纳米技术策略的使用是当前的热门话题,在化妆品行业中,该领域的研究已经显着增长。无机纳米粒子因其独特的物理化学性质而在这种情况下脱颖而出,特别是导致增加的折射率和吸收能力,使它们具有广泛的皮肤应用潜力,并使它们在皮肤药物和化妆品目的的研究中具有特殊的兴趣。这种性能是其大量包含在皮肤保健产品如防晒霜的制造中的原因,乳液,美容霜,皮肤软膏,化妆和其他人。特别是,它们合适的带隙能量特性允许它们用作光催化半导体。他们提供优异的紫外线吸收,通常被称为紫外线过滤器,并且负责其在世界范围内广泛用于防晒制剂中,在消费者施用后没有不期望的白色残留物。此外,基于无机纳米颗粒的化妆品具有与配方开发相关的几个附加特性,例如与其他纳米材料相比更便宜,具有更大的稳定性,并确保减少刺激,瘙痒,和皮肤过敏倾向。这篇综述将详细讨论用于皮肤药物和化妆品产品的主要无机纳米粒子,如二氧化钛,氧化锌,二氧化硅,银,黄金,铜,和铝纳米颗粒,纳米晶体,和量子点,报告它们的物理化学特征,还有它们的其他固有特性,这些特性有助于它们在这种类型的制剂中的使用。关于无机纳米粒子的安全问题,基于毒性研究,对人类和环境来说,以及与它们在皮肤药物和化妆品中的使用相关的监管事务,将被解决。
The use of nanotechnology strategies is a current hot topic, and research in this field has been growing significantly in the cosmetics industry. Inorganic nanoparticles stand out in this context for their distinctive physicochemical properties, leading in particular to an increased refractive index and absorption capacity giving them a broad potential for cutaneous applications and making them of special interest in research for dermopharmaceutical and cosmetic purposes. This performance is responsible for its heavy inclusion in the manufacture of skin health products such as sunscreens, lotions, beauty creams, skin ointments, makeup, and others. In particular, their suitable bandgap energy characteristics allow them to be used as photocatalytic semiconductors. They provide excellent UV absorption, commonly known as UV filters, and are responsible for their wide worldwide use in sunscreen formulations without the undesirable white residue after consumer application. In addition, cosmetics based on inorganic nanoparticles have several additional characteristics relevant to formulation development, such as being less expensive compared to other nanomaterials, having greater stability, and ensuring less irritation, itching, and propensity for skin allergies. This review will address in detail the main inorganic nanoparticles used in dermopharmaceutical and cosmetic products, such as titanium dioxide, zinc oxide, silicon dioxide, silver, gold, copper, and aluminum nanoparticles, nanocrystals, and quantum dots, reporting their physicochemical characteristics, but also their additional intrinsic properties that contribute to their use in this type of formulations. Safety issues regarding inorganic nanoparticles, based on toxicity studies, both to humans and the environment, as well as regulatory affairs associated with their use in dermopharmaceuticals and cosmetics, will be addressed.