1%),大多数是家庭主妇和政府雇员(95%,23.6%)。单打占124(30.8%),已婚人士占253人(62.8%)。在健康人群中,254(63%)缺乏关于SLE治疗的知识,而40例(52.6%)SLE患者认为联合化疗,疟疾药物,类固醇是最好的治疗方法.研究发现,393(82%)的样本听说过SLE,和250(52%)认为这不是一种传染性疾病。超过30人没有意识到SLE。大多数受访者认为他们需要对SLE有更多的认识和健康促进,410人(85.77%)表示他们需要更多的晋升。大多数人认为SLE在某种程度上是危险的。结论本研究揭示了吉达普通社区对SLE的认识的必要性和必要性。我们提倡开展疾病意识计划和活动,以增加吉达市对SLE的一般社区知识和认识。
Background The immune system, composed of various molecules and cells, protects humans from cancer and pathogens. A breach of tolerance, known as autoimmune disease (AD), is the root of these diseases. Systemic lupus erythematosus (SLE) is an autoimmune condition characterized by chronic inflammation, causing tissue damage in various organ systems. The disease is influenced by hormonal, environmental, and genetic factors. The pathophysiology is unclear, and 20% to 30% of patients have a persistent illness. SLE affects young females more than males, and treatments focus on organ manifestations. Despite advancements and better diagnoses, SLE continues to contribute significantly to morbidity and early mortality. Objective This study aims to assess knowledge of SLE among the general population of Jeddah, Saudi Arabia. Methodology An online cross-sectional survey using Google Forms was conducted for Jeddah residents aged 18 and above. The survey was open for responses from August 2023 to October 2023. Results The study included 479 participants, with 19 (25%) males and 57 (75%) females diagnosed with SLE. The majority of these individuals were housewives and unemployed. The majority were married (46, 60.5%), with only 25 (32.9%) being single. Among healthy participants, there were 173 (42.9%) males and 230 (57.1%) females, with a majority being housewives and government employees (95, 23.6%). Singles accounted for 124 (30.8%), while married individuals constituted 253 (62.8%). Among the healthy population respondents, 254 (63%) lacked knowledge about SLE treatment, while 40 (52.6%) SLE patients believed that a combination of chemotherapy, malaria medication, and steroids was the best treatment. The study found that 393 (82%) of the sample had heard about SLE, and 250 (52%) believed it was not a contagious disease. More than 30 were unaware of SLE. The majority of the respondents felt they needed more awareness and health promotion about SLE, with 410 (85.77%) stating they needed more promotion. The majority of the people believed SLE was dangerous to some extent. Conclusions This study revealed the need and necessity of awareness of SLE among the general community of Jeddah. We advocate undertaking disease awareness programs and activities to increase general community knowledge and awareness of SLE in the city of Jeddah.